Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"NETosis"”.
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Analysis of the Role of Circulating Platelet-Neutrophil Complexes as Regulators of Tumour-Induced Netosis in Indolent and Aggressive Non-Hodgkin’s Lymphomas // Анализ на ролята на циркулиращите неутрофилно-тромбоцитни комплекси като регулатори на тумор-индуцираната нетоза при индолентни и агресивни Нехочкинови лимфоми
… Те активно участват в генерирането на т. нар. NETosis, клетъчна програма за формиране на неутрофилни екстрацелуларни мрежи (NETs). Злокачествените заболявания са рискови фактори за възникването на различни видове тромбоза, което най-често се свързва с процесите на хиперкоагулация, както и със …
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Host-Defense Function of Anuclear Polymorphonuclear Neutrophil in Lung Injury
… Extracellular Traps (NETs). After NET release (NETosis), the PMN generates anuclear cells (PMNcyto). We found that 50% of PMN in lung microvessels had transitioned to PMN cytoplasts (PMNcyto) within 24h exposure to endotoxemia. Despite being anuclear, PMNcyto displayed characteristics distinct …
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Elucidating Mechanisms Involved In Host Microbial-Tumor Interactions
… called Neutrophil Extracellular Trap formation (NETosis) that spatially excluded cytotoxic CD8 T cells. Blockade of IL-17/IL-17RA signaling, neutrophils or NETosis synergized with immunotherapy to reduce advanced PDAC tumor growth.</p> <p>Overall, in this dissertation, we provide novel insights …
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Neutrophil biomechanical properties and immune function in health and inflammatory disease
… levels of type 1 interferons, undergo increased NETosis, and accordingly drive inflammation. Meanwhile, advances in mechanical phenotyping at the University of Cambridge have driven hypotheses of neutrophil trafficking and immune function being intimately linked to cellular biomechanical …
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Novel innate immune functions of saliva
… to undergo a rapid mode of cell death called NETosis, wherein the neutrophils extrude a web to catch microbes in the form of a DNA framework decorated with AMPs known as neutrophil extracellular traps (NETs). These saliva-induced NETs had great capacity for entrapment and killing of bacteria. …
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Neutrophil interactions with Leishmania amastigotes: implications for chronic leishmaniasis
Leishmaniasis is a neglected tropical disease responsible for considerable morbidity and mortality in the developing world. The immune response against Leishmania parasites must be fine-tuned to promote pathogen clearance without triggering excess inflammation, and this requires the concerted …
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Relación entre NETs, microbiota intestinal y translocación bacteriana en pacientes infectados por VIH y en un modelo animal con depleción de BATF
… de trampas extracelulares de neutrófilos (NETs, NETosis), ha sido escasamente estudiada. Como consecuencia de la activación inmune e inflamatoria persistente, las PLWH tienen mayor riesgo de desarrollar enfermedades cardiovasculares. Entre los factores clave que contribuyen a este estado de …
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Investigating Pulmonary Immune Responses that Detect and Counteract Gram-negative Bacterial Infections
Infections of the lungs can cause tremendous tissue damage which often leads to pathogens spreading into the bloodstream. In the airways, Gram-negative bacteria produce biofilms through exopolysaccharide (EPS) that provides microbial protection; however, the impact of EPS on detection remains …