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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 37 for “"Quantitative Phase Imaging"”.
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Quantitative phase imaging for cellular biology
… the ability to measure a large number of cells. Quantitative phase imaging (QPI) is an emerging field that addresses this need. New quantitative phase imaging modalities have emerged that provide highly sensitive information on cellular growth, motility, dynamics and spatial organization. These …
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Quantitative phase imaging for blood cytometry
… smear analysis technique known as Diffraction Phase Cytometry (DPC), which is capable of providing the same information on red blood cells as is provided by current clinical analyzers, while rendering additional, currently unavailable parameters on the 2D and 3D morphology of individual red …
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Applications of quantitative phase imaging for pathology
… of a wide-spread screening program. Quantitative phase imaging (QPI) of unstained tissue provides information on the refractive index distribution, or tissue morphology, with nanometer level sensitivity. Subtle morphological changes in both the epithelial and stromal regions of …
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High throughput platform for multiscale quantitative phase imaging
Quantitative phase imaging (QPI) yields the spatial phase map of the object’s scattering potential. QPI has enabled unprecedented label-free studies in biomedicine, ranging from cell dynamics and growth to cancer diagnosis and prognosis. The field is currently transitioning from technology-driven …
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Real-time quantitative phase imaging for cell studies
… have been developed to improve contrast in cell imaging, including use of exogenous contrast agents such as fluorescence microscopy, as well as utilizing properties of light-specimen interaction for optics design, to reveal the endogenous contrast, such as phase contrast microscopy (PCM) and …
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Prostate tissue diagnosis using quantitative phase imaging techniques
Restriction data tranferred 2014-07-01T11:20:34-05:00 Original Data Group with Access UIUC Users [automated] Release Date: 2015-08-22 11:49:27 UTC Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system
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Label-free breast histopathology using quantitative phase imaging
… analysis methods for automated diagnosis. A quantitative, label-free and automatable microscopic modality for breast cancer diagnosis is, thus, needed to address these shortcomings in the standard method. Furthermore, prognostic biomarkers are important tools used by clinicians in order …
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Quantitative phase imaging : a study from 2D to 3D
In this thesis, quantitative phase imaging (QPI) techniques including 2D and 3D versions are investigated and presented. With QPI, biophysical and biochemical information of transparent biological micro-specimens can be measured and quantified. 2D quantitative phase maps of cell samples on the one …
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Label-free Photothermal Quantitative Phase Imaging with Spectral Modulation Interferometry
… can be measured as an optical pathlength or phase change. When a chemical species in a sample absorbs optical energy at a particular wavelength, this absorption raises the temperature at these points in the sample via the photothermal effect. This temperature change changes the local …
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Quantitative phase imaging: advances to 3D imaging and applications to neuroscience
This thesis provides a brief overview of quantitative phase imaging (QPI) methods along with applications and advances made on them. First, spatial light interference microscopy (SLIM) is introduced as a QPI method extensively used in this thesis. Using this setup, an application of QPI in …
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High-sensitivity Full-field Quantitative Phase Imaging Based on Wavelength Shifting Interferometry
Quantitative phase imaging (QPI) is a category of imaging techniques that can retrieve the phase information of the sample quantitatively. QPI features label-free contrast and non-contact detection. It has thus gained rapidly growing attention in biomedical imaging. Capable of resolving biological …
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Spectral domain interferometry: A high-sensitivity, high-speed approach to quantitative phase imaging
… bright field microscopes. Therefore, the phase-based optical microscopy techniques play important roles in the development of the modern biomedical science. Furthermore, the ability to achieve quantitative phase measurement of the tiny structures of biomedical specimens is of great …
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Spectral-domain optical coherence phase microscopy for quantitative biological studies
Conventional phase-contrast and differential interference contrast microscopy produce high contrast images of transparent specimens such as cells. However, they do not provide quantitative information or do not have enough sensitivity to detect nanometerlevel structural alterations. We have …
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Novel methods for recording and reconstructing images in digital holographic microscopy
… in the development of several specialized imaging techniques that can enhance the contrast of subcellular features without the need for labeling. Examples include phase contrast, differential interference microscopy, dark field microscopy, and Rheinberg illumination. However, these …
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Quantitative phase microscopy for the study of electromotility in living cells
… cells. We describe here our development of a quantitative phase microscopy technique that is capable of detecting the intrinsic changes induced by electric activity in a human cell line. Chapter 1 provides introductory material regarding cellular electrophysiology and a review of the …
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Phase imaging with computational specificity for cell biology applications
Recent advancements in quantitative phase imaging (QPI) and deep learning have opened up an exciting frontier. It has been shown that deep learning methods, with their ability to extract intricate structures from massive raw datasets, can be applied to both interpreting QPI measurements of …
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Gradient light interference microscopy for imaging strongly scattering samples
… broadband optical fields in conjunction with phase-shifting interferometry to extract high-resolution and high-contrast structures from otherwise cloudy images. We construct our system from a differential interference contrast microscope, demonstrating our new modality in transmission and …
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Computational phase imaging based on intensity transport
Light is a wave, having both an amplitude and a phase. However, optical frequencies are too high to allow direct detection of phase; thus, our eyes and cameras see only real values - intensity. Phase carries important information about a wavefront and is often used for visualization of biological …
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Neural Networks For Phase Demodulation In Optical Interferometry
… NNs to optical interferometry for the purpose of quantitative phase imaging (QPI). We show that NNs are capable of quantifying the optical pathlength difference in an interferogram with sensitivities that achieve the fundamental limit given by the Cramér-Rao bound (CRB). As an application, we …
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High Resolution Phase Imaging using Transport of Intensity Equation
Quantitative phase Imaging(QPI) has emerged as a valuable tool for imaging specimens with weak scattering and absorbing abilities such as cells and tissues. It is complementary to fluorescence microscopy, as such, it can be applied to unlabelled specimens without the need for fluorescent tagging. …
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