Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 15 of 15 for “"Population Screening"”.
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Universal Lynch Syndrome Screening in Newly Diagnosed Colorectal Cancer: Impact of an Alberta-wide Screening Program
… germline genetic testing. Universal tumor screening in all new CRCs using Immunohistochemistry (IHC) to assess for loss of MMR-protein expression allows for identification of individuals at increased risk for underlying LS who would benefit from genetic testing. This thesis reports the …
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Women Living with HIV/AIDS and Disclosure
… WLWHA are a hard-to-reach, vulnerable population. Screening and intervention strategies may be key to disclosure. Further research is needed to facilitate disclosure, improve access and retention in care, and optimize health care outcomes potentially lowering health costs and producing …
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The Role of Proteomics in Colorectal Cancer Biomarker Discovery
… of the disease render CRC a suitable model for population screening. Current screening modalities have proven utility but they lack sensitivity and specificity, and thus there is a need to develop non-invasive tests to detect and stage the disease. Biomarkers are gaining popularity as they …
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Papel das calcificações vasculares mamárias na predição do risco cardiovascular
… (MMG) is the only method available for population screening of breast cancer, but also could identify the atherosclerosis process, referred to as breast vascular calcification (BVC). We verified if there is an association between the BVC and CCS, thus predicting cardiovascular risk (CVR) …
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Knowledge, attitudes and practices regarding cervical cancer screening among women attending Tshilidzini Hospital, Limpopo Province
… the developing world, due to a lack of effective population screening. Although cervical cancer screening is an effective method for the reduction of the incidence and mortality of the malignancy, the unfortunate observation on the ground is that the screening attendance rate at Tshilidzini …
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Evaluation of a stage II screening protocol for prostate cancer
… cause of cancer death in Canada. During PCa population screening, approximately 25% of patients with a normal digital rectal examination (DRE) and intermediate serum prostate specific antigen (PSA) level have PCa. Since all patients typically undergo biopsy, it is expected that approximately …
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Analytics for Improved Cancer Screening and Treatment
… for advanced cancers and to identify effective screening strategies for detecting early-stage disease. In Part I, we propose a methodology for designing combination drug therapies for advanced cancer, evaluating our approach using advanced gastric cancer. First, we build a database of 414 …
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Artifact removal in digital retinal images
… much as 20% of retinal images collected in the population are affected by artifacts, that render them ungradable both by expert graders and by the more recent automatic grading systems.;This work aims to develop an artifact removal strategy able to improve the effectiveness of retinal image …
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Automated analysis of digital medical images in cervical cancer screening: A systematic review
… high income countries, due to lack of organized population screening. Cervical cancer screening is the best way to detect lesions and remove them before they advance into malignancy. In South Africa, the current standard cervical cancer screening protocol begins with cytology examination then a …
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Assessment of factors associated with diabetic retinopathy among diabetic patients in Zambia
… diabetic patients that attended the retinopathy-screening program between April 2012 and September 2012 were eligible for the primary study. The secondary data analysis was restricted to patients 18 years and older. Data analysis was carried out by R version 3.3.1. The characteristics of the …
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An analysis of the utility of quantitative faecal immunochemical tests in screening and symptomatic populations
… in 4 large randomised control trials (RCT), that screening for colorectal cancer (CRC) using annual or biennial guaiac faecal occult blood tests (gFOBT) reduces mortality and incidence. The faecal immunochemical test (FIT) uses technology that is analytically more sensitive and specific for human …
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Insights into breast cancer: New familial patterns and identification of a potential predictive marker
… can develop. Women age 40 and older are offered screening mammography. However, population screening is expensive, and being able to pinpoint those who are at high risk of breast cancer would be beneficial. Both genetic and environmental risk factors could be used to select women who need …
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Monogenic diabetes in large population settings
In this thesis we aim to utilise large population cohorts to analyse monogenic diabetes. This will involve gene discovery searching for novel disease genes and variants, assessing the penetrance and comorbidities risk in carriers of pathogenic monogenic diabetes variants, and studying disease …
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Biomarker development for gastrointestinal and ovarian cancer: a proteomic approach
… for cancer patients would be advantageous in population screening for the early detection of cancers, pathological diagnosis, assessment of prognosis, tailoring treatment to individuals, and assessment of treatment response. With this in mind different proteomic approaches were used to …
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The performance and feasibility of three brief alcohol screening tools in a senior population
Screening is the first step in identifying and treating alcohol-related problems among the senior population. This study was designed with two purposes. The first was to cross-validate the Senior Alcohol Misuse Indicator (SAMI) with two commonly used screening tools - the CAGE and the Shortened …