Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Targeting Drug Delivery"”.
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Development of polymeric drug delivery vehicles for targeted cancer therapy
… to generalize a method for targeted anti-cancer drug delivery. Hydrophilic polymer-drug conjugates involve complicated synthesis; drug-encapsulated polymeric nanoparticles limit the loading capability of payloads. This thesis introduces the concept of nanoconjugates to overcome difficulties in …
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INVESTIGATION OF LIGAND SIZE ON TARGETED PLGA NANOPARTICLES FOR HER2 BREAST CANCER: TRASTUZUMAB AND ITS ScFv ANTI-HER2 ANTIBODY
… the effect of various formulation parameters on targeting human epidermal growth factor receptor-2 (HER2) specifically in breast cancer. Poly (D, L-lactide-co-glycolide) (PLGA) polymer, which is approved by FDA, was used to form nanoparticles (NPs) encapsulating docetaxel (DOC) as chemotherapy. …
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Entwicklung von tumorhemmenden Polymer-Wirkstoff-Konjugaten des Zytostatikums Methotrexat auf der Basis von linearem Polyethylenglykol
Ziel dieser Arbeit war es, verschiedene Polymer-Wirkstoff-Konjugate bestehend aus dem Zytostatikum Methotrexat (MTX) und linearem Polyethylenglykol (PEG) zu synthetiseren und auf ihre tumorhemmenden Eigenschaften hin zu untersuchen. Aus diesen Ergebnissen sollten Struktur-Wirkungs-Beziehungen für …
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Selective in vivo metabolic labeling for cell targeting and immune regulation
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-08-01
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Bioengineering functional polymer systems for glycan-based targeting and drug release
Bioengineering drug delivery facilitates re-potentiation of existing drugs and drug candidates, bypassing hurdles in novel drug development and accelerating the advance of medicine. Drug delivery strategies aim to enhance therapeutic effect by enhancing delivery to the target cells or tissues, …