Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"NGAL"”.
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Neutrophil gelatinase-associated lipocalin (NGAL) and matrix metalloproteinases (MMPs) as biomarkers of bladder cancer development and progression
Neutrophil gelatinase-associated lipocalin (NGAL), also called lipocalin-2, is a secreted protein belonging to the lipocalin family proteins and actively participates into the proliferation, differentiation, and development of human tissues, including tumours. It positively modulates the activity …
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Migration Stimulating Factor, the search for inhibitors.
… as Neutrophil Gelatinase Associated Lipocalin (NGAL). Both recombinant and cell-produced NGAL neutralise the motogenic activity of MSF. This novel bioactivity for NGAL is not dependent on its iron transportation capability or direct binding to MSF. HaCaT cells also secrete MSF; the bioactivity …
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Predictive Role of NGAL – Neutrophil Gelatinase-Associated Lipocalin as an Early Marker for Renal Injury in Patients with Diabetes Mellitus Type 1 And Type 2 // Предиктивна роля на NGAL – неутрофил гелатиназа асоцииран липокалин като ранен маркер за бъбречно увреждане при пациенти със ЗД тип 1 и ЗД тип 2
… на Неутрофил гелатиназа-асоцииран липокалин (NGAL) като маркер за бъбречно увреждане при пациенти със захарен диабет (ЗД). Съществен принос са определените възрастово и полово диференцирани референтни граници на pNGAL, uNGAL и uNGAL/uCreatinine (UNC) за българската популация, измерени чрез …
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DIAGNOSI PRECOCE DEL DANNO DA ISCHEMIA RIPERFUSIONE E DELLA DISFUNZIONE RENALE POSTTRAPIANTO: RUOLO DELLA LIPOCALINA ASSOCIATA ALLA GELATINASI NEUTROFILA (NGAL)
… è stato quello di verificare: - l'utilità di NGAL come marcatore precoce e indice predittivo di DGF nell'immediato post trapianto e se l'andamento di NGAL nella prima settimana dopo trapianto renale presenta specifiche correlazioni con l'andamento del suddetto organo. - l'utilità dell HO-1 …
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An investigation of a neuro-inflammatory profile of HIV-associated neurocognitive disorders
… and neutrophil gelatinase-associated lipocalin (NGAL) levels were significantly higher, while matrix metalloproteinase (MMP)9 levels were significantly lower in PLWH. The results further showed that in PLWH, worse psychomotor processing speed was associated with higher TYMP and NGAL levels and …
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Testing the Anti-Inflammatory Effects of Dietary Phytochemicals in Intestinal Inflammation Models
… of neutrophil gelatinase associated lipocalin (NGAL), an antibacterial protein positively correlated with UC severity. Accordingly, we hypothesized that CA would upregulate the NRF2 and decrease inflammation in intestinal inflammation models. We used UC patient-derived colonoids and HT-29 colon …
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Ruolo della metilazione del DNA nella regolazione di SLC22A17 nel melanoma cutaneo
… tra cui la gelatinasi associata alla lipocalina (NGAL) e il suo recettore Solute Carrier Family 22 Member 17 (SLC22A17), entrambi coinvolti nell'omeostasi del ferro mediandone l'afflusso o l'efflusso attraverso la membrana cellulare. Su queste basi, il presente studio ha voluto indagare il ruolo …
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An analysis of the mechanisms of acute kidney injury and novel biomarkers
… and neutrophil gelatinase associated lipocalin (NGAL). This study will investigate how the properties of these new biomarkers are superior when compared to those of serum creatinine in early detection of AKI and specification as to the local site of injury within the nephron. The conclusion is …
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The expression and role of Migration Stimulating Factor (MSF) in oral tumours
… Neutrophil Gelatinase-Asscciated Lipocalin (NGAL). NGAL was shown to bind to and inhibit MSF+aa, but not MSF-aa. The bioactivity of MSF+aa and MSF-aa was inhibited by Insulin-like Growth Factor Binding Protein-7 (IGFBP7), MSF-function-neutralising antibody and antibody to the integrin avß3. …
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Obesity in Patients with Inflammatory Bowel Disease // Затлъстяване при пациенти с хронични възпалителни болести на червата
… circulating levels of human Lipocalin-2/NGAL have been successfully linked as a tool to monitor activity and response to treatment in patients with immune-mediated diseases. The absence of data combining the results of these new noninvasive markers in the study of patients with ulcerative …
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Establishing a Murine Model of Malaria-Associated Acute Kidney Injury and Demonstrating the Contribution of Extrinsic Apoptosis to Tubular Necrosis
… and neutrophil gelatinase-associated lipocalin (NGAL) in serum or urine. These mice exhibited signs of early-stage AKI and sustained tubular damage, which is consistent with what has been reported in MAKI patients. The activation of multiple cell death pathways was evaluated to determine the mode …
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The association of maternal HIV status during pregnancy on longitudinal neuro-immune regulation, and neurodevelopment in HIV-exposed uninfected children
… neutrophil gelatinase-associated lipocalin (NGAL/Lcn2) and metalloproteinase-9 (MMP-9)) were analyzed in all study participants with a multiplex bead array and ELISA. The Bayley Scales of Infant and Toddler Development (Bayley-III) were used to assess the neurodevelopmental domains: …
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HOT study: the development, management and results from phase IIB, randomised controlled trial of heme arginate in recipients of deceased donor renal transplants
… for analysis of urinary biomarkers (KIM-1 and NGAL), taking renal graft biopsies pre-op and day 5 for renal HO-1 analysis and collecting renal function data. DGF was calculated daily. To ensure that all adverse event data was captured, the recipients were closely reviewed for 7 days and their …