Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Systemic Immunity"”.
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Effects of prebiotic fibre diets on rat mucosal intestinal and systemic immunity and in vitro mechanistic analysis of anti-inflammatory effects of lactobacillus strains on rat and human intestinal epithelial cells
… fibres on the immune system at the mucosal and systemic level, using Biobreeding rats. L. rhamnosus demonstrated the ability to decrease proinflammatory cytokine and Toll-like receptor agonist-induced IL-8 and CINC-1 production from human and rat IEC, respectively. The timing of L. rhamnosus …
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Effect of Systemic Versus Localized Bacillus Calmette-Guérin Immunotherapy on Bladder Cancer Progression: Novel Role for Trained Immunity
… is mounting evidence that the activation of a systemic immune response is critical for the induction of local anti-tumour responses. Based on this knowledge, we hypothesized that compared with the standard intravesical route, systemic intravenous administration of BCG will result in improved …
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T2 Mycotoxicosis in Swine Following Topical Application, Intravascular Administration and Inhalation Exposure
… signs, pathologic changes and pulmonary and systemic immunity of T-2 toxicosis in swine following a single, topical (15 mg/kg), intravascular (0.6 to 5.4 mg/kg) or inhalation (8 or 9 mg/kg; 20 to 30 percent retention) exposure.
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DESIGNING ANTI-PDL1 ANTIBODY CONJUGATED POLYMERIC COACERVATES AS A NOVEL “NANO-IMMUNOTHERAPY” AGAINST HEPATOCELLULAR CARCINOMA
… rise. While progress has been made in enhancing systemic therapies for HCC, resistance development and toxicity of these treatments are common. To circumvent these issues, a novel “nano-immunotherapy” to deliver encapsulated cationic polycarbonates for induction of immunogenic cell death and …
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Expanding Antigen-specific Tr1 Cells to Treat Autoimmunity
… against self antigens, without impairing systemic immunity. Our lab has been developing a nanoparticle-based therapy which consists of disease-relevant peptide-MHC complexes coated on iron-oxide nanoparticles (NPs). We have demonstrated that the therapeutic effects exerted by these NPs are …
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HEPATOCYTES COORDINATE A SYSTEMIC ENDOCRINE NETWORK IN CANCER
… of solid tumors lack productive tumor T cell immunity, and the mechanisms that coordinate T cell exclusion remain incompletely understood. Accumulating evidence suggests that while cancer cell intrinsic and tumor microenvironmental cues contribute to immune suppression, tumor extrinsic …
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Modulation of Immune Responses Induced by Vaccination Against Bovine Respiratory Syncytial Virus
… would result in the induction of protective immunity against RSV without risk of deleterious effects. We observed in calves that parenterally delivered FI-bovine RSV (BRSV) formulated with CpG ODN resulted in a shift towards a Th1-biased or more balanced immune response that was protective …
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Relative level of glucocorticoid and progesterone receptor: implications for immune and reproductive functions in women
… that GR and PR expression levels are relevant to immunity against pathogens in the female genital tract (FGT) and systemic immunity. PR protein expression is well characterised ex vivo in FGT tissues while very little is known about GR protein expression ex vivo in the FGT. Immune cells patrol the …
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Effect of HIV infection and pregnancy on parameters of vaginal immunity
… the cervicovaginal immune environment. Like with systemic immunity, innate and adaptive immune mediators are integrated in the efficiency for fighting infections in the female genital tract. Our study addresses the role of pregnancy and HIV infection on concentrations of cytokines in genital tract …
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Contagious ecthyma virus infection of sheep: virologic and immunologic investigations
… not be used to predict the degree of protective immunity. Measurement of the neutralizing antibody and virus-specific lymphocyte transformation responses suggested that there was a minimal systemic immune response following CE virus inoculation. Higher levels of systemic immunity may be induced …
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Impact of early nutrition on the development of lung immunity in the piglet
… on the impact it has on the development of lung immunity in the piglet. In the first section, an introduction is given. In short, neonates are susceptible to infection early in life, especially respiratory infections (Murphy et al. 2008). Respiratory infections are a major cause of morbidity and …