Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 18 of 18 for “"Magnetization Transfer"”.
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Accelerated Quantitative Magnetization Transfer (qMT) Imaging
Quantitative magnetization transfer (qMT) is an advanced magnetic resonance imaging (MRI) technique with enhanced specificity to myelin. The acquisition of many images with unique magnetization transfer (MT) saturation results in a signal response curve known as the z-spectrum. The two-pool tissue …
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Diffusion and Magnetization Transfer Studies of Neural Tissue
Our experiments showed that diffusion and magnetization transfer do not offer a unique window to neural function, as had been suggested by some reports in the literature. Rather, our studies taken together with the literature suggest that both these phenomena affect the standard …
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Quantitative magnetization transfer imaging in ultra-high magnetic field (11.7 T).
Quantitative magnetization transfer imaging in ultra-high magnetic field (11.7 T).
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Magnetization Transfer and Diffusion Tensor Imaging in Dogs with Intervertebral Disc Herniation
… surrogates of myelin and axonal integrity using magnetization transfer and diffusion tensor imaging may provide beneficial prognostic details on long-term post-surgical recovery in dogs with spinal cord injury (SCI) secondary to intervertebral disc herniation (IVDH). Hypothesis: Magnetization …
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The dependence of NMR measured diffusion, magnetization transfer, and T2 relaxation on fractional water content in bovine articular cartilage
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1995.
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Validation of magnetic resonance imaging (MRI) as a tool to detect inflammation in the brain
… diffusion-weighted imaging (DWI), quantitative magnetization transfer (QMT), and magnetic resonance spectroscopic imaging (MRSI). EEGs were recorded at resting-state and during performance of an attention task. Vaccine administration induced an increase in fatigue and pro-inflammatory marker …
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Magnetic Resonance imaging of tumour biomarkers in ovarian cancer
… Diffusion kurtosis imaging (DKI), sodium MRI, magnetization transfer (MT) imaging, hyperpolarized carbon-13 MRI and magnetic resonance fingerprinting (MRF) were employed to image ovarian tumours in human subjects. The results of the imaging were compared to semi-quantitative measurements of …
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Non-Invasive Detection of Anaerobic Metabolism in Exercising Muscle Using Proton MRI
… intracellular pH (pHI), and/or changes in magnetization transfer (MT) or other longitudinal relaxation mechanisms. Isolated frog gastrocnemii were treated with iodoacetate (IAA; to inhibit lactate production), NaCN (to maximize lactate production), or left untreated and then performed 60 …
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Mechanistic studies on palladium-catalyzed carbon-nitrogen bond forming reactions
… high degree of insolubility of Pd(Xantphos)₂. Magnetization transfer experiments were used to probe the rate of dissociation of ligand for the bis-ligated species, and reaction calorimetry experiments were performed using the more soluble t-butylXantphos in comparison to Xantphos to determine …
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Development and Application of 19F NMR of Proteins
… experiments based on INEPT and COSY magnetization transfer schemes to correlate the fluorine nucleus to sidechain and backbone 1H, 13C, and 15N atoms, providing complete spectral assignment. The assignment of 3-fluorophenylalanine resonances was achieved using 19F-, and 15N-edited …
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Hyperpolarized Xenon-129 Magnetic Resonance Imaging of Functional Lung Microstructure
… HXe imaging method, multiple exchange time xenon magnetization transfer contrast (MXTC) is implemented. MXTC dynamically encodes HXe gas exchange into the image contrast. This permits two parameters to be derived regionally which are related to gas-exchange functionality by characterizing …
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Venous Thrombosis: Formation, Evolution And Resolution Imaging Using Non-Invasive MRI Techniques
… MRI sequences including T1 mapping, T2* mapping, Magnetization Transfer Contrast (MTC), and Apparent Diffusion Coefficients (ADC) maps for the<br/>detection of thrombus in a murine model of deep venous thrombosis. The second aim was to investigate the merit of a fibrin and macrophage specific MR …
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Methods for chemical exchange saturation transfer magnetic resonance imaging
Chemical exchange saturation transfer (CEST) is a relatively new magnetic resonance imaging (MRI) acquisition technique that generates contrast dependent on tissue microenvironment, such as protein concentration and intracellular pH. CEST imaging has the potential to become an important biomarker …
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Towards imaging cerebral microvascular blood flow using MRI
… with aging, named (i) pseudo-continuous transfer insensitive labeling technique (pTILT) and (ii) flow-enhanced signal intensity (FENSI). pTILT is an advanced pseudo-continuous ASL approach which is developed from the traditional pulsed ASL method of transfer insensitive labeling technique …
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On Nature of the Gradient Echo MR Signal and Its Application to Monitoring Multiple Sclerosis
… as research tools to study MS. Among them are magnetization transfer contrast imaging: MT), MR spectroscopy: MRS), and Diffusion Tensor Imaging: DTI) but they have not penetrated to clinical arena yet.</p><p>Gradient Echo Plural Contrast Imaging: GEPCI) developed in our laboratory is a post …
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Promoting and measuring remyelination and neuroprotection in clinical trials of people with multiple sclerosis
The most tractable strategy to delay or prevent the progressive phase of MS is to promote endogenous remyelination; doing so restores nerve conduction and prevents demyelinated axons from degenerating. The rate-limiting stage in this process is differentiation of oligodendrocyte progenitor cells …
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Network-based approaches towards understanding the emergence of neurodevelopmental disorders
… 2}, I define the normative MIND network using magnetization transfer ratio (MTR) and show that it exhibits complex topological properties and aligns with independent measures of cortical cytoarchitectonics, mouse spatial transcriptomics, and tract-tracing. The network was highly reproducible …
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Development of human functional and structural brain networks in adolescence and its relevance to psychiatric disorders
… of cortical thickness, and with increased magnetization transfer, a micro-structural measure of intra-cortical myelination. Regional nodes of the morphometric similarity networks that became more dissimilar, putatively more differentiated in terms of their cyto- and myelo-architectonics …