Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 49 for “"Stacking Interactions"”.
-
Intramolecular Stacking Interactions Determined by Fluorescence Quenching
Made available in DSpace on 2014-12-13T20:09:52Z (GMT). No. of bitstreams: 1 7624093.pdf: 4061431 bytes, checksum: d0f51b1ad5ca0aecde8c3446dfc14c3a (MD5) Previous issue date: 1976
-
Intramolecular Stacking Interactions. A Study in Three Parts
Made available in DSpace on 2014-12-13T20:10:01Z (GMT). No. of bitstreams: 1 7709131.pdf: 3684789 bytes, checksum: 94f567e248ea54af108c070dc92fed85 (MD5) Previous issue date: 1976
-
Towards a fragment approach to haemozoin inhibiting antimalarials : exploration of coordination and π-stacking interactions with Fe(III)PPIX by spectroscopy and synthesis
Investigation of coordination and π-stacking interactions with ferriprotoporphyrin IX (Fe(III)PPIX) using a fragment approach was undertaken in order to propose and synthesise novel compounds which followed a hypothesised mechanism of action to inhibit β-haematin formation. Coordination of a series …
-
The Role of CH–π Interactions in Protein-Carbohydrate Binding
… is driven by several types of non-covalent interactions: hydrogen bonding, metal ion coordination, and the less well-understood CH–π interactions. CH–π interactions are pervasive in protein-carbohydrate binding sites and have emerged as critical drivers of protein–carbohydrate recognition; …
-
The stereoselective synthesis of a novel aromatic peptide nucleic acid (APNA) oligomer
… 70 were observed which suggested that base stacking interactions in the oligomers may be favorable.
-
Part I. Molecular Tweezers: Synthetic Receptors for Nucleotide Bases. Part II. Molecular Self-Assembly: Design of a Helical Aggregate
… The cooperativity of hydrogen bonding and $\pi$-stacking interactions resulted in the efficient complexation of 9-propyladenine by 28, a association constant of 25,000 M$\sp{-1}$ was measured. The nucleoside selectivity of 28 was also studied. Studies suggested that the unique microenvironment …
-
Molecular tweezers: Synthetic receptors for the DNA base adenine
… a combination of hydrogen bonding and $\pi$-stacking interactions. They were synthesized in a convergent fashion that was fast and efficient. A new methodology for 9-substituted acridines was developed to facilitate the syntheses of molecular tweezers containing acridine chromophores. A novel …
-
Computational modeling of melanin aggregation
… that DHI-eumelanin aggregates through nanoscale stacking, and that water molecules are present as a shell around the aggregates. The aggre- gation process is affected by the concentration of the protomolecules in aqueous solutions. The physical mechanisms of stacking were investigated using …
-
"fine-tuning" of ribosomal structure and functions by pseudouridylation and rna-protein interactions
… functions by pseudouridylation and RNA-protein interactions</p> <p>by</p> <p>JUN JIANG</p> <p>AUGUST 2012</p> <p>Advisor: Prof. John SantaLucia Jr.</p> <p>Major: Chemistry (Biochemistry)</p> <p>Degree: Doctor of Philosophy</p> <p>Ribosomal structure and functions appear to be "fine-tuned" by …
-
Design and Synthesis of Molecularly Encapsulated Conjugated Materials for Organic Electronics.
… to their intermolecular and intramolecular interactions. In conjugated polymers, charges or excitons can transport either along the conjugated backbone or intermolecularly via π-stacking interactions. Yet, our understanding of what each type of interaction contributes, is still rather …
-
Computational and Pharmacological Characterization of HDAC6 Inhibition and Function
… the monomer and dimer forms. Inhibitor – residue interactions are also monitored and important residues, in particular H139, H140, H610 and H611 for inhibitor binding are uncovered in both domains. In addition, π-π aromatic stacking interactions are also observed between W208 (CD1) or F680 (CD2) …
-
On the Nature of Weak Intermolecular Forces: a First Principles Approach to Hydrogen Bonding and Pi-Type Interactions
… used to computationally study these type interactions are considered. Chapter 4 discusses the effects of ?-stacking interactions between aromatic amino acid side chains and adenine bearing ligands in crystalline protein structures. The 26 toluene/(N9-methyl-)adenine model configurations …
-
Role of aromatic pi-stacking on the aggregation of human islet amyloid polypeptide (hIAPP)
… Aggregation is thought to be mediated by pistacking interactions between phenylalanine residues of hIAPP. In this study, the hIAPP 1-19 sequence was modified by replacing phenylalanine with alanine and naphthylalanine, to study if the modification of the aromatic side chain alters …
-
Structural studies of coordination networks based on multitopic organic ligands and silver(I) salts
… either aromatic $\pi$-$\pi$ or silver-aromatic interactions. A correlation between the degree of interpenetration and the cavity sizes that are generated in a single net using the geometrical requirements of the $\pi$-stacking interactions has also been obtained.
-
The principles of molecular gel formation
… molecules experiencing hydrogen bonding and π-π stacking interactions, making them distinct from typical gels formed by aggregation of colloidal particles or crosslinking of polymer chains. The remarkable structural and mechanical properties of these materials offer a wide range of potential …
-
Non-Covalent Interactions in Water Using Synthetic and Biological Receptors
… the factors that govern the nature of aromatic interactions in water. The rational design and interpretation of the supramolecular behaviour of aromatic interactions in aqueous solution represents a major challenge. First, aromatic interaction energies are strongly affected by the geometry of …
-
Molecular-scale devices from first principles
… are attracted to each other through p-stacking interactions driven by redox reactions. We show that counterions strengthen this interaction further through enhanced screening of the electrostatic repulsion. Many molecular scale devices require contact with a metallic conductor, we also …
-
Synthesis of new substituted organosulfur donors for the preparation of conductive and multifunctional materials
… in the solid state by involving non-covalent interactions such as hydrogen bonding and/or additional π-π stacking interactions as in donors (IV) and (V). [Figure 3. Examples of enantiopure donors prepared in chapter 3.]. In chapter 4 the investigation of the coordination chemistry of novel …
-
Crystallographic and Modeling Studies Suggest that the SKICH Domains from Different Protein Families Share a Common Ig-like Fold but harbor substantial Structural Variations
… Extensive pairwise and clustered aromatic π-stacking interactions are present in the TAX1BP1 SKICH domain. The aromatic residues mediating these interactions can be classified into four groups with varying degrees of conservation among different protein families. The interactions mediated by …
-
Unusual Electron Transfer Rate Effects due to Pyridyl Ring Substituents and Trace Group VIII b Hexacyano Complexes as Added Salts
… or it could be that energetically-favorable p-p stacking interactions (known to be common in compounds bearing the phenyl rings) may be helping to enhance bimolecular precursor complex formation.</p> <p>Salt effect studies showed that the apparent catalytic activity of the salts muconate, …
Page 1 of 3