Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 7 of 7 for “"New Approach Methodologies"”.
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Metabolism and mechanistic toxicity of environmental pollutants in fish models : integrating in vitro and in vivo systems for ecotoxicological studies.
… and populations are at risk. However, these approaches are often hindered by cost, ethic, and scientific limitations, making them unable to provide a thorough representation of exposure conditions and resulting adverse effects. Recently, significant research efforts have highlighted the need …
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Towards an understanding of the developmental zebrafish (Danio rerio) proteome and impacts of age-specific sensitivities with a model toxicant.
… Thus, it is necessary for modern toxicology approaches to employ the adverse outcome pathway (AOP) framework and new approach methodologies to increase throughput, reduce cost, and link molecular interactions to organismal and population scale consequences through the use of omic tools and …
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Towards an understanding of synthetic glucocorticoid hazards in aquatic systems.
… agonism. This dissertation integrated diverse new approach methodologies to advance an understanding of the water quality hazards presented by an important class of endocrine disrupting contaminants of emerging concern.
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Analysis of Virtual Control Groups and Inter-species Concordance using Preclinical Toxicity Data
… and subsequent banning of animal testing for new cosmetic products (Yang et al., 2021), and aim to drive the development of New Approach Methodologies (NAMs) for the toxicity testing of drugs (Ball et al., 2022; Fischer et al., 2020; Parish et al., 2020). These issues have motivated two lines …
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L'applicazione delle metodologie del nuovo approccio in vitro per chiarire i meccanismi di potenziale tossicità dell'EVP e delle sigarette combustibili
Il fumo è una causa di gravi malattie nei fumatori tra cui il cancro ai polmoni, la broncopneumopatia cronica ostruttiva (BPCO) e le malattie cardiovascolari. Come riportato dall'OMS nel 2020 “il 22,3% della popolazione mondiale consumava tabacco, il 36,7% di tutti gli uomini e il 7,8% delle donne …