Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 23 for “"Phase microscopy"”.
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Chip-scale diffraction phase microscopy
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2024-05-01
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Diffraction phase microscopy for applications in materials science
Quantitative phase imaging (QPI) is a flourishing new field which has recently found tremendous success in the life sciences. QPI utilizes not only the amplitude of the imaging field, but also its phase, in order to provide quantitative topographical and/or refractive index data. As fields from the …
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Spectral-domain optical coherence phase microscopy for quantitative biological studies
Conventional phase-contrast and differential interference contrast microscopy produce high contrast images of transparent specimens such as cells. However, they do not provide quantitative information or do not have enough sensitivity to detect nanometerlevel structural alterations. We have …
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Quantitative phase microscopy for the study of electromotility in living cells
… describe here our development of a quantitative phase microscopy technique that is capable of detecting the intrinsic changes induced by electric activity in a human cell line. Chapter 1 provides introductory material regarding cellular electrophysiology and a review of the literature on the …
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In situ Nanoscale Quantification of Corrosion Kinetics by Quantitative Phase Microscopy
… presented a novel application of a quantitative phase microscopy technique, spectral modulation interferometry (SMI), for in situ nanoscale characterization of corrosion of different alloys in real-time. SMI offers high sensitivity, rapid image acquisition, and speckle-free images; thus, …
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Pathophysiology of human red blood cell probed by quantitative phase microscopy by YongKeun Park.
There is a strong correlation between the membrane fluctuations and the material properties of living cells. The former, consisting of submicron displacements, can be altered by changing the cells' pathophysiological conditions. It is our hypothesis that the material properties of cells can be …
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Real-time quantitative phase imaging for cell studies
… exogenous contrast agents such as fluorescence microscopy, as well as utilizing properties of light-specimen interaction for optics design, to reveal the endogenous contrast, such as phase contrast microscopy (PCM) and differential interference contrast (DIC) microscopy. Although PCM and DIC …
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Optical imaging with machine learning for the automated characterization of micro- and nanoscale devices
… with standard optimization algorithm(s). Two phase retrieval techniques are compared: diffraction phase microscopy (DPM) and transport of intensity (TIE). TIE is modified for low intensity and zero intensity images. Modified TIE is optimized for theoretical analysis of Gaussian mode phase …
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The impact of improved materials in poly(vinyl chloride)-based endotracheal tubes
… year and are known to invoke the proliferative phase in the cell linings. The technical objective of this work was to investigate in vitro the interaction between epithelial cells and current poly(vinyl chloride)-based ET materials, as well as some ET samples embedded with materials intended to …
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Wide-field structured illumination microscopy for fluorescence and pump-probe imaging
The optical resolution of microscopy is limited by the wave-like characteristic of the light. There are many recent advances in overcoming this diffraction limited resolution, but mostly focused on fluorescent imaging. Furthermore, there are few non-fluorescence wide-field super-resolution …
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Quantitative phase imaging : a study from 2D to 3D
In this thesis, quantitative phase imaging (QPI) techniques including 2D and 3D versions are investigated and presented. With QPI, biophysical and biochemical information of transparent biological micro-specimens can be measured and quantified. 2D quantitative phase maps of cell samples on the one …
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Functional Spectral Domain Optical Coherence Tomography Imaging
… non-invasive backscattering amplitude and phase from a sample. Due to the translucent nature of the tissue, ophthalmic imaging is an ideal space for SDOCT imaging. </p><p>Structural imaging of the retina has provided new insights into ophthalmic disease. The phase component of SDOCT images …
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Quantitative anisotropy imaging with polarized interference microscopy
… developed, such as fluorescence polarization microscopy(FPM), liquid crystal based polarization microscopy (LC Polscope), polarization state optical coherence tomography (ps OCT), and polarization Raman spectroscopy. Quantitative phase microscopy (QPM) is another important modality of optical …
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In vivo imaging and morphogenesis of butterfly scale development
… surgery techniques and adapted quantitative phase microscopy methods to achieve label-free, in vivo visualization of scale cell growth in Vanessa cardui pupae throughout pupal development. This continuous visualization of scale cells establishes a clear phenomenological timeline of scale …
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Label-free Photothermal Quantitative Phase Imaging with Spectral Modulation Interferometry
… can be measured as an optical pathlength or phase change. When a chemical species in a sample absorbs optical energy at a particular wavelength, this absorption raises the temperature at these points in the sample via the photothermal effect. This temperature change changes the local …
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Development of predictable palladium based optomechanical hydrogen sensors
… in thin palladium films using quantitative phase imaging techniques, so that a new sensor could be designed and accurately modelled. This second fabricated sensor consisted of a Pd coated cantilever which operated based on optical probing of mechanical deflections. For more thorough …
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Machine Learning for Sepsis Prognosis: Prediction Models and Dissecting Electronic Health Records
… neutrophil function from simple-to-obtain phase microscopy images. I developed an experimental pipeline using measurement of reactive oxygen species genera=on as a label of neutrophil function. I generated a large neutrophil imaging dataset and explored different deep learning approaches to …
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Single-shot quantitative interferometric microscopy for imaging high-speed dynamics
… these high-speed dynamics, we need optical microscopy methods having millisecond temporal resolution, submicron spatial resolution and the capability of quantitative imaging. However, current imaging techniques usually either could only offer qualitative imaging, or has low quantitative …
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High-sensitivity Full-field Quantitative Phase Imaging Based on Wavelength Shifting Interferometry
Quantitative phase imaging (QPI) is a category of imaging techniques that can retrieve the phase information of the sample quantitatively. QPI features label-free contrast and non-contact detection. It has thus gained rapidly growing attention in biomedical imaging. Capable of resolving biological …
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High throughput platform for multiscale quantitative phase imaging
Quantitative phase imaging (QPI) yields the spatial phase map of the object’s scattering potential. QPI has enabled unprecedented label-free studies in biomedicine, ranging from cell dynamics and growth to cancer diagnosis and prognosis. The field is currently transitioning from technology-driven …
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