Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"RECIST"”.
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Vergleich unidimensionaler, bidimensionaler und volumetrischer Messverfahren unter Anwendung eines 64-Zeilen-Mehrschicht-CTs am Beispiel von Bronchialkarzinomen und pulmonalen Metastasen
… vorliegenden Arbeit wurden die unidimensionale RECIST-Methode, das bidimensionale WHO-Verfahren und die Volumetrie mittels Region Growing verglichen. 64 selektierte Patienten mit pulmonalen Läsionen erhielten mittels eines 64-Zeilen-Spiralcomputertomographen insgesamt 276 CTs, anhand derer …
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Temozolomide and Bevacizumab Therapy In Advanced Hemangiopericytoma/ Solitary Fibrous Tumor
… as first- or second-line therapy, the overall RECIST response rate was 0%. Most patients achieved a brief duration of disease stabilization on chemotherapy, with median progression-free survival (PFS) period of 4.6 months. For the 14 patients with advanced HPC/SFT who received temozolomide and …
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Biologically Interpretable Representation Learning for Mechanistic Insights into Cancer Immunotherapy Resistance
… and expose heterogeneity within standard RECIST categories. Overall, this work presents a novel, interpretable framework for modeling ICI response, offering insights into resistance mechanisms and actionable paths for biomarker discovery, patient stratification, and therapeutic innovation …
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The dynamics of the serum concentration of CEA, CA15-3 and CA19-9 and survival in patients treated for advanced breast and colorectal cancer. The determination of the prognostic correlates of changes in tumour markers CEA, CA15-3 and CA19-9 during chemotherapy treatment for advanced breast and colorectal cancer.
… This provides valuable information because RECIST criteria can delay radiological identification of disease progression compared with WHO criteria [6, 7] and new therapies may act to stabilise tumour growth rather than reduce it [8].
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EGFR in Early Non-small Cell Lung Cancer: Tyrosine Kinase Inhibition in a Neoadjuvant Trial
… was seen in 43% of patients, with 11% achieving RECIST partial response (PR). Analysis of molecular markers showed EGFR TKD mutations in 17% of cases, being the only associated with PR. For the first time we defined the histopathological response of NSCLC to these agents, characterized by …
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Valutazione della terapia chirurgica con resezione e ricostruzione vascolare e della terapia oncologica nei carcinomi della tiroide localmente avanzati
… lesioni è stata effettuata seguendo i criteri RECIST. L'analisi dei dati ha mostrato che vi è differenza statisticamente significativa solo tra la PFS (Progression Free Survival) del braccio di controllo e quella del braccio sperimentale a favore del braccio sperimentale (p=0.0399), ma …
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Radiotherapy for head and neck paragangliomas: A 10 year retrospective review 2005-2014 at Groote Schuur Hospital and UCT Private academic hospital
… of local tumour control was performed using RECIST criteria and the KaplanMeier method. 69% of patients received 14-16gy in 1-3 fractions while 31% received 48- 50gy in 25 fractions. Radiation-associated toxicity was graded according to the commonly used Radiation therapy Oncology group …
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Quantitative Non-Contrast Perfusion Measurements Using Arterial Spin Labeled MRI: Evaluation of Therapy Response in Brain Tumors and Technical Advancements in Kidneys
… Response Evaluation Criteria in Solid Tumors (RECIST) or the modified Response Assessment in Neuro-Oncology (RANO), primarily focus on measuring tumor size changes for treatment response assessment. However, these conventional techniques may not detect early therapy responses, as many cancer …
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Voxel-Level Absorbed Dose Calculations With A Deterministic Grid-Based Boltzmann Solver For Nuclear Medicine and The Clinical Value of Voxel-Level Calculations
… 70% of volume (D70) predicted binary modified RECIST response with an area under the curve of 80.3%. A D70 88 Gy threshold yielded 89% specificity and 69% sensitivity.</p> <p>The GBBS was shown to be fast and accurate, flaws in clinical dosimetry models were highlighted, and dose-response …
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Development of imaging techniques to assess tumour cell death
… (Response Evaluation Criteria in Solid Tumours (RECIST)). More recently these assessments have also included functional and molecular information, as these parameters can show earlier responses to chemotherapies, e.g. using PET measurements of 2-[¹⁸F]-fluoro-2-deoxy D-glucose uptake (FDG-PET). …
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Challenges facing clinical trial design in oncology
… response evaluation criteria in solid tumours (RECIST) needs to be applied to quality of life tools and the inclusion of correlative tests. It is important to consider and specify the statistical rationale for these aspects of trial design. As investigators we need to remain accountable for each …