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Showing 1 to 20 of 48 for “"Muscle Protein Synthesis"”.
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Human obesity and its influence on muscle protein synthesis
Improving skeletal muscle health is an important component of obesity treatment. Apart from locomotion, skeletal muscle tissue is fundamental for the regulation of macronutrient metabolism during the postprandial period, which is precisely where metabolic derangements are most often observed. In …
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Impacts of microRNAs on Skeletal Muscle Protein Synthesis and Mitochondrial Quality
… -133, and -206 are under the control of skeletal muscle promoters and affect muscle plasticity and metabolic health. A detailed review on the generation and processing of miRNAs with a view to skeletal muscle brings up intriguing connections in the transcriptional connections between multiple …
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Effect of vasodilation on the response of muscle protein synthesis to insulin in aging
The loss of muscle with aging (sarcopenia) is an important contributor to disability and physical dependence in older people. Studies have recently found that aging is associated with a relative resistance of muscle proteins to the anabolic action of insulin, even in subjects who do not have …
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In Vitro and In Vivo Effects of Leucine on Skeletal Muscle Protein Synthesis and Degradation
The regulatory role of leucine in skeletal muscle protein synthesis and degradation was examined using in vitro and in vivo experimental methods. Two skeletal muscles from young Sprague-Dawley rats were used in all experiments. These muscles were the soleus, a slow-twitch, oxidative muscle and the …
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Dairy milk matrix modulation of inflammation and muscle protein synthesis in adults with excess adiposity
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2025-10-20 without embargo terms
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Leucine is a critical factor determining protein quantity and quality of a complete meal to initiate muscle protein synthesis
Item reinstated by Sarah Shreeves (sshreeve@illinois.edu) on 2012-05-15T10:00:21Z Item was in collections: University of Illinois Dissertations and Theses (ID: 204) Dissertations and Theses - Nutritional Sciences (ID: 680) No. of bitstreams: 4 Norton_Layne.pdf: 2079961 bytes, checksum: …
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Use of a dual isotope method to measure the interaction of branched chain amino acids and insulin in the stimulation of skeletal muscle protein synthesis
… affect the regulation of in vivo skeletal muscle protein synthesis is controversial. To determine their roles in protein synthesis, a dual isotope method using $\sp{14}$C dansyl chloride was adapted for use with radioactive tyrosine. The primary difficulty in adapting the method was …
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Mechanisms of Blood Flow Restriction Exercise in Skeletal Muscle Adaptations
The maintenance of skeletal muscle mass is crucial for human health and long term survival. However, the aging process is associated with an involuntary loss of muscle mass and the inability to maximally stimulate muscle growth ultimately leading to sarcopenia. Extensive research has been conducted …
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Meal timing and composition alter plasma amino acid and skeletal muscle protein metabolism after exercise
… acid responses, fractional rates of skeletal muscle protein synthesis (Ks), or both.
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Regulation of postprandial protein metabolism after food ingestion and exercise
Whole body and skeletal muscle mass is regulated by counterbalanced fluctuations between protein synthesis and breakdown rates. Protein ingestion has been shown to stimulate protein synthesis rates and thus is an important variable within the net protein balance equation dictating a positive …
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Skeletal Muscle Protein Metabolism and Molecular Responses to Endurance Exercise and Nutritional Interventions
It has been suggested that the gradual loss of muscle mass observed with healthy aging is the result of a resistance of aged muscle tissue to normally potent anabolic stimuli. Recent evidence indicates an age-related anabolic resistance in skeletal muscle tissue to exogenous amino acids and to a …
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The Effect of Cancer Cachexia Progression on the Feeding Regulation of Skeletal Muscle Protein Turnover
… is defined as the unintentional loss of skeletal muscle mass with or without fat loss that cannot be reversed by conventional nutritional support. Cachexia occurs in ~20% of cancer patients. More specifically, 50% of lung cancer patients, the most common cancer worldwide, develop cachexia. …
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Protein feeding and exercise recovery
The importance of protein feeding for maximising the anabolic effect of resistance exercise is well established. Ingestion of amino acids or intact protein sources with and without carbohydrate during exercise recovery further stimulates muscle protein synthesis. Less clear is the impact of an …
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Skeletal muscle mass, function, and metabolic regulation between menopause stages in moderately active mid-life females
… the effect of menopause stage on skeletal muscle mass, strength and function and to evaluate the response to resistance exercise training between pre-, peri and post-menopausal mid-life females. Seventy one moderately active pre-, peri, and post-menopausal females were characterised …
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Skeletal Muscle Protein Turnover During Cancer Cachexia In the Apc<sup>min/+</sup> Mouse
… condition associated with the loss of skeletal muscle and fat mass. Muscle wasting exhibits an imbalance in the rate at which proteins are synthesized and degraded, referred to as protein turnover. Our laboratory has shown the ApcMin/+ mouse, a model of colorectal cancer is an excellent model to …
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Effects of Leucine on Skeletal Muscle During 14 d Bed Rest in Middle-aged Adults
… is associated with a slow, progressive loss of muscle mass and strength. Mechanical unloading, such as that commonly experienced during hospitalization or spaceflight, results in a rapid loss of muscle mass and strength, particularly in older adults. Exercise, a potent countermeasure to such …
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Differential BCAA Metabolism in Tissues of Tumor-Bearing Mice: A Path to Understanding Cancer Cachexia
Cancer cachexia is a complex syndrome marked by muscle and fat loss, often resistant to nutritional support. While branched-chain amino acids (BCAAs) stimulate muscle protein synthesis, BCAA-targeted therapies have shown inconsistent results. In this study, a C26 colon cancer mouse model was used …
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The effect of whey protein on insulin and glucose responses in recreationally active males
… and glycemic responses of hydrolyzed whey protein concentrate (WPH) in comparison to its intact form, whey protein concentrate (WPC), and carbohydrate control (CHO) in recreationally active young men over a 3-hr postprandial period. Thirteen subjects aged 23±2.3y (mean±SEM) participated in …
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Chronic Dietary Supplementation of Branched-Chain Amino Acids Does Not Attenuate Muscle Torque Loss in a Mouse Model of Duchenne Muscular Dystrophy
… (DMD) is an X-linked recessive, progressive muscle-wasting disease characterized by mutations in the dystrophin gene. Duchenne muscular dystrophy is the most common and most severe form of inherited muscle diseases, with an incidence of 1 in 3,500 male births1,2. Mutations in the dystrophin …
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Influence of protein nutrition and exercise on muscle metabolism
… there is no clear consensus as to whether protein feeding harnesses any ergogenic benefit for endurance athletes. In this thesis demonstrate no effect of protein on endurance performance. Furthermore, data presented herein indicates that protein co-ingestion does not enhance recovery 24 …
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