Global ETD Search
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Showing 1 to 2 of 2 for “"Nairovirus"”.
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Biophysical Characterization of the vOTU Proteases from the CCHF and Dugbe Nairoviruses
… tumor domain protease superfamily (vOTU) from nairoviruses, and the structural reasons for their specificities. The vOTU from the Crimean-Congo Hemorrhagic Fever Virus (CCHFV) has been implicated in the down-regulation of the innate immune response through its ability to cleave …
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The production of a Crimean-Congo haemorrhagic fever virus diagnostic antigen in plants
… Hemorrhagic Fever Virus (CCHFV), a nairovirus that forms part of the Bunyaviridae family. CCHFV has a case fatality rate of approximately 40%. Current diagnostic methods for CCHFV involve the use of live virus antigen, requiring biosafety level 4 (BSL4) conditions for safe handling. …