Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 157 for “"POLO"”.
-
Studies of Aurora and Polo Kinases During Cell Division in C. elegans
… elegans, we investigated the roles of Aurora and Polo kinases during the release of meiotic chromosome cohesion. We found that the Aurora B kinase AIR-2 is localized to sub-chromosomal regions representing the last points of contact between homologous chromosomes in meiosis I and between sister …
-
Funktionelle Charakterisierung der humanen Polo-Kinase Plk2/Snk im Zell- und Centrosomenzyklus
… sowie die Entstehung von Krebs zu verstehen. Polo-Kinasen sind eine kürzlich beschriebene, neue Proteinfamilie deren Mitglieder an der Regulation des Zellzyklus beteiligt sind. Die bislang am besten untersuchte humane Polo-Kinase ist Plk1, welche wichtige mitotische Prozesse reguliert. Dagegen …
-
The role of Polo-like kinase 2 in synaptic function and plasticity
… activity, the activity-inducible protein kinase, Polo-like kinase 2 (Plk2), was required for synaptic scaling in dissociated culture and for reducing membrane excitability in slice culture-two principal compensatory mechanisms underlying homeostatic plasticity. Inhibition of Plk2 activity in slice …
-
ROLE OF POLO KINASE CDC5 IN DNA DAMAGE PROCESSING AND REPAIR PATHWAY CHOICE.
Le Polo-chinasi (Polo-Like Kinases; PLK) sono regolatori del ciclo cellulare in tutti gli eucarioti e sono state implicate nel mantenimento della stabilità genomica. La scelta ed efficienza dei meccanismi di riparazione del DNA dipendono dalla progressione nel ciclo cellulare, ma i meccanismi …
-
SYNTHETIC DOSAGE LETHAL INTERACTIONS OF POLO-LIKE KINASE 1 AND THEIR APPLICATION IN CANCER THERAPEUTICS
… in the identification of effective targets. Polo-like kinase 1 is overexpressed near ubiquitously across cancer types and dysregulation of polo-like kinase 1 is closely tied to chromosomal instability and tumour heterogeneity. Despite promising pre-clinical studies, clinical trials of …
-
Satisfação dos usuários da biblioteca do polo presencial da UFPB no município de Mari/PB
The research has the purpose to analyze the use and informal needs of the UFPB Virtual Presence Pole Library in Mari/PB District. The theorist referential mentions about the users study, information necessity and universitarian library. The research is of descriptive and exploratory manner and …
-
Perfil mineral del caballo de polo en reposo y post-ejercicio en relación a su alimentación
Fil: Martin, Santiago. Universidad Católica Argentina. Facultad de Ingeniería y Ciencias Agrarias; Argentina
-
Determining Mechanisms of Response to Polo-Like Kinase 1 Inhibition In Non-Small Cell Lung Cancer
… data for a broad range of drugs. We identified polo-like kinase 1 (Plk1) as the most promising target for further investigation based on a subset of sensitive cell lines and inhibitors that were in advanced clinical development. To identify potential biomarkers of response and mechanisms of Plk1 …
-
G2/M checkpoint associated repression of polo-like kinase-1 mediated by the tumour suppressor, p53
Polo-like Kinase-1 (PLK1) is an important mediator of the G2/M phase of the cell cycle that is down-regulated in a DNA damage dependent manner. In cancer cells PLK1 is overexpressed and allows for continued proliferation of the cell by overriding this checkpoint. Here I show that PLK1 is …
-
Estudo do comprometimento do endividamento público e privado por parte dos produtores do Polo Petrolina /Juazeiro.
… identificar o comprometimento dos produtores do Polo Petrolina/Juazeiro em relação às suas dívidas junto ao Setor Público e Privado, bem como as causas dessas inadimplências. A amostra utilizada neste trabalho representa dados em corte transversal para o ano de 2009 referentes a 1337 produtores …
-
The musculoskeletal profile of female adolescent elite water polo players and the factors affecting throwing performance.
Water polo is a popular water-based sport and a physically challenging game. Water polo demands extreme glenohumeral joint ranges of motion while throwing overhead, which is an entire-body movement requiring accuracy and precision. Water polo is unique as it loads the shoulder in four different …
-
The musculoskeletal profile of female adolescent elite water polo players and the factors affecting throwing performance.
Water polo is a popular water-based sport and a physically challenging game. Water polo demands extreme glenohumeral joint ranges of motion while throwing overhead, which is an entire-body movement requiring accuracy and precision. Water polo is unique as it loads the shoulder in four different …
-
Screening for risk factors associated with non-specific shoulder pain in mail adolescent water polo players
Water polo is a fast-growing aquatic sport that combines swimming, overhead throwing, defending and grappling. There are great demands placed on the shoulder to complete these activities and shoulder pain is the most common musculoskeletal complaint among water polo players. The aetiology of …
-
Agroecologia e agência em territórios: o Polo Agroecológico e de Produção Orgânica da Zona da Mata Mineira
… É nesse sentido que, em 2018, é instituído o Polo Agroecológico e de Produção Orgânica da Zona da Mata mineira, como forma de reconhecimento “oficial” do movimento agroecológico da região pelo Estado. Entretanto, passados quase quatro anos da Lei, o Polo ainda parece distante da base. A partir …
-
Análise do Empreendimento Carrefour como polo gerador de tráfego no Bairro Jardim São Paulo – João Pessoa/PB.
Deploying Polos Traffic Generators usually comes to successful impacts in several areas surrounding the project, mainly in road circulation. The increased volume of traffic on the roads surrounding the polo traffic generator, reduces service levels airway, resulting in congestion, increased travel …
-
Polo-Like Kinase 1 and Smooth Muscle Cells in Coronary Artery Bypass Conduits and Coronary Arteries Following Angioplasty
… unknown. In this study, we examined the role of polo-like kinase (PLK)-1 in the PLK1/pPLK1-pCDK1-p-Histone H3 pathway in mediating mitotic progression of smooth muscle cells (SMCs) from human IMA and SV in the development of IH leading to veingraft disease. We also show in vivo data in support of …
-
Identifying risk factors contributing to the development of shoulder pain and injury in male, adolescent water polo players
Water polo is a fast-growing adolescent sport that consists of swimming, defending and overhead shooting in an aquatic environment. The high demands on the shoulder to complete these tasks are proposed to cause the high injury incidence reported in the sport. The novelty of this research rests in …
-
IMPACTO SÓCIO-ECONÔMICO COM A IMPLANTAÇÃO DE UM POLO CANAVIEIRO: UM ESTUDO DE CASO NO MUNICÍPIO DE BAMBUÍ-MG
… Quais as relações existentes entre a presença do polo canavieiro e os indicadores socioeconômicos do município? 3) Houve impactos no ambiente social e econômico com a implantação do polo canavieiro no município de Bambuí, MG? O objetivo desta pesquisa foi o de identificar os impactos sociais e …
-
A biblioteca escolar enquanto polo dinamizador do trabalho colaborativo e do cruzamento de saberes: reflexão crítica de uma prática
O trabalho colaborativo e o cruzamento de saberes apresentam-se como elementos prementes à necessária renovação das práticas pedagógicas atuais e sua adequação aos desafios da sociedade de informação e de um mundo cada vez mais global. Esta renovação surge reforçada pelas mais recentes medidas …
-
Modulation of mitotic progression and cell cycle checkpoints by phosphorylation-dependent protein-protein interactions
… chromosomal aberrations and genomic instability. Polo-like-kinase-1 is a critical mitotic regulator, overexpressed in human tumors, that functions in mitotic entry after cellular stress, centrosome maturation, mitotic spindle control, and cytokinesis, which are all disregulated in cancer cells. To …
Page 1 of 8