Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 20 for “"activation processes"”.
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Activation processes in biology
Many processes in physics and biology can be understand through the framework of escape from a metastable state, including (but not limited to) the rates of chemical reactions, the unfolding of proteins, the nucleation of bubbles, and the condensation of gases. To understand the kinetics of these …
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Variation On A Theme: Comparing Strategies For Choosing Health Communication Campaign Message Topics
… among themes, nor the influence of spreading activation processes, in which exposure to messages about one theme may have effects that spill over to related, but non-targeted themes. This dissertation seeks to contribute to understanding of these issues in the context of anti-tobacco cigarette …
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Applications of Cobaloxime/Photoredox Co-operative Catalysis Toward Olefin Functionalization
… of decarboxylative transformations and olefin activation processes that allow access to reactive intermediates via light-driven catalysis. When carried out in the presence of cobaloxime catalysts, a cobalt complex designed to mimic vitamin B12, olefin reinstallation is achievable through …
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Epigenetic Memory of Mouse Intestinal Inflammation
… regions. Much remains to be understood about the activation processes of the repair mechanisms and to what extent the stem cells themselves can adapt to certain forms of damage, including molecular mechanisms related to gene regulation. Here, I show that in response to acute inflammation, …
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Understanding the activation-deactivation mechanism of glutamate receptor proteins at the single molecule level
… states of the ion channel. The gating action (activation and deactivation) of the ion channels are controlled by a number of molecules (ligands) interacting with specific binding sites. Hence, these binding sites can serve as potential drug targets for controlling the aberrant activation of the …
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Recombination lifetime analysis of deep levels in silicon
… of these recombination levels reflect the processes of energy exchange and provide information on the defect structure and energy spectrum and are thus of physical interest. Also since they control the excess carrier lifetime which is a critical parameter in many semiconductor devices they …
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Isolation of the Cytosolic C-Terminus Segment of Mammalian Kca Channel a Subunit
… and homeostatically fine tuning many biological activation processes in the cell. Great attention has been dedicated to the allosteric regulatory mecanisms by which the BK<sub>ca</sub> channel is activated or inhibited. Most of these mechanisms point to the involvment of cytoplasmic, C-terminal, …
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Synthesis and small molecule chemistry of the niobaziridine-hydride functional group
… species, Nb(N[Np]Ar)₃ (2a), via reversible C-H activation of the 3- ]H-containing N[Np]Ar ligand. At elevated temperatures, complex la-H rapidly converts to the neopentylimido complex, Nb(NNp)(Ar)(N[Np]Ar)₃ (3a), which is the product of N[Np]Ar ligand C'-N oxidative addition by putative …
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Evolution of protein structure function
… were identified to be the origin of different activation processes between CDK2 and its ancestor. The second biological question was to understand how does the wonder drug of century, Imatinib (Gleevec), exhibit high selectivity for a particular kinase involved in Chronic myelogenous leukemia. …
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Multi-Omics Analysis of 3D SKOV3 Ovarian Cancer Model Cell line Cultured on Novel Silicon-Titanium Diboride Micropatterned Substrate
… controlled proteolysis, complement iii activation processes were overlapping between day 7 and day 9 versus control. On day 9, there was molecular cues shift towards extracellular matrix remodeling, adhesion, angiogenesis, and PI3K-Akt-driven survival signaling, suggesting a more …
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Sistemi e dispositivi meccanici applicati a processi fisici e chimici
… cold-welding, fracturing and plastic deformation processes mediated by the generation, migration, and interaction of lattice defects. Depending on the nature of the powder and of its surroundings, the microstructural refinement can be accompanied by unusual physical and chemical transformations …
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Design of flow processes for C–H activation-type reactions
… bond forming reactions, the uptake of C–H activation in fine chemical manufacture is slow. Part of the reason for this deficiency is limited mechanistic understanding of these complex reactions. This can preclude industrial applications of either batch or continuous C–H activation …
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Electrical studies on new generations of oxide cathodes for CRT applications.
… of oxide cathodes depend largely on the activation process. In this thesis the electrical properties of these new types of oxide cathodes, supplied by LG Philips Displays, have been investigated in relation to the different activation processes. Scanning electron microscopic techniques …
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Regulation of BAX/BAK-Dependent Cell Death Program
… to activate Apaf-1. This initiates caspase activation, which results in irreversible cellular demise. The BCL-2 family proteins constitute a critical checkpoint in mitochondrion-dependent apoptosis. Multidomain proapoptotic BAX/BAK promotes mitochondrial outer membrane permeabilization, …
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Unconscious priming of "freely" chosen voluntary actions: Behavioral and electrophysiological evidence
… indicator of specific response activation processes. Under certain circumstanced this automatic response activation can bias free-choice actions although participants experienced the actions as freely chosen. In the test-phase of the first experiment more …
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Computational investigation of molecular recognition in plant hormone signal transduction
… hormones to their receptors and the subsequent activation of plant receptors. I have reported the free energy landscapes that quantitatively characterize the thermodynamics and kinetics of receptor-hormone binding and receptor activation processes. I have also identified the key intermediate …
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Development of palladium catalyzed intramolecular allylic C―H amination and oxidation towards pharmacological motifs
… group has been focused on the utility of C―H activation methodologies allowing for the streamlining of total synthesis. Using Pd(II)/sulfoxide catalysis, the White group has made significant developments in the area of allylic C―H oxidation and functionalization reactions. Using these …
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Coordination chemistry of unusual oxidation states of nickel and palladium relevant to homogeneous catalysis
… not limited to, cross-coupling catalysis, C-H activation, olefin polymerization, and cross-electrophile coupling. In addition, several metalloenzymes found in Nature that catalyze important small-molecule activation processes feature Ni at their active site. The commonly accepted mechanism of …
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Bio-inspired iron and cobalt complexes featuring a secondary coordination sphere: ligand design, complexation, and modeling of enzymatic processes
The activation of small molecules is crucial to the function of biological systems’ metabolic processes, detoxification, and cellular signaling. Metallocofactors and protein scaffolds often work in conjunction to attract and bind the small molecules, stabilize reactive intermediates, and shuttle …