Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 92 for “"PRS"”.
-
Evolução molecular Darwiniana nas proteínas relacionadas à patogênese (PRs) em plantas
Um total de 201 seqüências de DNA, de 50 espécies pertencentes a 32 gêneros e 12 famílias, foi investigado através do método da máxima verossimilhança para identificar, nas proteínas respectivas, possíveis códons nos quais estivesse ocorrendo seleção positiva. Foram considerados 15 tipos de …
-
Investigation into PRS-precoded, constant-envelope, continuous-phase digital modulation schemes
Partial response signaling ( PRS) has been used successfully to improve the spectral properties of Pulse Amplitude Modulated (PAM) digital transmission systems. This thesis investigation studied the effect of PRS on frequency- and phase-modulated carrier systems, in particular on their spectral …
-
The use of the Personal Response System (PRS) at King Khalid University for learning development
… the use of the Personal Response System (PRS) to increase interactivity in the classroom and change the form of learning from transmissive to constructive learning in Saudi Higher Education. PRS is a technology to enable students in the educational environment to answer questions …
-
Biomarker-And Pathway-Informed Polygenic Risk Scores for Alzheimer's Disease and Related Disorders
… of the overall risk. Polygenic Risk Scores (PRS) are a mathematical construct or composite that aggregates the small effects of multiple variants into a single score. Potential applications of PRS include risk stratification, biomarker discovery and increased prognostic accuracy. A systematic …
-
Dadaab’s Hidden Ties: How Colonial Legacies and Informal Economies Contribute to Protracted Refugee Situations
<p>Protracted Refugee Situations (PRS) persist despite the founding intentions of the international refugee regime. Explanations behind PRS typically focus on international law, human rights, and security concerns, while the conventional media narrative presents an oversimplification that erases …
-
Risk Prediction and Value of Polygenic Risk Scores in Colorectal Cancer Screening
… genetic variants, known as Polygenic risk Score (PRS), have shown promises to guide personalized screening for colorectal cancer (CRC). Continuous efforts to improve PRS risk prediction are needed for clinical use, and understanding its added value of guiding CRC screening is needed to inform …
-
Representation Learning Associates Patients’ Risks for Metabolic Diseases with Features of Their Lipocytes
Polygenic risk scores (PRS) estimate an individual’s risk of developing a certain disease, suggesting that differences between cells of individuals with high versus low PRS could give us insight into the cellular disease mechanisms. To study metabolic diseases, we analyze the distribution of cell …
-
Personalising Predictive Prevention of Cardiovascular Disease using Electronic Health Records and Genomics
… risk factors called polygenic risk scores (PRS). However, little is known as to whether PRS will benefit CVD prioritisation. Therefore, the second aim of this thesis is to investigate the potential benefits of PRS when used for both prioritisation and formal assessments. Third, a future …
-
A Genome-wide Association Study of Schizophrenia in the South African Xhosa and Generalizability of Polygenic Risk Score across African populations
… prediction accuracy of polygenic risk scores (PRS) derived from EUR ancestry populations is less accurate in populations of non-European ancestry, and least accurate in African (AFR) ancestry populations. The extent to which PRS prediction accuracy varies within AFR ancestry populations has …
-
Private Random Variate Sampling for Secure and Federated Polygenic Risk Scores
Polygenic risk scores (PRS) are used to quantify the additive effect of single nucleotide polymorphisms (SNPs) on an individual’s genetic risk for developing a particular trait or condition. Collaborations between data centers are important for improving the statistical power and validity of PRS …
-
Development and Validation of a Novel Partner Rumination Scale
… factor analyses of the Partner Rumination Scale (PRS) yielded a one-factor model that was supported via confirmatory factor analysis, and then cross-validated in an independent sample. The PRS showed excellent internal consistency and test-retest reliability. Evidence of convergent and …
-
Studies on the regulation in vivo and structure/function relationships of the enzyme 5-phosphoribosyl-alpha-1-pyrophosphate synthetase from Salmonella typhimurium
… or the regulation of the structural gene (prs) in vivo. Site directed mutagenesis and characterization of mutant proteins were used to examine possible residues involved in catalysis. Initial studies of the transcriptional regulation of the prs gene were also conducted.
-
Design, manufacturing and testing of parachute recovery system for aludra SR-10 unmanned aerial vehicle (UAV)
… and testing of Parachute Recovery System (PRS) on the Aludra SR-10 UAV. A design work of PRS involving in defining a suitable type of parachute design, parachute compartment, parachute deployment and activation mechanism system. This study was performed by simulation approach (using …
-
An Investigation of Dual-Band Fabry-Pérot Resonant Cavity Antennas
… partially reflective surface, also known as the PRS) and a lower cavity region (between the ground plane and the FSS). The conventional single-cavity Fabry-Pérot antenna is studied first, and the theory is then extended to the proposed dual-band structure. The 2-D arrays of metal patches that …
-
Genetic and epigenetic associations with child development and mental health in a South African birth cohort
… the associations between polygenic risk scores (PRS), epigenetic age (EA) deviation, DNA methylation risk scores (MRS), and key neurodevelopmental disorders such as attention-deficit hyperactivity disorder (ADHD). However, most work has thus far been undertaken in high-income countries (HICs) …
-
Comparisons: BASC-2 Parent and Teacher Reports for Children on the DSM-5 Autism Spectrum
… research has compared the Parent Rating Scale (PRS) and Teacher Rating Scale (TRS) of the BASC-2. The current study examined the PRS and TRS of the BASC-2 for children on the DSM-5 autism spectrum. Utilizing a sample of 67 children and adolescents with ASD, the PRS and TRS of the BASC-2 were …
-
Interacción de síntomas neuropsiquiátricos, Poligenic risk scores y APOE en la conversión del deterioro cognitivo leve a demencia
… de biomarcadores genéticos en forma de PRS supondría un avance en la evaluación del riesgo de la enfermedad de Alzheimer. Se muestran datos propios del proyecto GR@CE con 755 pacientes con deterioro cognitivo leve en los que se evalúa la conversión a demencia mediante datos de GWAS en …
-
Histochemical and biochemical changes in human muscle following 17 days of unilateral lower limb suspension
… System for Children-Parent Rating Scales (BASC-PRS), and a demographic survey. In addition, the biological mothers of 120 children with no characteristics of ADHD or any other behavior disorders completed only the MPS so that exploratory factor analysis of the MPS could be completed.Following …
-
Exploration of the Relationships between and among Role Strain, Faculty Stress, and Organizational Support for Clinical Nurse Faculty Faced with a Decision to Assign a Failing Grade
… the relationships between perceived role strain (PRS), perceived faculty stress (PFS), and perceived organizational support (POS) for CNF who faced the decision to assign a failing grade to a student in a clinical practicum. A national sample of 390 predominantly full-time, female, experienced CNF …
-
Evaluating and enhancing cardiovascular disease risk prediction with algorithmic fairness
… for clinical use - polygenic risk scores (PRS), demonstrating that PRS are not inherently less fair than conventional individual risk factors. The final results chapter introduces a two-stage method to integrate PRS into CVD risk stratification. The impact of PRS integration on both …
Page 1 of 5