Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 148 for “"Prokaryotes"”.
-
Greenhouse gas metabolizing prokaryotes in peatlands
Peatlands in the northern hemisphere store substantial amounts of carbon and nitrogen, and are predicted to react sensitively to global warming. The main objective of the study was to study microbial processes involved in the fluxes of the greenhouse gases methane (CH4) and nitrous oxide (N2O) from …
-
Conservation of Translation Initiation Between Prokaryotes and Eukaryotes
… mechanism that can initiate translation in both prokaryotes and eukaryotes. Colussi et al. (2015) reported that the eukaryotic PSIV IGR IRES can initiate prokaryotic translation and effectively circumvent domain-specific divergences. This novel discovery led us to investigate whether this IRES is …
-
Identifying The Structure Of Genomic Islands In Prokaryotes
… that have a fundamental role in the adoption of prokaryotes and the impact of the species on the environment. Previous computational biology research has focused on developing tools that detect GIs in prokaryotic genomes, while there is little research investigating GI structure. This research …
-
Reconstructing gene function and gene regulatory networks in prokaryotes
The ability of a bacterial cell to respond to a complex environment lies with the network of genetic interactions that process information regarding the state of the cell and its local environment. The object of this study has been to better understand bacterial genetic regulatory networks, which …
-
GENOME-WIDE IDENTIFICATION OF RNA SENSORS IN PROKARYOTES AND EUKARYOTES
RNA's ability to fold into complex secondary and tertiary structures underlies its suitability as cellular sensors that detect and respond to metabolite changes in the environment. Here, we introduce a high-throughput strategy named PARCEL that directly and experimentally identifies RNA sensors …
-
Restriction-Modification and CRISPR-Cas Systems: Cooperation Between Innate and Adaptive Immunity in Prokaryotes
… most common bacterial defense systems. However, prokaryotes have been shown to harbor a multitude of other putative antiphage defense systems, which can often exist together in a single host. I predict that future studies will likely uncover many more fascinating instances of immune interaction …
-
Modelling evolution of genome size in prokaryotes in response to changes in their abiotic environment
The size of the genomes of known free-living prokaryotes varies from � 1:3 Mbp to � 13 Mbp. This thesis proposes a possible explanation of this variation due to variability of the physical conditions of the environment. In a stable environment, competition for the resource becomes the main force of …
-
Patterns of Two Types of Overlapping Genes in Five Mammalian Genomes
… eukaryotic genomes too and are not restricted to prokaryotes alone. Here we determined overlapping genes in a set of orthologous genes in the genomes of human, chimp, mouse, rat, and dog and contrasted the patterns of overlapping between two principal types of overlapping genes, the …
-
Genetic and Computational Tools for Engineering Complex Prokaryotic Systems
… available for gene editing and regulation in prokaryotes, emphasizing recent innovations that offer precise and flexible control over gene expression. Building on this foundation, we engineered interconnected CRISPRa/i circuits capable of executing dynamic genetic programs in both cell-free …
-
A Bioinformatics Approach to Identifying Radical SAM (S-Adenosyl-L-Methionine) Enzymes
… on oxygen tolerances were more apparent in prokaryotes than in eukaryotes. Although eukaryotes tend to have fewer radical SAM enzymes than prokaryotes, we were able to analyze uncharacterized radical SAM enzymes from both an aerobic eukaryote (Entamoeba histolytica) and a eukaryote capable …
-
Control of Substrate Supply to the Chloroplast 2-C-methyl-D-erythritol-4-phosphate Pathway
… this metabolic shunt is instead restricted to prokaryotes, most commonly proteobacteria. Crucially, it was not part of the central metabolism of the cyanobacterial ancestors of plastids, resulting in the absence of key ED pathway genes in endosymbiont genomes of plants. This conclusion partly …
-
Recovery and quality estimation of metagenomic assembled genomes of eukaryotes
… while the majority of microorganisms are often prokaryotes, by biomass there are suspected to be 6 times more prokaryotes than fungi globally (Bar-On et al., 2018), eukaryotes are also important constituents of microbial communities (e.g on the human skin). Shotgun metagenomics can provide …
-
Natural selection on MRNA secondary structure and its correlation with protein functional groups
… on the complete sets of genes of a number of prokaryotes and eukaryotes. Two types of randomized experiments were performed on each genetic data set, providing an independent confirmation of the results. In the first method of randomization, synonymous mRNAs were generated for each gene, …
-
Structural Characterization of the Transfer Ribonucleic Acids From Halobacterium Volcanii and Other Archaebacteria
… primary kingdom, distinct from the eubacteria ('prokaryotes') and the eucaryotes. To help in evaluating the molecular affinities, we characterize here the transfer RNAs (tRNAs) in two ways. First, we describe the modification patterns of the tRNAs of ten archaebacteria (Halobacterium volcanii, …
-
Exploring Prokaryotic Thiamin Biosynthesis: Mechanistic Studies On Thiamin Thiazole Synthase And Pyrimidine Synthase
… of thiazole and pyrimidine are different in prokaryotes versus eukaryotes. Understanding of thiamin biosynthesis is still incomplete and a lot of new discoveries relating to the enzymes in its biosynthesis have been explored in depth revealing new mechanisms and enzymology. In prokaryotes, …
-
A nucleic acid-based bacterial message export system for cell-to-cell communication
… within natural systems of eukaryotes and prokaryotes typically entails message transmission between and among cells via small-molecule messengers being funneled from the sender to the receiver cell. Nucleic acids are rarely used as extracellular messengers due to their labile nature and …
-
HORIZONTAL GENE TRANSFER (HGT) AND SPHAGNUM FALLAX: A PHYLOGENETIC LOOK INTO THE OCCURRENCE, PREVALENCE, AND IMPORTANCE OF HORIZONTAL GENE TRANSFER IN A BOG MOSS
… in nature. HGT occurs frequently between prokaryotes and plays a significant role in prokaryotic evolution. This process is also known to occur between symbiotic bacteria and their eukaryotic hosts, but less is known about HGT between eukaryotes and the role that this type of transfer may …
-
Evolutionary Analysis of Large-Scale Genomic Changes
… resolve both shallow and deep relationships of prokaryotes and eukaryotes, including the genus Prochlorococcus, the methanogens, and five mammalian orders. A computational pipeline was developed to construct distance-based gene order trees. The resulting gene order phylogeny was consistent and …
-
The Mechanism of Copper Toxicity in Escherichia Coli
… toxicity. Copper is toxic to both eukaryotes and prokaryotes and is the causative agent of Indian childhood cirrhosis, Tyrolean infantile cirrhosis, and Wilson disease. Studies in eukaryotic systems demonstrated that copper-toxified cells had elevated levels of DNA damage and oxidative stress. …
-
Glutamine synthetase in Bacteroides fragilis
… vital to the growth of the organism and many prokaryotes are known to possess two or more isoforms of the enzyme. In addition, GS expression and regulation is usually tightly regulated in concert with the availability of nitrogen. Previous studies have identified a single GSIII encoding gene …
Page 1 of 8