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Showing 1 to 5 of 5 for “"Mithramycin"”.

  1. Targeted Inhibition of Sp1 Transcription Factor and Anti-Angiogenesis of Human Pancreatic Cancer

    … angiogenic genes expression were suppressed by mithramycin treatment both in vitro and in vivo. Moreover, mithramycin treatment reduced MVD in vivo. This was consistent with the down-regulation of VEGF, PDGF, and EGFR. Human xenograft pancreatic tumor growth was suppressed by Bevacizumab …

    uthsc Repository record for Targeted Inhibition of Sp1 Transcription Factor and Anti-Angiogenesis of Human Pancreatic Cancer (opens in a new tab)

  2. Regulation der konstitutiven VEGF-Sekretion in der Retinalen Pigmentepithel/Choroidea-Organkultur

    … von HIF-1 - Stattic zur Hemmung von STAT3 - Mithramycin zur Hemmung von Sp1 - ein (biochemischer) NF-κB-Inhibitor - SB203580 zur Hemmung von p38 (MAPK) - SU1498 zur Hemmung einer rezeptorgebundenen Tyrosinkinase am VEGFR2 Getestet wurde innerhalb einer Organkultur mit präpariertem porcinem …

    cau-kiel Repository record for Regulation der konstitutiven VEGF-Sekretion in der Retinalen Pigmentepithel/Choroidea-Organkultur (opens in a new tab)

  3. Investigating novel treatment approaches to combat Clostridioides difficile

    … scaffolds identified were those of mitomycin C, mithramycin A, aureomycin, NP-003875, NAT13-338148, NAT18-355531, and NAT18-355768. Of these, mithramycin A, aureomycin, and NP-003875 were also found to harbor anti-virulence properties as they inhibited toxin production by the pathogen. …

    vt Repository record for Investigating novel treatment approaches to combat Clostridioides difficile (opens in a new tab)