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Showing 1 to 2 of 2 for “"Sec17"”.
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Biophysical Characterization of SNARE Complex Disassembly Catalyzed by NSF and alphaSNAP
… fuer die Isoform betaSNAP und das Hefe-Homolog Sec17 konserviert ist. Ausserdem habe ich mithilfe verschiedener Mutanten und Inhibitoren moegliche regulatorische Angriffspunkte charakterisiert. Ein Antikoerper gegen die N-terminal Domaene von NSF, der auch im Rahmen dieser Arbeit hergestellt …
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The regulation of yeast homotypic vacuole fusion by phosphatidic acid and diacylglycerol
… by their co-chaperones Sec18 (mammalian NSF) and Sec17 (mammalian α-SNAP) in an ATP dependent priming stage. Tethering first brings two fusing compartments into contact with each other via interactions between the Rab GTPase Ypt7 and its effector HOPS complex. Once tethered, compartments are …