Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Solid organ transplantation"”.
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Nurses' perceptions of clinical competency and individualized care in relation to solid organ transplantation
… (TNC) and individualized care (IC) levels for solid organ transplant (SOT) recipients, living donors, and their families while also exploring the relationships among nurse characteristics, TNC, and IC. Three hundred ninety-one participants, comprising U.S. nurses caring for SOT recipients, …
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Characterisation of Alloantibody-Human Leukocyte Antigen Interactions to Improve Immunological Risk Assessment in Solid Organ Transplantation
… mediated rejection remains a major challenge in solid organ transplantation, where the development of immunoassays for characterisation a recipient’s donor HLA-specific antibodies has revolutionised the field of solid organ transplantation. These immunoassays are essential for patient evaluation, …
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The role of ischaemia-reperfusion injury and mitochondrial dysfunction in organ transplantation
… injury and mitochondrial dysfunction in organ transplantation Ischaemia and subsequent reperfusion is inherent to solid organ transplantation and contributes to tissue damage, organ dysfunction, and worse recipient outcome. Demand for organs for transplantation in the UK has led to the …
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Gene Therapy and Stem Cell Therapy to Improve the Outcome of Human Islet Transplantation
… in 1990s, the Edmonton Protocol for human islet transplantation has helped more than 500 patients with type 1 diabetes worldwide and met great success from bench to bedside. The Edmonton Protocol involves isolating islets from a cadaveric donor pancreas by enzymatic digestion and infusing into …
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Study of Physiologic and Immunologic Incompatibilities of Pig to Human Transplantation
Solid organ transplantation is limited by available donor allografts. Pig to human transplantation, xenotransplantation, could potentially solve this problem if physiologic and immunologic incompatibilities are overcome. Genetic modifications of pigs have proven valuable in the study of …
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CD4 T cell allorecognition pathways in acute and chronic allograft rejection
Solid organ transplantation is now an established and effective treatment option for end-stage organ failure. Whilst early outcomes have improved significantly over recent decades, longer-term outcomes have changed little. Despite advances in immunosuppression, most transplanted organs suffer an …
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Investigation of novel therapeutic strategies in B cell and antibody mediated disease
… be pathogenic in some autoimmune diseases and in solid organ transplantation. In addition to antibody generation, there is increasing interest in the antibody-independent functions of B cells, including their ability to regulate immune responses via the production of IL10. In this thesis I firstly …
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Klinische Studie zum Mundhygieneverhalten und zur zahnärztlichen Aufklärung von Patienten vor und nach Organtransplantation
… die orale Gesundheit bei Patienten vor und nach Organtransplantation zu gewinnen und den Kenntnisstand der Patienten über die Korrelation von Mundgesundheit und Transplantation zu eruieren. Die Untersuchung gliederte sich in zwei Teile. An die allgemeine und zahnärztliche Anamnese zur …