Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 24 for “"PIF"”.
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Cellular signalling pathways involved in muscle atrophy in cancer cachexia
… of 24kDa, termed Proteolysis-Inducing Factor (PIF). PIF induced a significant increase in protein degradation, peaking at 4.2nM PIF (p<0.001), ‘chymotrypsin-like’ activity of the proteasome (p<0.001) and increased expression of components of the ATP-ubiquitin dependent proteolytic pathway. This …
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Muscle catabolism in cancer and its attenuation by eicosapentaenic acid
… EPA. Recently a proteolysis inducing factor (PIF) has been isolated from the MAC16 tumour, and from the serum and urine of cachectic cancer patients. Previous studies have shown that PIF induces protein degradation in vitro, and that this is possibly mediated through 15-hydroxyeicosatetraenoic …
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The role of soluble factors affecting the major histocompatibility complex class I molecules In an IN VITRO model of the fetomaternal interface
… Our premise is that PreImplantation Factor (PIF), a 15 amino acid peptide secreted only by viable embryos, seems to plays a key role in this regulation. In this study we have used the JEG-3 cell line as a human trophoblastic model to study the effect of PIF on HLA-I expression. JEG-3 cells …
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Identification of SPINK2 as biomarker of primary chemoresistance in acute myeloid leukemia and its biochemical role in normal bone marrow.
… per questo detti “Primary Induction Failure” (PIF). Questo studio origina dall’individuazione di alterazioni molecolari caratterizzanti la condizione PIF-LAM: utilizzando dati di RNA-seq e microarray, appartenenti a tre differenti coorti di pazienti pediatrici, sono stati individuati geni …
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Investigation into the mechanisms responsible for muscle atrophy in cancer cachexia
… glycoprotein called proteolysis inducing factor (PIF), which induces skeletal muscle atrophy via increased protein degradation and decreased protein synthesis. The objective of this study was to investigate the signalling pathway by which PIF reduces protein synthesis in skeletal muscle and to …
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A unique prototyping concept for missile and aviation weapon systems
… manner. The Prototype Integration Facility (PIF) concept builds off the foundation of the existing base of prototyping experience, but integrates unique business principles to form a creative, powerful concept to assist aviation and missile program managers in their quest to rapidly provide …
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The relation between accounting earnings and stock returns: A study of firms receiving a modified audit report.
… the production, investment, and financing (PIF) activities of these firms. Both of these factors--noise in accounting earnings and uncertainty in PIF activities--are expected to be negatively related to the market's responsiveness to earnings. Therefore, firms receiving modified audit …
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Differences in Load Symmetry of the Lower Extremities in Postpartum Women During Daily Tasks and Childcare Loading Conditions
… the sit-to-stand task for the peak impact force (PIF = 9.08% symmetry) and during the stair descent task for the average loading rate (ALR = 15.43% symmetry). The increase in asymmetry during these tasks may be attributed to increased muscle activation and force production. The second purpose of …
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Faculty Advisement and Helpfulness and the Retention of First-Semester Associate Degree Nursing Students
… factors (EF), professional integration factors (PIF), and faculty advisement and helpfulness restricted or supported course retention and success. Harrison’s Faculty Advisement Evaluation Questionnaire (FAEQ) was utilized to determine which faculty advisor characteristics were present and helpful …
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Signatures of natural selection and local adaptation in Populus trichocarpa and Populus deltoides along latitudinal clines
… selective constraint, with some of them (FT-2, PIF-4, FRIGIDA) showing significantly higher variation than the other genes, hinting at the role of non-coding regulatory regions in local adaption. In some cases, the same genes in both species appeared as outliers, including PIF-6, FRI, FT-2, …
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Analysis of phytochrome signaling pathways in Zea mays
… transduce light signals via interaction with PIFs (phytochrome interacting factors), a sub-family of bHLH proteins. The recent whole genome duplication in maize may have led to divergence in the structure and function of phytochrome mediated signaling pathways. Here, I found that ZmphyB1, one …
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EXTRACT NESSENTIAL FACTORS FROM HIGH DIMENSIONAL BIG DATA
… factors from big data. First, we proposed the PIF and SG-ICA to extract factors from high-dimensional data. Secondly, we proposed 3D Image FPCA to extract factors from 3-dimensional functional MRI data. The proposed methods display superior performance compared to conventional methods.
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PREVENZIONE E REPRESSIONE DELLA CORRUZIONE NELLE FONTI SOVRANAZIONALI: TRA OBBLIGHI E PROSPETTIVE DI RIFORMA
… di diritto europeo derivato — dalla Convenzione PIF alla Direttiva PIF del 2017, fino alla nuova Direttiva anticorruzione approvata il 26 marzo 2026 — sul versante unionale. Un ruolo metodologico centrale è riservato all'analisi della prassi dei meccanismi di monitoraggio — WGB, GRECO, IRM — che …
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Risk factors associated with the exposure of neonates to acinetobacters through the ingestion of infant formula in NICUs
… to the consumption of powdered infant formula (PIF). The ingestion of contaminated infant formula is a particularly unexplored mechanism of acquiring Acinetobacter infections. Therefore, this research work aimed to analyse the potential risk factors associated with the consumption of a …
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Comparison of epididymal and ejaculated sperm collected from the same Holstein bulls
… bull sperm was unaffected by the inclusion of PIF to the culture medium. PIF was also unable to improve or inhibit the in vitro fertility of cryopreserved ejaculated bull sperm. In Experiment V, ejaculated sperm with heparin and epididymal sperm with and without heparin were similar in their …
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Exploration of Movement Variability and Limb Loading Asymmetry During Simulated Daily Functional Tasks
… determined for each task. The peak impact force (PIF) did not show a significant interaction between sex and task (p=0.627) or between sexes (p=0.685). The PIF did show significant between-task differences (p < 0.001), where the highest mean CV was observed in the sit-to-stand task and the lowest …
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Understanding the Impact of ACL Reconstruction on Normalization Methods and Identifying Predictive Factors of Landing Symmetry
… assess performance, including peak impact force (PIF), loading rate, impulse, and time to peak. These results show a need to revisit common assumptions used to analyze data when including patients with ACLR. Future studies could conduct a similar analysis in different clinical populations. …
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Interessi finanziari e diritto sanzionatorio comunitario
… fine si esamina la ricezione della Convenzione PIF nel Codice Penale spagnolo e i principali problemi di cui derivano. L’originalità dell’approccio proposto deriva dell’assenza di un lavoro recente che, in modo esclusivo e concreto, analizzi la protezione amministrativa e penale degli interessi …
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Genomic profiling of the neonatal meningitic Cronobacter sakazakll clonal complex 4
… data suggested powdered infant formula (PIF) to be the dominant, yet not the exclusive source of outbreak for the C. sakazakii isolates. The current PhD study was the first to explore the genomes of C. sakazakii CC4 revealing some interesting variations. Future studies are warranted to …
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