Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"Microstimulation"”.
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Multiple spatial memories in the brain : decoding and modification using microstimulation
Sequential processing --- using multiple sensory stimuli to plan and control a set of ordered movements --- is a central aspect of human behavior. Because previous and future movements must be stored during the execution of any movement in a sequence, memory is an indispensable aspect of sequential …
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Combined fMRI and electrical microstimulation to determine functional connections in visual areas of the primate brain
… combining it with simultaneous, intra cortical microstimulation (EM), and to use these new methods to measure how local, artificially-increased FEF output could modulate visually-driven fMRI activity in earlier cortical regions. The first outcome of this thesis was a novel form of functional …
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Using electrical stimulation for sensory restoration and modulation of attention
… In addition, sub-perceptual electrical microstimulation can be used to modulate top-down behavioral and attentional processes. This thesis explores both applications of electrical stimulation, with the vision that future prosthetic technologies could potentially integrate sense …
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Functional analysis of middle temporal visual area and its associated behavior
… In my thesis research, I applied behavioral and microstimulation techniques to demonstrate the causal connections between neural activity and behavior. Understanding these relationships is one of the fundamental issues needed to be addressed in Neurobiology. Specifically, I focused on the …
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Neuromuscular modularity and behavioral correlates of motor control
… motor commands. In other motor cortical microstimulation experiments, I confirmed that long-train microstimulation is able to evoke complex, convergent movements. Even during highly-trained reaching movements, I found that there was relatively little invariance of the muscular patterns in …
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Skilled Behaviour and Bilateral Motor Map Expression
… kindling model and short-duration intracortical microstimulation (SD-ICMS). Forelimb motor map movements changed considerably from contralateral in sham-kindled rats to ipsilateral and bilateral in rats kindled for over 5 sessions. Furthermore, bilateral movement representations were related to …
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The Impact of Synchrony On Neuronal Coding and Behavior
… we mechanistically tested by performing local microstimulation to induce synchrony in V4 of awake animals. Local microstimulation in V4 replicated the changes in neuronal coding and behavioral performance observed after sleep. We uncovered how synchrony in sleep influences neuronal coding …
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A High-Precision Bioelectric Neural Interface Toward Human-Machine Symbiosis
… signals and delivering high-precision electrical microstimulation. The Neuronix chips are incorporated to create miniaturized neuromodulation devices, including the Scorpius system, to enable bidirectional communications with neural circuits. Results. In a clinical study with human amputees, the …
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Face Motor Cortex Neuroplasticity Associated with Alterations in the Oral Environment of the Adult Rat
… face-M1. This project applied intracortical microstimulation (ICMS) and recordings of evoked muscle electromyographic (EMG) activity to test if changes occur in the ICMS-defined motor representations of tongue-protrusion (genioglossus, GG) and jaw-opening (anterior-digastric, AD) muscles …
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Neural Mapping of Pain and Addiction: Visualizing Dopaminergic Modulation in the Mesocorticolimbic System
… new treatments for addiction. We apply our novel microstimulation experimental system in rat pups perinatally exposed to nicotine. By using our self-fabricated photo-stimulation (PS) device, we can stimulate the VTA and collect dialysate, which is then used to estimate DA released into the NAc. To …
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ELECTROPHYSIOLOGICAL ANALYSIS OF THE RECURRENT RENSHAW CIRCUIT
… microelectrode in the muscle nerve or by microstimulation of the muscle supplied by the axon. The resultant average revealed the motoneuron's response to each single antidromic impulse; a recurrent inhibitory postsynaptic potential, recorded for the first-ever time in this project and …
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Influence of Mouse Motor Cortex on Vocal Musculature
… have over their USVs. We performed intracortical microstimulation (ICMS) with paired electromyographic (EMG) recordings to test whether the direct projection previously identified in mice can generate laryngeal muscle contractions. Simultaneously, we recorded EMG signals from the anterior …
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In vitro feasibility testing of floating light-activated minroelectrical stimulators
One of the major challenges of neural stimulation is the mechanical stress and resulting trauma induced on the implanted electrodes by the constant movement of the interconnects. A potential way of eliminating interconnects is to use floating micro-stimulators that can be activated through optical …