Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 18 of 18 for “"Nacc"”.
-
Intra-nacc adenosine and its role in mediating palatable food intake: interactions with striatal opioids
… The present study investigated the intra-NAcc effects of selective A1 and A2A adenosine receptor ligands alone and when co-administered with the [mu]-opioid agonist DAMGO or the opiate antagonist naltrexone. The influence of the A1 receptor agonist CCPA, the A1 receptor antagonist DPX, the …
-
Role of the Subthalamic Nucleus in the Circuitry Mediating Food- and Cocaine-Seeking Behavior
… circuitry that includes the nucleus accumbens (NAcc), a structure belonging to the mesocorticolimbic circuit which has been identified as the neural substrate of the reinforcing effects of reward. Here, we assess the effects of bilateral STN lesions on the self-administration (SA) and subsequent …
-
Effects of dopamine depletion in the nucleus accumbens on lateral hypothalamic self-stimulation in the rat
… the dopaminergic input to the nucleus accumbens (NAcc). We reexamined the effects of dopamine depletion induced by 6-hydroxydopamine (6-OHDA) on lateral hypothalamic (LH) self-stimulation using within-subject analysis. To minimize motor deficits due to destruction of the dorsal striatal …
-
A Comparison of the Manipulations of Dopaminergic, Opioidergic or Serotonergic Systems within the Nucleus Acccumbens on the Cue-Evoked Relapse to Food-Seeking
… research indicates that the nucleus accumbens (NAcc) is a critical brain region involved in the relapse to drug-seeking behaviors and may likewise be involved in dietary relapse. These three novel experiments utilized a relapse to food-seeking paradigm to test the effects of intra-accumbal …
-
Pituitary adenylate cyclase-activating polypeptide regulates excessive alcohol consumption
… observed selectively in the Nucleus Accumbens (NAcc) Core of alcohol-preferring compared to Wistar rats. Proving the functional relevance of these changes, excessive drinking in alcohol-preferring rats was markedly reduced following microinfusion of the PAC1 antagonist into the Core, but not the …
-
Product design for supply chain : quantifying the costs of complexity in Hewlett-Packard's retail desktop PC business
… Company's North America Consumer Computing (NACC) division has faced pressures to increase retail product variety in response to growing customer demand. As they pursue incremental revenue and market share to meet corporate milestones, their, product portfolio grows and the overall complexity …
-
Experiential Education Approaches in Nonprofit Management and Leadership Education: An Examination of Master's Degree Programs Associated with the Nonprofit Academic Centers Council
… with the Nonprofit Academic Centers Council (NACC), the organization that supposedly includes the country's trend-setting nonprofit programs. This study, therefore, documented (a) the types of experiential education approaches offered in nonprofit-focused master's degree programs associated …
-
Cholinesterase Inhibitors and Neuropathology of Cerebrovascular Disease and Other Dementias in Patients with Alzheimer’s Disease: A Study of NACC Autopsy and Medical History Data, 2005 – 2017
In vitro testing of cholinesterase inhibitors suggested protective effects against neuronal toxicity from multiple sources. Investigations in primates found ChEI restored cerebral blood flow. Work in animals suggests ChEI may have a neuroprotective effect, though not necessarily impacting …
-
The role of estradiol in astrocyte and neuron communication
… (ER) expression in the nucleus accumbens core (NAcC) and CA1 of the hippocampus (Hipp) of adult female and male mice. I then used calcium imaging techniques in hippocampal slices to monitor astrocyte calcium activity in situ and to test whether astrocytes responded to the estrogen 17β-estradiol …
-
Evaluation of Glutamatergic Treatment in Reducing Nicotine Seeking Behavior in Rats
… cortex (PFC) to the nucleus accumbens (Nacc) as vital in the reinstatement of drug-seeking behavior. Restoring basal concentrations of extracellular GLU, thereby increasing tonic activation of the presynaptic group II metabotropic GLU receptors (mGluR2/3) by a single injection of N- …
-
Full-Gestational Exposure to Nicotine and Ethanol Results in Long-Term Dysregulation in the Ventral Tegmental Area
… neurons that project to the nucleus accumbens (NAcc).</p> <p>Our animal model of full gestational exposure to Nic+EtOH exposes the developing brain to both drugs throughout the entire 3 trimester human equivalent [i.e. gestational days (GD) 1-22 and postnatal days (PN) 2-12]. Using …
-
Novel insights into the role of the GABAB receptor in depression and anxiety
… in the hippocampus and in the nucleus accumbens (NAcc), a critical area for anhedonia thus suggesting that enhanced stress-induced neuronal activation in the hippocampus and NAcc in GABAB(1b)-/- mice may be important for their antidepressant-like phenotype and their resilience to stress-induced …
-
Investigation and design of a secure, transportable fluoride-salt-cooled high-temperature reactor (TFHR) for isolated locations
… TFHR uses a nuclear air Brayton combined cycle (NACC) for electricity generation, adapted from an off the shelf GE aero-derivative gas turbine. The NACC incorporates a combustible fuel injection port between the high and low pressure turbines which can be used to raise the temperature of the …
-
Contribuições da pedagogia na casa da criança com câncer da Paraíba: de mãos dadas pela vida
… de Apoio a Crianças com Câncer da Paraíba (NACC), known as Casa da Criança com Câncer; linked to a Project from the PROLICEN / UFPB, under the coordination of Professor Ana Maria Coutinho Bernardo, during 2013, 2014 and 2015. This study aimed the development of educational practices from the …
-
CHARACTERIZATION OF TRANSMEMBRANE PROTEIN 35 EXPRESSION: CONSIDERATIONS OF SEX AND OVARIAN HORMONES
… preoptic nucleus (MPN), nucleus accumbens core (NAcc), nucleus accumbens shell (NAcsh), suprachiasmatic nucleus (SCN), and ventromedial hypothalamus (VMH). Of these brain areas, ovarian hormones induced TMEM35 expression in the AH, CA1 of the hippocampal formation, MAd, MCU, NAcsh, PVN, and VMHm. …
-
Effects of Δ9-Tetrahydrocannabinol on Neural Reward Anticipation Among Young Adult Cannabis Users
… of interest (ROIs): the nucleus accumbens (NAcc), caudate, and putamen. Multiple linear regressions examined the relationship between problematic cannabis use and reward anticipation under the PBO condition (Aim 1). Repeated-measures analyses of covariance (RM-ANCOVAs) tested main and …
-
Modelling the pathophysiology of schizophrenia and methamphetamine-induced psychosis: A structural magnetic resonance imaging and cytokine study
… right caudate and bilateral putamen and NAcc (nucleus accumbens) volumes were reported in SCZ compared to MAP and CON , with increased right pallidus volumes in SCZ compared to MAP, 3) decreased frontal cortical thickness was reported in SCZ and MAP compared to CON, 4) decreased frontal …
-
Interazione dopamina-ossitocina nel controllo centrale della risposta erettile
We investigated: 1) the effect of a pro-erectile dose of apomorphine, a mixed dopamine receptor agonist, injected into the PVN on the release of dopamine by mesolimbic dopaminergic neurons in the “shell” of the nucleus accumbens; 2) the effect of oxytocin injected into the VTA on penile erection …