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Showing 1 to 20 of 135 for “"Tissue-engineered"”.
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Electrospun Tissue Engineered Vascular Grafts
… in vivo pilot study showed patent grafts with tissue ingrowth and endothelium on the lumen for DP30 as well as the DP30+3%HepTBA group. The DP30 grafts show promise for the replacement of small diameter vessels. Heparin-eluting grafts will be further evaluated in long-term isolated loop models …
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Electrospun Tissue Engineered Vascular Grafts
… in vivo pilot study showed patent grafts with tissue ingrowth and endothelium on the lumen for DP30 as well as the DP30+3%HepTBA group. The DP30 grafts show promise for the replacement of small diameter vessels. Heparin-eluting grafts will be further evaluated in long-term isolated loop models …
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DRUG ELUTING TISSUE ENGINEERED VASCULAR GRAFTS
Electrospun Tissue Engineered Vascular Grafts (TEVG) have been synthesized with variable success. TEVG ≤5mm in diameter have had limited success due to poor patency outcomes with high rates of restenosis secondary to a phenomenon called Intimal Hyperplasia (IH). We have performed previous animal …
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Cryopreservation of tissue engineered skeletal muscle
Tissue engineered skeletal muscle plays an important role not only in the field of regenerative medicine, but also in emerging areas such as soft robotics, organ-on-a-chip models of disease, and drug testing. However, further expansion of the applications of tissue engineered skeletal muscle models …
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A tissue-engineered approach to hernia repair
Hernia repairs are among the most common surgical procedures performed, with more than 20 million hernias estimated to be repaired every year around the world. Mesh insertion is the most common method of treatment, with the mesh typically being made from polypropylene (PP). Significant …
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Design Of A Polysaccharide Derived Tissue Engineered Vascular Graft
<p>DESIGN OF A POLYSACCHARIDE DERIVED TISSUE ENGINEERED VASCULAR GRAFT</p> <p>By</p> <p>Irina Robu</p> <p>November 2010</p> <p>Advisor: Dr. Howard Matthew</p> <p>Major: Chemical Engineering</p> <p>Degree: Doctor of Philosophy</p> <p>As the most frequent congenital anomaly and the leading cause of …
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A Tissue-Engineered Blood Vessel Model for Vascular Aging
… in isolation in vivo. The Truskey lab developed tissue-engineered blood vessels (TEBVs) which recapitulate the structure and function of an arteriole in vitro. These vessels can be fabricated rapidly, perfused immediately after fabrication, and reach functional maturity after a week. Measurements …
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Biodegradable polymer scaffold fabrication and the creation of tissue-engineered bone
… environment, would be sufficient to create tissue engineered bone. A method was developed to fabric ate three-dimensional poly(DL-lactic-co-glycolic acid) (PLGA) foams which involves the production of PLGA/gelatin composites followed by leaching of the embedded gelatin microspheres. These …
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Development of a Tubular Biological Tissue-Engineered Heart Valve with Growth Potential
This thesis investigates tissue-engineered cardiovascular devices for pediatric patients and their function and growth potential in preclinical testing. Specifically, engineered tissue tubes were fabricated by entrapping dermal fibroblasts in a fibrin gel and allowing them to replace it with …
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Development and Characterization of Tissue Engineered Blood Vessel Mimics Under "Diabetic" Conditions
<p>The development of tissue engineered blood vessel mimics for the testing of intravascular devices in vitro has been established in the Cal Poly tissue engineering lab. Due to the prevalence of cardiovascular disease in diabetic patients and minimal accessible studies regarding the interactions …
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Biohybrid swimmers at low Reynolds number powered by tissue-engineered neuromuscular units
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2022-04-06 without embargo terms
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Biomechanical and biochemical properties of tissue engineered neocartilage before and after implantation
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2003.
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A Tissue-Engineered Microvascular System to Evaluate Vascular Progenitor Cells for Angiogenic Therapies
<p>The ability of tissue engineered constructs to replace diseased or damaged organs is limited without the incorporation of a functional vascular system. To design microvasculature that recapitulates the vascular niche functions for each tissue in the body, we investigated the following …
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Tissue-engineered in vitro models for studying lymphatic morphogenesis, pathogenesis, and drug delivery
The lymphatic system is a network consisting of lymphatic vessels and lymphoid organs such as lymph nodes (LNs), which drain excess interstitial fluid and eventually return it to the blood circulatory system via the thoracic duct and subclavian veins. It plays a key role in interstitial fluid …
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Tissue-engineered liver microreactor as an in vitro surrogate assay for gene delivery
… environment and responses of in vivo liver tissue. This thesis aimed at developing an alternative in vitro gene delivery assay based on the Tissue-Engineered Liver Microreactor, a culture system designed to facilitate the morphogenesis of three-dimensional tissue-like structures from …
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Tissue Engineered Scaffolds and Three Dimensional Tumor Constructs to Evaluate Pulsed Electric Field Treatments
… use of irreversible electroporation (IRE) for tissue engineering applications and as a cancer ablation therapy. IRE uses short, high-intensity electric pulses to create pores in a cell's membrane and disrupt its stability. At a certain energy level, damage to the cell becomes too great and it …
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