Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 28 for “"Signal Recognition"”.
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A satellite signal recognition system
… a wide variety of services. They carry wideband signals, such as television, and narrowband signals, such as business data networks. This paper describes a signal recognition system for the narrowband signals found on Ku-band satellites. Using readily available equipment, it saves observed …
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Stress-signal recognition in the unfolded protein response
… receptors, extracellular matrix components, and signalling molecules (Kelly, 1985). Malfunctions in this pathway are linked to diseases like cancer, diabetes, and neurodegeneration (Sherwood, L., 2015; Uhlen *et al*, 2015; Pohlschroder *et al*, 2005; Wang & Kaufman, 2016). Whilst effector …
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Biochemical and genetic analysis of a fission yeast ribonucleoprotein homologous to signal recognition particle
… on a ribonucleoprotein complex known as signal recognition particle (SRP). SRP is composed of six polypeptides and one molecule of 7SL RNA. A homolog of mammalian SRP RNA was found in the fission yeast, Schizosaccharomyces pombe. The gene encoding the S. pombe RNA was cloned by screening …
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Analysis of essential structural and functional elements in the GTP-regulated signal recognition particle cycle
I have investigated signal recognition particle (SRP)-mediated protein targeting using a combination of genetic, biochemical, and molecular sequence analysis techniques. First, I consider the SRP cycle from the perspective of molecular evolution. This analysis provides insight into the significance …
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Nuclear Export Signal Recognition by CRM1 Carrying the Oncogenic E571K Mutation and Structure-Based NES Prediction
… interactions with 22 different nuclear export signals (NESs) from protein cargos using a low-throughput differential photobleaching assay. However, hundreds of very diverse CRM1 cargos and their NESs have yet to be characterized, limiting our understanding of the biological roles of CRM1 in …
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The Importance of RNA Sequence and Structure in the Assembly and Function of Signal Recognition Particle
Signal recognition particle (SRP), the ribonucleoprotein responsible for the recognition and targeting of nascent secretory proteins to the endoplasmic reticulum, is composed of 7SL RNA, along with six polypeptides. Earlier work in our lab identified a homolog of 7SL RNA in S. pombe, showed by gene …
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Genetic analysis of Schizosaccharomyces pombe 7SL RNA
Signal recognition particle (SRP), a ribonucleoprotein composed of six polypeptides and one molecule of 7SL RNA, is required for translocation of secretory proteins into mammalian microsomal vesicles in vitro. In order to investigate the function of the RNA component of SRP, mutations were …
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Molecular and Biochemical Analysis of the Histidine Kinase CusS and its Role in Metal Resistance in Escherichia coli
… the periplasmic space of E. coli. Extracellular signals are transduced into the cell through phosphotransfer reactions between the prototypical histidine kinase CusS and the response regulator CusR. Copper sensing by the periplasmic domain of CusS is proposed to initiate signal transduction in …
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Unterschiedliche Funktionen von SRP und SecA beim Transport eines bakteriellen Proteins
… während ihrer Synthese am Ribosom anhand ihrer Signal-Anker-Sequenzen vom Signal recognition particle (SRP) erkannt; ihre Zielsteuerung und Integration in die Innenmembran erfolgen kotranslational und werden von SRP und seinem Rezeptor FtsY vermittelt. Sekretorische Proteine (lösliche …
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Vibrotactile pattern recognition on the torso : effects of concurrent activities
… how concurrent activity affects vibrotactile signal recognition. An overall accuracy recognition rate of 90% or greater was desired from each of the signals in the each of the tasks. The first experiment asked subjects to wear the tactile display and walk while responding to signals. The …
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RNA Localization and Translational Regulation on the Endoplasmic Reticulum
… cell fate specification, and synapse formation. Signal sequence-encoding mRNAs are localized to the endoplasmic reticulum (ER) membrane by either of two mechanisms, a canonical mechanism of translation on ER-bound ribosomes (signal recognition particle pathway), or a poorly understood direct ER …
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Neuromorphic audio processing through real-time embedded spiking neural networks.
In this work novel speech recognition and audio processing systems based on a spiking artificial cochlea and neural networks are proposed and implemented. First, the biological behavior of the animal’s auditory system is analyzed and studied, along with the classical mechanisms of audio signal …
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Hand (Motor) Movement Imagery Classification of EEG Using Takagi-Sugeno-Kang Fuzzy-Inference Neural Network
… methods fail to offer adaptability and proper signal recognition for output devices. Human anatomical differences prevent the use of a fixed model system from providing consistent classification performance among various subjects. Furthermore, notoriously noisy signals such as …
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Terrain sensing and estimation for dynamic outdoor mobile robots
… presented. The second, model-free method takes a signal recognition-based approach to analyze inertial measurements to detect robot immobilization. Both approaches are experimentally validated on a robotic platform traveling on a variety of outdoor terrains. Two detector fusion techniques are …
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Parallel effects of signal peptide hydrophobic core modifications on cotranslational translocation and posttranslational cleavage by purified signal peptidase
… amino terminal extension sequence known as the signal peptide. Signal peptides contain a central core of uncharged amino acids that are usually hydrophobic in nature. The hydrophobic core of the parathyroid hormone (PTH) signal peptide is composed of 12 contiguous hydrophobic amino acids. …
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Robust speaker recognition in presence of non-trivial environmental noise (toward greater biometric security)
The aim of this thesis is to investigate speaker recognition in the presence of environmental noise, and to develop a robust speaker recognition method. Recently, Speaker Recognition has been the object of considerable research due to its wide use in various areas. Despite major developments in …
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In vitro Untersuchungen zum Translationsarrest in Escherichia coli
… in der Säugetierzelle wahrnimmt, ist der Signal Recognition Particle (SRP). Dieser bindet an die Signalsequenz gerade entstehender Proteine, unterbricht deren Translation und steuert das Ribosom mit der naszierenden Proteinkette zur Membran des Endoplasmatischen Retikulums (ER). Die …
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Pattern Recognition in Signals Through Rough Concept Bounding
The recognition of complex signal patterns is generally considered to be a difficult task. Analytical approaches and rule-based expert systems have been used for the recognition of signals or waveforms. Using an analytical approach requires mathematical training and substantial knowledge of the …
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In vitro-Untersuchungen zum Sekretionsmechanismus der beta-Lactamase in Escherichia coli
… in Abhängigkeit von SecA. <br>2. Das bakterielle signal recognition particle (SRP) und sein Rezeptor FtsY vermitteln die kotranslationale Zielsteuerung und Integration polytoper Innenmembranproteine an bzw. in das SecYEG-Translokon. <br>Nicht alle Innenmembranproteine sind jedoch ausschließlich …
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Structural Characterisation of the Mammalian SRP Receptor
… This requires the specific interaction of the signal recognition particle (SRP), a ribonucleoprotein, with its receptor (SR). The eukaryotic SR is a heterodimeric protein consisting of SRα and SRβ which is anchored to the ER membrane. In all three kingdoms of life the conserved GTPases in SRP …
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