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Showing 1 to 20 of 20 for “"Rous sarcoma virus"”.
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Genetic and Biochemical Analysis of the Bryan Strain of Rous Sarcoma Virus
<p>Integration of Rous sarcoma virus DNA into its host genome was analyzed under conditions where secondary integration via virus spread was inhibited. This was accomplished by using the noninfectious pol<sup>-</sup>, env<sup>-</sup> alpha variant of the Bryan high titer strain of Rous sarcoma …
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The Phenotypic and Partial Biochemical Characterization of Unique Transformation Mutants of Rous Sarcoma Virus
Made available in DSpace on 2014-12-14T15:38:04Z (GMT). No. of bitstreams: 1 8008959.pdf: 4905675 bytes, checksum: 6a64c4d4e7542c50195f47b46ebd4707 (MD5) Previous issue date: 1979
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Studies on Adenylate Cyclase in Normal and Rous Sarcoma Virus Transformed Chicken Embryo Fibroblasts
Made available in DSpace on 2014-12-14T04:27:47Z (GMT). No. of bitstreams: 1 7915352.pdf: 8063286 bytes, checksum: 7ce27a88929613339fbfd3db64581ec7 (MD5) Previous issue date: 1979
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Tyrosine-Specific Protein Phosphorylation in Cells Transformed by Rous Sarcoma Virus or Stimulated by Mitogens
The transforming proteins of several RNA tumor viruses as well as a number of membrane receptors for polypeptide growth factors possess a tyrosine-specific protein kinase activity. Genetic and biochemical evidence indicates that this enzymatic activity is involved at the early stages of oncogenic …
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CROSS-REACTIVITY BETWEEN MAJOR HISTOCOMPATIBILITY COMPLEX ANTIGEN AND ROUS SARCOMA VIRUS-INDUCED TUMOR ANTIGEN IN CHICKENS
… histocompatibility complex (MHC) antigen and Rous sarcoma virus (RSV)-induced tumor associated antigen (TAA) in chickens was investigated. The B erythrocyte allcantigen locus was the genetic marker for the MHC. B2B2 and B5B5 chickens from crosses of highly inbred lines 6-1 and 15-1 and B24B24 …
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Studies on Cell Surface Function and Structure in Normal and in Rous Sarcoma Virus Transformed Cells
Made available in DSpace on 2014-12-14T07:14:39Z (GMT). No. of bitstreams: 1 7524315.pdf: 4584155 bytes, checksum: 8455e8d06b00992d004a353e99ad8c13 (MD5) Previous issue date: 1975
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Fine Structure of Chick Embryo Cells Differentiating in Vitro With Observations on Cultures Infected With Rous Sarcoma Virus
Made available in DSpace on 2014-12-09T20:34:25Z (GMT). No. of bitstreams: 1 6612436.pdf: 5793734 bytes, checksum: f2b8945375c734df308de9e7ee848fca (MD5) Previous issue date: 1966
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Studies on the Activity of the Long Terminal Repeat of Rous Sarcoma Virus in Animal Cells and in Yeast
<p>Transcription from the Rous sarcoma virus (RSV) Long terminal repeat (LTR) in untransformed rat 3Y1 fibroblasts is dependent on the presence of serum. Within an hour of addition of serum to a serum-deprived culture there is a 5 fold stimulation in the level of transcripts initiated at the LTR. …
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Potassium and Sodium Movements Related to Growth State and Malignant Transformation in Cultured Chicken Embryo Cells
… in growing normal, density-inhibited, and Rous sarcoma virus-transformed (RSV-transformed) chicken embryo fibroblasts and following serum stimulation of quiescent, density-inhibited chicken embryo fibroblasts. Active potassium transport and the associated specific ouabain binding were shown …
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MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) VS NON-MHC INFLUENCES ON RESPONSE TO RSV-INDUCED TUMORS IN CHICKENS
… to exert a decisive influence on the fate of Rous sarcoma virus (RSV)-induced tumors. However, noninbred chickens with identical B genotypes and inbred lines indistinguishable at the MHC have demonstrated considerable variation in response to RSV challenge. The major objective of this research …
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INFLUENCE OF GENOTYPE, PROTEIN-CALORIE RESTRICTION AND THEIR INTERACTION UPON RSV-INDUCED TUMORS IN CHICKENS
… by nutritional restriction interaction upon Rous sarcoma virus (RSV)-induced tumor development in chickens. Two genetic systems were used. The first involved an inbred line and a noninbred line of chickens. The second utilized F2 generation progeny from a cross of lines 6-1 and 15-1, highly …
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The effects of erythrocyte alloantigen L on the avian immune response
… 1 examined the alloantigen system L effects on Rous sarcomas in three B complex genotypes. The parental stock were 50% Modified Wisconsin Line 3 and 50% inbred Line 6.15- 5. B2B5 L1L2 x B2B5 L 1L2 matings produced experimental chicks. Chicks were inoculated with 20 pock-forming units (pfu) Rous …
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Molecular modeling and simulations of viruses: structure, dynamics and antibody design
… to investigate the dynamic properties of virus capsids, to determine the atomic structure of highly-flexible capsid domains, which could not be solved using a single experimental method, and to unravel the molecular mechanisms of host-pathogen interactions. Furthermore, we have recently …
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Purification and Activity of the PP60SRC Protein Kinase
<p>Transformation of cells by Rous Sarcoma virus results from the action of a single virally coded phosphoprotein with a molecular weight of 60,000 daltons (pp60<sup>src</sup>). The expression of pp60<sup>src</sup> results in many significant changes in the cell's phenotype which include disruption …
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Strategies for Oncogenesis by Avian Leukosis Viruses
<p>The mechanism of oncogenesis by avian leukosis viruses (ALVs) was examined. ALVs are slowly transforming RNA tumor viruses that do not transform cells in tissue culture and that cause neoplastic disease only after a latent period of 4-12 months. ALVs generally induce widely disseminating B cell …