Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 440 for “"Phase II"”.
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Crab flare observations with H.E.S.S. phase II
… measures very high energy (VHE) gamma-rays. In Phase I, the array started data taking in 2004 with its four identical 13 m telescopes. Since then, H.E.S.S. has emerged as the most successful IACT experiment to date. Among the almost 150 sources of VHE gamma-ray radiation found so far, even the …
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Relationship Between Flavonoid Structure And Phase-II Metabolism
Objective: The overall objective is to develop structure-metabolism relationships (SMRs) between UGTs and flavonoids for predicting glucuronidation of flavonoids. The goals of this research project were to: 1) identify the major UGT isoform(s) contributing to the glucuronidation of flavonoids and …
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Curtailed phase II binary outcome trials and adaptive multi-outcome trials
Phase II clinical trials are a critical aspect of the drug development process. With drug development costs ever increasing, novel designs that can improve the efficiency of phase II trials are extremely valuable. Phase II clinical trials for cancer treatments often measure a binary outcome. The …
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Leveraging Technology to Add Value to a Phase II NPDES Permit
In 1999, Phase II of the National Pollutant Discharge Elimination System engaged operators of small Municipal Separate Storm Sewer Systems (MS4) in the control of runoff from urban areas. The complex task of urban runoff mitigation has been investigated for several decades, resulting in a large …
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Innovative Methods for the Design and Analysis of Phase II Clinical Trials
… clinical trial designs, particularly for phase II trials, which play a critical role in the drug development process. Innovative methods are especially necessary for addressing key challenges in phase II trials in terms of dose-ranging study, patient population selection, and decentralized …
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A nonparametric change point model for multivariate phase-II statistical process control.
Phase-II statistical process control (SPC) procedures are designed to detect a change in distribution when a possibly never-ending stream of observations is collected. Extensive study has been conducted with the purpose of detecting a shift in location (e.g. mean or median) when univariate …
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GVWD corrosion control initiative, phase II: inhibitor chemical testing at Seymour Dam
Greater Vancouver Regional District (GVRD) waters have some of the highest corrosion potentials in North America. A previous pilot study determined that copper corrosion could be reduced by 60 to 80 percent and lead corrosion could be reduced by10 to 60 percent by disinfecting with chloramine …
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Social support comparisons between men and women in phase II cardiac rehabilitation
… well-being during the rehabilitative phase. The type and amount of social support the cardiac patient perceives may affect participation in cardiac rehabilitation. The purpose of this study was to 1) determine if there was a difference between the amount of social support perceived by …
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Developing a Mechanistic Understanding and Optimization of the Cannibal Process: Phase II
… the solids destruction in the system. The first phase of this study has looked at the effect of three different HRTs, 5 day, 7 day and 10 day. The interchange rate during phase I was 10%. The results showed that the 7 day HRT can be recommended as the minimum retention period for the Cannibal …
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Characteristics and contributory causes related to large truck crashes (phase-II) - all crashes
… related to large-truck crashes. During the first phase of this study, fatal crash data from the Fatality Analysis Reporting System (FARS) database were studied to achieve that objective. In this second phase, truck-crashes of all severity levels were analyzed with the intention of understanding …
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A hybrid analysis approach to the high energy stereoscopic system phase II mono-analysis
The High Energy Stereoscopic System (H.E.S.S.) is an array of imaging atmospheric Cherenkov telescopes located in the Khomas highlands of Namibia. Their primary purpose is to detect Cherenkov light (CL) produced by particles in extensive air showers which are produced by incident high energy …
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Informational Needs and Preferred Time to Receive Information for Phase II Cardiac Rehabilitation Patients
… determine at which time interval in the recovery phase patients wish to receive this information.</p>
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Basic Educational Experiences Program Utilizing Individualized Instruction in Auditory and Visual Perception Phase II
The purpose of this study was to develop Phase II in the Basic Educational Experiences Program, Phase I (6) of which was already in use in Yakima's Elementary Schools. Phase I was a minimal program in motor-sensory development. Phase II was a program in sequential perceptual activities contributing …
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Sulforaphan und Selen : Einfluss auf Phase II Enzyme und Selenoproteine sowie deren Effekt auf die entzündungsvermittelte Dickdarmkanzerogenese
… und Se auf die Aktivität sowie Expression von Phase II Enzymen und Selenoproteinen untersucht. Der Einfluss der Kombination von SFN und Se auf die unter physiologischen Bedingungen stattfindende Proliferation und Apoptose war ebenso Gegenstand der Arbeit wie die Modulation von …
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Phase II Trials Powered to Detect Activity in Tumor Subsets with Retrospective (or Prospective) Use of Predictive Markers
Classical phase II trial designs assume a patient population with a homogeneous tumor type and yield an estimate of a stochastic probability of tumor response. Clinically, however, oncology is moving towards identifying patients who are likely to respond to therapy using tumor subtyping based upon …
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Storm Water System Monitoring for the Small Municipality Under Phase II of the National Pollutant Discharge Elimination System
… Pollutant Discharge Elimination System (NPDES) Phase II requirements, small municipalities are responsible for storm water impacts on receiving waters within their jurisdiction. For the purposes of NPDES Phase II requirements, small municipalities are identified as these municipalities that are …
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A BIOMARKER ENRICHMENT PHASE II TRIAL OF 177LU-DOTATATE IN METASTATIC NASOPHARYNGEAL CANCER WITH A SAFETY RUN-IN
… We also report the initial results of our phase 2 therapeutic trial (NCT05198479) to study the efficacy of targeting SSTR2 with 177Lu-DOTATATE in metastatic NPC.
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An evaluation of the proposed IFRS 4 Phase II measurement methodology: the impact of South African life insurers
… key principles and likely impacts of the IFRS 4 Phase II standard, in its current proposed form, in the South African life insurance context. In particular, the proposed IFRS 4 Phase II approach to profit reporting is contrasted with the current Financial Soundness Valuation (FSV) approach for …
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Preparedness for end-of-life in patients with advanced metastatic cancer enrolled in a clinical trial (phase I/phase II)
… with advanced metastatic cancer enrolled in a phase I clinical trial have a life expectancy of less than nine months. Advance care planning (ACP) is a means of tailoring care to patients’ needs, especially at the end-of-life (EOL). An extensive review of literature identified a positive impact …
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Vom Antioxidanz zum Genregulator : transkriptionelle Regulation von Phase I- und Phase II-Enzymen durch Vitamin E und antioxidative sekundäre Pflanzeninhaltsstoffe
… wurden, auf die transkriptionelle Regulation von Phase I- und Phase II-Enzymen zu untersuchen. Dazu wurde die Aktivierung des PXR (pregnane X receptor) und des Nrf2 (NF-E2-related factor-2) als zentrale Transkriptionsfaktoren der Phase I- bzw. Phase II-Enzyme getestet. Der Einfluss von …
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