Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 84 for “"Memory cells"”.
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Design methodology for electron-trap memory cells
… for SET based Electron-Trap which is a basic memory cell that has been recently fabricated. Given a circuit topology and the corresponding targeted behaviour, the proposed methodology assists the circuit designer in deriving the circuit parameters in an analytical way. The methodology is based …
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INTRA-TUMORAL INFILTRATION OF GZMKHIGH CD8+ T EFFECTOR MEMORY CELLS IS ASSOCIATED WITH POOR CLINICAL OUTCOME IN NON-METASTATIC COLORECTAL CANCER.
… interplay between neutrophils and CD8+ T cells that impacts on tumor immune escape and relapse. Specifically, we showed that tumor infiltrating neutrophils expressing high levels of CD15 interact with CD8+ T effector memory cells skewing them to produce GZMK, associated with tumor …
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Towards unravelling the immunomodulatory mechanisms of S. mansoni & L. major parasites in a mouse model using transgenesis
… that an understanding of the ability of memory T cells to withstand pathogen manipulation is crucial for the development of effective vaccine strategies to control these pathogens. Therefore, in this study, OVA transgenic S. mansoni and OVA transgenic L. major were generated to use as a …
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Fault-Tolerant Distributed Algorithms for Agreement and Election
… part, we characterize completely the shared-memory requirements for achieving agreement in an asynchronous system of fail-stop processes that die undetectably. There is no agreement protocol that uses only read and write operations, even if at most one process dies. This result implies the …
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Mathematical models of immune responses following vaccination with application to Brucella infection
… of antagonistic pro and anti-inflammatory and memory cells. We show that different characteristics of pro-inflammatory cell development and activity have an impact on the number of memory cells obtained after vaccination.
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Cell-based array for deep sub-micron technologies
… that allows for dense computation blocks, small memory cells, and strong signal drivers. This involves simulating different circuit types with HSPICE to determine ideal transistor sizes. Using Magic and the results of the HSPICE simulations, I explore transistor topologies with different ratios …
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Modulation of CD8+ T Cell Function by Beta2-Adrenergic Receptor Signaling
… has demonstrated that various subsets of CD8+ T cells have differential expression of the ADRB2 transcript. The role of ADRB2 signaling on the differentiation and acute effector functions of CD8+ T cells remains poorly understood. More importantly, its effect on CD8+ T cell memory development …
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Fragments, as I Remember
… installation combining the following three memory cells: photographic images of dioramas derived from my memories; a film projection; and a sculpture composed of butterflies and a visual diary. The accompanying thesis support paper is written as both a journal of my creative thought process …
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Automated and Handcrafted Neural Network Design for Vision Applications
… such as a holistic LSTM with extra designed memory cells and gated operations for pedestrian trajectory prediction and a hybrid transformer-convolutional network for video deraining. To facilitate the applications of designed neural networks, the thesis further presents a semi-supervised …
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In vitro generation and programming of human CD8+ memory T cells
… the generation of persistent and functional memory CD8+ T cells. The integration of a multitude of signals during naïve cell activation plays an important role in the programming of CD8+ T cells responses. However, knowledge of the regulation of naïve cell programming in humans is limited. …
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Screening for genes involved in CD8⁺ T cell cytotoxicity and characterisation of a super-killer
Cytotoxic T Lymphocytes (CTL) are cells of the adaptive immune system that are responsible for the elimination of virally infected, tumorigenic or damaged cells through mechanisms that induce target cell lysis. The aim of this project was to identify genes that can impact CTL lytic capacity, using …
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CHARACTERIZATION OF SNEAK PATH CURRENT EFFECT IN A PEDOT: PSS-BASED ReRAM CROSSBAR ARRAY
… characterization of resistive switching memory crossbar devices fabricated on glass substrates with a structure of Cu/PEDOT: PSS/Ag, with a particular focus on understanding the impact of sneak-path currents on the switching performances. Resistive memory cells, particularly in crossbar …
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Development of a novel co-vaccination approach for pneumococcal and influenza infections
… vaccine efficacy was shown to be reliant on B cells and IL-17 responses. Importantly, immunisation promoted IL-17 production by γδ T cells, as opposed to conventional Th17 cells commonly reported with other pneumococcal whole cell vaccines. Moreover, this study also illustrated that the …
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Flash Memory For Ubiquitous Hardware Security Functions
We demonstrate that unmodified commercial Flash memory can provide three important security functions: true random number generation, digital fingerprinting and information hiding. Use of random telegraph noise (a type of quantum noise source in highly scaled Flash memory cells) enables high …
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Defining mRNA-generated T cell memory in respiratory viral infection
T cell immune memory provides protective effector mechanisms to restrict pathogen growth upon secondary infection, although the ability of T cells generated by novel mRNA-LNP vaccines to restrict viral infection in currently unknown. To address this, we studied antigen specific T cell memory …
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MODULATION OF THE B-CELL REPERTOIRE IN RHEUMATOID ARTHRITIS BY TRANSIENT B-CELL DEPLETION
Although the role of B-cells in autoimmunity is not completely understood, their importance in the pathogenesis of autoimmune diseases has been more appreciated in the past few years. It is now well known that they have roles in addition to (auto) antibody production and are involved by different …
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Macroscopic quantum tunneling in superconducting nanowire devices
… applicability as nanometer-scale superconducting memory cells. We develop precise algorithms allowing us to write and read the information onto such memory cells. We also observe signatures of macroscopic quantum tunneling in these doubly connected devices by observing a saturation in the standard …
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Coordinated Blockade of TGF-β and PD-L1 Promotes Anti-Tumor Immunity in Ovarian Cancer Models
… anti-tumor immune skewing of macrophages, NK cells, and T effector memory cells, corresponding with long-term immunological memory responses. BA treatments enhanced cytotoxicity that was traced back to resident memory T cells and decreased suppressive Gata6+ large peritoneal macrophages in the …
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Commercialization of germanium based nanocrystal memory
… high-density, low-power non-volatile electronic memory devices. Flash memory cells designed for ten years of data retention require the use of a thick tunneling oxide. This compromises writing and reading speed as well as endurance. A smaller device size can be achieved and speed and can be …
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Locally decodable source coding
… many issues such as computational complexity, memory capacity, and memory access requirements must be considered. In conventional source coding, in order to retrieve one coordinate of the source sequence, accessing all the encoded coordinates are required. In other words, querying all of the …
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