Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 132 for “"Patient Outcome"”.
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Does the Timing of Adjuvant Chemotherapy for Gastric Cancer Influence Patient Outcome?
… between surgery and the start of chemotherapy on patient outcome. Patients and METHODS: A retrospective review was conducted of 410 patients who underwent 5-fluorouracil/mitomycin-C/polysaccharide-K adjuvant chemotherapy for stage IIA-IIIC gastric cancer after curative resection. Overall survival …
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The Genetics of IBD: From Susceptibility to Drug Response and Patient Outcome
… around the world, IBD has a severe impact on patients’ quality of life. Several pharmacologic treatments have been available since the 1950s. However, the majority of patients either do not respond to a given therapy or lose response to a previously effective treatment and thus require …
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Comparison of patient outcome for aortic valve replacement verses transcatheter aortic valve replacement
… Food and Drug Administration (FDA) for use in patients who are not candidates for AVR or who are at high risk for AVR. The initial studies of TAVR showed an elevated risk of stroke in those undergoing surgery but it provided similar relief of symptoms, and similar patient mortality at one and …
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Effect of Short-Term Postoperative Celecoxib Administration on Patient Outcome After Outpatient Laparoscopic Surgery
… of celecoxib on pain management and recovery outcomes following laparoscopic surgery. Methods: Eighty consenting ASA I–III outpatients undergoing laparoscopic surgery were randomly assigned to one of two treatment groups: Control (placebo) or Celecoxib (celecoxib, 400 mg•day-1). The initial …
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Interleukin-6 and Interleukin-10 concentrations as predictors of patient outcome following major traumatic injury
… interleukin-10, may allow an early prediction of patient outcome and thelikelihood of developing complications. Blood samples and clinical data were taken on days 1, 3 and 5, with additional clinical datataken on day 8, following admission. Patient blood serum was analysed for their interleukin-6 …
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Urinary Biomarkers and Patient Outcome in Chronic Kidney Disease and Atherosclerotic Heart Disease: The value of IgM-uria and IgG-uria
Risk stratification of patients with chronic kidney disease and atherosclerotic heart disease is crucial. Microalbuminuria (MA) is associated with an increased risk of kidney and cardiovascular (CV) death, especially in patients with diabetes. However, MA in many instances is not sensitive for …
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A Longitudinal Study of Fetal Tissue Transplantation Surgery for the Treatment of Parkinson's Disease: Can Quality of Life and Optimism at Baseline Predict Patient Outcome 10 Years Later?
<p>Parkinson's disease (PD) is a chronic and progressive condition that affects the physical, emotional, and social functioning of individuals. Freed et al. (2001) conducted a double-blind sham-controlled trial to investigate the effectiveness of fetal tissue transplantation for the treatment of …
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Unraveling the genetic determinants of virulence in Cryptococcus neoformans
… pathogen that causes meningitis, primarily in patients who are immunocompromised. It is most common in populations with advanced HIV disease in low- and middle-income countries, especially in sub–Saharan Africa, South America, and southeast Asia. Even with improvements in treatments, the …
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Effect of renal replacement therapy on acute kidney injury in sepsis patients
… of the kidneys and overall ameliorate patients' outcomes. The goal of this work is to determine the relationship between undergoing RRT and patient outcome. The Philips-MIT eICU Collaborative Research Database was used to identify patients with sepsis and acute kidney injury, and split …
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Improving the peri-operative management of patients undergoing free tissue transfer for head and neck malignancy
Abstract The cohort of patients with oral malignancy is typically of advanced age with significant comorbidity. The causative factors for such malignancies, such as tobacco and alcohol, are also those which result in cardiovascular disease. As a result patients undergoing ablative and …
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Clinical Applications of Neuromonitoring Following Acute Brain Injury
… to which cerebral hemodynamics and subsequently, patient outcome, have been impacted following acute brain injury (ABI). This Ph.D. thesis examines both prospective and retrospective patient data in both neurocritical and general intensive care patients. Thirty neurotrauma patients and forty …
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Roles of the ING1 Epigenetic Regulator in Breast Cancer
… was unknown, we analyzed ING1 levels in patient samples and correlated it to patient outcome. We also studied the effects of altering ING1 levels in metastasis assays in vitro and mouse metastasis model in vivo. ING1 levels were lower in tumors compared to adjacent normal breast tissue …
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CRITICALLY ILL PATIENTS WITH COVID-19 PNEUMONIA: PATHOPHYSIOLOGY, IMPACT OF VACCINE, AND CLINICAL OUTCOME.
… on gas exchange in mechanically ventilated patients with ARDS due to COVID-19. Two FiO2 (100% and 40%) were tested at 3 decreasing levels of PEEP (15, 10, and 5 cmH2O). In the fourteen enrolled patients, PEEP of 15 cmH2O, despite resulting in the highest oxygenation, was associated with …
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Using Brain Topological Features Extracted from Resting State fMRI to Classify Autism Spectrum Disorder
… identification of this disorder leads to better patient outcome. Many imaging studies have been conducted in order to gather insight into the inner workings of this disorder with some using machine learning in autism diagnosis. The success of this approach is heavily dependent on the features …
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Prehospital endotracheal intubation practices by paramedics in the provincial ambulance service of the Western Cape province of South Africa
… the incidence of complications and adverse outcomes, and by assessing the impact of the procedure on patient care. This dissertation includes a comprehensive international literature review of studies related to prehospital endotracheal intubation, and discusses and compares these published …
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Remote controlled drug release in drug-eluting stents
… the cardiologist, to maximise drug efficacy and patient outcome.
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A Modern Statistical Approach to Quality Improvement in Health Care using Quantile Regression
… be chosen among many potential process-based and patient outcome measures. Further, when comparing providers, one must take into account the fact that patients are not homogeneous across providers. Accounting for the latter with clinical risk adjustment models is a complicated and controversial …
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Investigating EEG burst suppression for coma outcome prediction
… time Marion [2009]. Predicting whether or not a patient will wake up from coma, as well as the patient's neurological function after waking up, is an important task in guiding treatment decisions for physicians and family of the patient. This project seeks to improve this prediction process by …
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