Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 231 for “"SERS"”.
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Ultratrace Neurotransmitters SERS Sensing
Surface-enhanced Raman scattering (SERS) spectroscopy is a powerful analytical technique for ultrasensitive detection of chemicals and biomolecules. As the high sensitivity of SERS requires analytes to be in close contact with a plasmonic substrate, the detection of analyte molecules with low …
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Tailoring plasmonic substrates for SERS
SERS is a useful spectroscopic technique that was discovered 30 years ago, and has recently seen a renaissance in research. Sphere segment void (SSV) substrates have been developed as reproducible, stable SERS substrates by electrodeposition of a metal through a colloidal template.<br/>The effect …
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Mėginių apdorojimo poveikis bioaudinių SERS spektroskopijai /
… Surface-enhanced Raman scattering spectroscopy (SERS) of biotissue analysis. SERS is a very powerful tool to detect and help characterize biomolecules with high sensitivity and selectivity. However, this analysis method is easily influenced by various factors such as sample preparation, tissue …
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Raman and SERS studies of filamentous fungi
… and decay. Surface-enhanced Raman scattering (SERS) has attracted significant attention as an analytical method for chemical and biological identification. For SERS experiments, it is essential to generate gold nanoparticles (AuNPs) with proper sizes and shapes. Raman and SERS imaging of fungi …
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SERS-based nanoparticle biodetection using carbohydrate-lectin interactions
… of surface enhanced Raman scattering (SERS) signals. Aggregation of the glyconanoparticles in the presence of a variety of carbohydrate-binding proteins (lectins) was measured via changes in the extinction profile, size and the SERS response of those particles. Nanoparticle aggregation …
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Substratos vítreos com nanoestruturas metálicas para aplicações SERS
… Raman Intensificada por Superfície (SERS). Os metais usados, geralmente, são prata, ouro, cobre e níquel uma vez que a SPR desses metais estão localizados na região do visível. Neste trabalho, foi sintetizado e caracterizado um material híbrido, consti- tuído de nanopartículas de …
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Surface wetting methods compatible with solid SERS substrates
… used for surface-enhanced Raman spectroscopy (SERS). Effectiveness of the sensors depends on how well ligand and analyte molecules can diffuse into the regions of highest enhancement. In liquid phase sensing, this is often contingent upon the ability of the solvent to completely wet the …
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Portable EIS and SERS sensing with flexible sensors
… wafer scale, flexible, polymer-based nano-pillar SERS sensor with an enhancement factor (EF) as high as 4.81 × 108 for the silver-based sensor. This high EF resulted from better adhesion between the substrate and detecting target, as well as the extended hotspots from the dense silver …
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On the nature of SERS from plasmonic nanostructures
The nature of surface-enhanced Raman scattering (SERS) on nanostructured surfaces is explored using both inorganic and organic-based systems and a variety of environmental perturbation mechanisms. Experimental optical characterisation systems are developed and existing systems extended to …
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SERS & efficacy assessment of anti-cancer drug-nanoparticle conjugates
… of a NP (surface enhanced Raman spectroscopy (SERS)). Two metals were compared for signal detection, namely gold and silver NPs. Once EL conjugate imaging was achieved, the anti-proliferative efficacy and cytotoxicity of the NP conjugated erlotinib to the free drug was assessed. EL-NP …
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DNA diagnostic assays using Surface Enhanced Raman Scattering (SERS)
… strong surface enhanced Raman scattering (SERS) responses through specific hybridisation events which correlate to the presence of targeted sequences. During this study, the attraction of oligonucleotides onto metal nanoparticles was shown to be driven through the DNA nucleobases. …
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Characterisation of bacteria by surface enhanced Raman spectroscopy (SERS)
… techniques. Surface-enhanced Raman spectroscopy (SERS) has received considerable attention as a potential method for the characterisation of bacteria.<br/><br/>The aims of this thesis were to (i) develop a SERS method that would characterise and distinguish between different bacterial species, …
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Gold Nanoshells: Synthesis and Applications to In Situ SERS
In situ surface-enhanced Raman spectroscopy (SERS) is a powerful technique for probing molecular adsorption and reaction at the solid-liquid interface due to its very high surface sensitivity, wide applicable frequency range, and relative insensitivity to water. However, a low SERS activity and …
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Detection of food contaminants by SERS and nanopore technology
… a novel surface-enhanced Raman spectroscopy (SERS) method was developed coupled with simplified extraction method and a novel gold nanorod substrate to detect banned aquaculture biocides (malachite green (MG) and crystal violet (CV)) and their mixture (1:1) in aqueous solution and fish …
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SERS-active peptide nanoparticles for investigating protein allostery and bionanoassembly
… assay for identifying novel binding ligands. SERS (Surface enhanced Raman scattering) - active nanoparticles, functionalized with a p53 peptide mimic, peptide 12.1, display biologically specific aggregation following addition of MDM2. The extent of nanoparticle assembly is altered following …
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Study of SERS for the detection of drugs of abuse
… the use of Surface Enhanced Raman Spectroscopy (SERS) for the detection of illicit drugs in oral fluid using metal enhancement mechanisms was undertaken. Initial work investigated ecstasy tablet composition using Raman to identify what drugs and excipients might be present in oral fluid samples …
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QUANTITATIVE DETECTION OF LIVER-RELEVANT BIOMARKERS BY SERS-IMMUNOLABALED GOLD NANOPARTICLES
Lab-on-a-chip technology has the potential to rapidly change the way experiments are conducted in a variety of fields ranging from medicine to environmental science. Specifically, sensors, detectors, and monitoring devices are increasingly being miniaturized to perform many experiments or …
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Untersuchungen an biologischen Proben mit verschiedenen Raman- und SERS-spektroskopischen Techniken
… wurde zum einen mit einer Glasfasersonde, zum anderen mit einer optischen Gradientenfalle kombiniert. Beide Ansätze wurden getestet und mit ihnen biologische Fragestellungen bearbeitet. Die Empfindlichkeit biologischer Proben und die geringe Konzentration ihrer Inhaltsstoffe macht …
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Investigation and design of SERS active nanoparticle assemblies via biological interactions
… different types of biological interactions using SERS has come to the forefront of this research. Novel nanotag synthesis has been detailed using a one-step functionalisation methodology. The stability of these nanotags has been investigated and found to be on par with the stability achieved using …
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Scalable Electrochemical Surface Enhanced Raman Spectroscopy (EC-SERS) for bio-chemical analysis
Conducting vertical nanopillar arrays can serve as three-dimensional nanostructured electrodes with improved performance for electrical recording and electrochemical sensing in bio-electronics applications. However, vertical nanopillar-array electrodes made of inorganic conducting materials by …
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