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Showing 1 to 20 of 114 for “"TPR"”.
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Strengths and Weaknesses of Hybrid TPR Technology for Obtaining Structural and Mechanistic Insights into TPR Proteins
<p>Tetratricopeptide (TPR) repeats are a 34-residue helix-turn-helix motif that when repeated pack into a superhelical structure. TPR domains are frequently found mediating protein-protein interactions, often through a central groove. One protein complex bearing numerous TPR repeats is the Anaphase …
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The Myosin-Binding UCS Domain but not the Hsp90-Binding TPR Domain of the UNC-45 Chaperone is Essential for Myosin Accumulation and Assembly in Caenorhabditis elegans
… A band assembly. Removal of the Hsp90-binding TPR domain of UNC-45 does not affect rescue. Similar results were obtained with overexpression of the same fragments in wild-type nematodes when assayed by diminution of myosin accumulation and assembly. Titration experiments show that on a per …
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Investigating household energy poverty in South Africa by using unidimensional and multidimensional measures
… share, also known as Tenth-Percentile Rule (TPR) (unidimensional) and the multidimensional energy poverty index (MEPI) using data from wave 1 (2008) and wave 4 (2014-2015) of the National Income Dynamic Study (NIDS) of South Africa. A 10 percent threshold was used for the energy-budget share …
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Understanding tetratricopeptide repeats of <i>O</i>-GlcNAc transferase
… contains an N-terminal tetratricopeptide repeat (TPR) domain, with some evidence to suggest that this domain plays a role in substrate and adaptor protein binding. However, our understanding of the mechanisms underlying OGT substrate recognition and specificity remains limited. The work described …
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Structural Insights into the Mechanisms Controlling the Modification and the Readout of Histone H3.1
… we characterized the tetratricopeptide repeat (TPR) domain of TONSOKU (TSK), a DNA damage response protein, as a variant-specific reader for histone H3.1 and established a role for H3.1 in replication-coupled DNA repair via the homologous recombination pathway. Using X-ray crystallography, I …
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Recovering from Distributable Thread Failures with Assured Timeliness in Real-Time Distributed Systems
… three distributable thread integrity protocols (TPR, D-TPR and W-TPR) are presented. We show that AUA combined with any of the protocols presented bounds the orphan cleanup and recovery time, thereby bounding thread starvation durations and maximizing the total thread accrued timeliness utility. …
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EXAMINING THE ROLE OF THE XAB2 PROTEIN IN HOMOLOGOUS RECOMBINATION
… protein contains 15 tetratricopeptide repeat (TPR) motifs, which likely enable protein-protein interactions. While XAB2 is speculated to have a role in transcription coupled repair and pre-mRNA splicing, its role in HR pathway is uncertain. The overall hypothesis for my thesis is that XAB2 …
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Estimation of cardiovascular indices by analysis of the arterial blood pressure signal
… output (CO), and total peripheral resistance (TPR) by analysis of the arterial blood pressure (ABP) signal. The algorithms incorporate cardiovascular physiology within the framework of a generalized Windkessel model, which is a widely accepted cardiovascular model. Algorithms to identify end …
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Cardiovascular responses to sustained isometric force production of the finger flexor and knee extensor muscle groups in weight-trained and untrained young men
… $\times$ SV), and total peripheral resistance (TPR = MAP/CO) were derived for each recording period. Multivariate analysis of variance (MANOVA) was used to statistically analyze the significance (p $\le$.05) of the mean differences between subject groups (weight-trained and untrained) and muscle …
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Moderating effect of a single aerobic exercise session on the cardiovascular response to a stressful procedure 45 minutes later
… volume (SV) and total peripheral resistance (TPR) were measured at baseline, during a pre-stressor anticipation period, and during the cold pressor test. stroke volume was measured with impedance cardiography and total peripheral resistance (TPR) was estimated. SBP was significantly lower …
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Die Funktion des spaghetti-Gens in Drosophila melanogaster
… ein 534 Aminosäuren langes Protein, welches eine TPR-Domäne, bestehend aus drei TPR-Motiven, aufweist. Homozygot spaghetti-mutierte (spag-) Tiere sind nicht in der Lage, sich zu verpuppen. Sie sterben als überalte Larven des dritten Stadiums. Diese Larven zeigen melanotische Pseudotumore, ihre …
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Hidrogenação de catalítica de acetileno sobre catalisadores de paládio e catalisadores bimetálicos de paládio e prata
… foi analisada por quimissorção de CO, TPR de H2 e medidas de área superficial pelo método BET. Os catalisadores de paládio e paládio/prata mostraram-se bastante ativos e seletivos para a reação de hidrogenação de acetileno. Os resultados dos ensaios de quimissorção de CO indicaram que …
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Investigating Mechanisms of Nuclear mRNA Export
… half of this thesis, I characterize the role of TPR, a nuclear pore basket protein, in mediating nuclear retention and export of mRNAs. While splicing has been shown to enhance nuclear mRNA export, it remains unclear whether RNAs generated from intronless genes use specific machinery for their …
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The relationship between markers of disease severity in obstructive sleep apnea patients and hemodynamic and respiratory function during graded exercise testing
… of exercise Qc and total peripheral resistance (TPR), these responses could then be investigated acutely in the context of evaluating the relation of these measures to markers of disease in OSA patients. (2): The primary research aim was to describe the extent to which graded exercise testing may …
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Creating a Curriculum for Preschool Educators in Asia: How to Teach Kindergarteners Speaking and Listening Skills in English through Games
… as teaching methods. Total Physical Response (TPR) and Communicative Language Teaching (CLT) are used as the theoretical frameworks for this project.</p> <p><em>Key words</em>: English education, early childhood education, Asia, TPR, CLT</p>
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Signal processing approaches to analyzing patient cardiovascular state
… output (CO), total peripheral resistance (TPR), and PPV of patients who experience adverse outcomes to those who do not could help explain the link between adverse outcomes and intraoperative blood pressure variations. Data from patients undergoing cardiothoracic surgery was used to …
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Architecture and CAD for Nanoscale and Three-Dimensional FPGA
… considered. Using the 3D physical design tool TPR as a base, a new 3D routing algorithm is developed, which improves the average performance of two-layer designs by over 22% and three-layer designs by over 27%.
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Crosstalk of TTC5 cofactor and the estrogen receptor in breast cancer
… is a 440 amino acid protein,predicted to have 6 TPR (tetratricopeptide repeat) motifs and 4 LXXLL motifs, which areknown to mediate protein-protein interactions. TTC5 has been shown previously tointeract with and regulate the glucocorticoid receptor, which belongs to the same familyof nuclear …
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Investigation of NH3 and no adsorption over Cu/SAPO-34 and Cu/AlOo3 catalysts for NH3–SCR system
… chemisorption, temperature-programmed reduction (TPR), and temperature-programmed desorption (TPD) with three different conditions (NH_3, NO, combined NH_3-NO) to evaluate the adsorption of ammonia and nitric oxide. Cu/SAPO-34 catalyst has shown higher ammonia adsorption capacity compared to …
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Ozone Decomposition and Acetone Oxidation on Manganese Oxide Catalysts
… area analysis, temperature-programmed reduction (TPR), and oxygen chemisorption. The use of these techniques allowed better understanding of the nature of the catalysts. Activity tests were carried out in the acetone oxidation reaction and it was found that the usage of ozone substantially reduced …
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