Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 30 for “"MND"”.
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How can virtual reality benefit the lives of persons with MND?
… for individuals with motor neuron disease (MND) and other disabilities. We developed Stackly, a space-themed stacking game, as an example of how VR-based exercise programs could be designed for this population. The primary objective of the game is to stack cubes in a designated area, …
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„Ég get varla um frjálst höfuð strokið“: Upplifun og reynsla óformlegra umönnunaraðila MS- og MND-sjúklinga
… fullorðinna einstaklinga með annað hvort MS- eða MND-sjúkdóminn. Nánar tiltekið upplifun þeirra og reynslu af veikindunum og hlutverki sem umönnunaraðili. Einnig var kannað hvaða stuðningur hefði staðið þessum einstaklingum til boða og hverjar þarfir þeirra eru fyrir þjónustu. Rannsóknin var …
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The personal experience of carers of individuals with Motor Neurone Disease (MND) and their experiences of services
… a partners diagnosed with Motor Neurone Disease (MND). Lastly, a public domain provides a summary of the empirical paper.
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Population-based genotype-phenotype correlation to stratify incident cases of motor neurone disease in Scotland from 2015-2017
BACKGROUND: Motor neurone disease (MND) refers to a spectrum of rapidly progressive neurodegenerative diseases for which there remains no cure. A recognised and crucial barrier to more accurate diagnosis, prognosis and treatment relates to phenotypic heterogeneity. Recent discoveries in the genetic …
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Endosomal Sorting Complex Required for Transport (ESCRT): Investigation of the expression and functional roles in neurodegenerative diseases
… disease, Parkinson's and Motor Neurone disease (MND). This study investigated the expression of ESCRT proteins in age matched nonneurodegenerative brains, AD brains, MND brains and spinal cord. The levels of ESCRT proteins in MND and AD brains are significantly different relative to age matched …
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Motor neuron disease in an African population: A review of current literature and a case series of the flail arm variant in the Western Cape
Background: Motor neuron disease (MND) is a devastating neurodegenerative disorder, with recognised phenotypic subtypes. Although prevalent in all parts of the world, little is described in the literature with regards motor neuron disease as it occurs in African populations. Aims: This study had …
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A review of cases of motor neurone disease seen at Groote Schuur Hospital from 2005 to 2010
Motor neurone disease (MND) is a rare progressive neurodegenerative disorder in which selective degeneration of the motor neurones of the brain and spinal cord occurs. Progressive weakness of limb, bulbar and respiratory muscles eventually results in death. Most descriptive and epidemiological …
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A qualitative study into the communication surrounding the initiation and withdrawal of non-invasive ventilation (NIV) in people with Motor Neurone Disease
Introduction Motor neurone disease (MND) is a degenerative disease that adversely affects the nervous system and muscular control. Eventually respiratory muscles weaken, causing breathing, communication and swallowing difficulties, and ultimately, respiratory failure and death. Improved quality of …
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Understanding mechanisms related to psychosis in Motor Neurone Disease
… of the syndromes of motor neurone disease (MND), frontotemporal dementia (FTD) and their overlap (FTD-MND). Clinically evident psychosis is not common, except in those with C9orf72+ expansions. However, subthreshold psychosis or pre-psychosis processes are common and provide the opportunity …
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Development and analysis of hierarchical feedforward neural network systems for classification of motor neurone disease based on magnetic resonance spectra
… are associated with Motor Neurone Disease (MND). Magnetic Resonance Spectroscopy (MRS) has been performed on the brains of MND patients and control volunteers to acquire signals which contain information about brain metabolites from within the motor cortex area. Discrimination between JvThD …
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Outcomes of Enteral Feeding in Motor Neurone Disease
Motor Neurone Disease (MND) is a fatal neurodegenerative disease of unknown aetiology characterised by the degeneration of motor neurones leading to progressive wasting and weakness of the bulbar, limb and respiratory muscles. Symptomatic treatment remains the cornerstone of management. …
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Real-time control of a robot using brain activity
Background: Motor neuron disease (MND) describes a range of pathologies in which a person's voluntary muscle control becomes progressively impaired. Whether MND is on-set alone, or - as it commonly would be - paired with muscular atrophy, sufferers of the disease can face difficulty in establishing …
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Myasthenia Gravis mimics: An audit of cases identified at Groote Schuur Hospital over 20 years
… symptoms (FNS), 6 motor neuron disease (MND) variants, 3 mitochondrial cytopathies, 4 had definite or probable muscular dystrophy (MD), 1 progressive supranuclear palsy and 1 with a multiple sclerosis brainstem relapse. Median age at symptom onset was 10 years for CMS, 18 for …
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Phosphoglycerate kinase 1 as a therapeutic target in motor neuron disease
… conditions like motor neuron disease (MND) and supporting cell energy production is an attractive strategy to improve the resilience of neurons to disease pathology. Phosphoglycerate kinase 1 (PGK1) is a key enzyme in the first ATP-producing step in the glycolysis pathway. PGK1 may have …
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Perceptions of cause and control in people with Parkinson's disease
… sclerosis (MS) and motor neurone disease (MND). Age, gender and disease duration were not found to be consistently related to control. However perceptions of control were associated with some measures of disease stage/disability. Furthermore, increased perception of certain types of …
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Engaging with Motor Neurone Disease
… in the context of Motor Neurone Disease (MND). To do this, I use interviews and observations to explore how experiences are shaped and situated. By connecting geography, science studies, disability and applied health research, the project brings together debates around spaces and bodies. …
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Defining the genetic and molecular pathways underlying motor neuron degenerative diseases
Motor neuron degenerative diseases (MNDs) are a large group of genetically and clinically heterogeneous life-limiting disorders. MNDs are characterised by the progressive degeneration of upper and/or lower motor neurons. Unfortunately, there are currently no universal biomarker assays or …
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The involvement of free radicals in the casual mechanism of Motor Neurone Disease
… neurones associated with motor neurone disease (MND) may be due to acute or chronic free radical damage causing irreversible cell lesions. Perturbation in the mechanisms involved in the cell's protection against the deleterious effects of free radicals could therefore initiate, or indeed …
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Investigating the role of eEF1A2 in motor neuron degeneration
… in spinal cords from human motor neuron disease (MND) patients. Preliminary data suggests that motor neurons from some MND patients express significantly less eEF1A2 than motor neurons of control samples. Further work is required to confirm these findings. Finally, I investigated the individual …
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AN ANALYSIS OF THE TAIWAN NAVY MINEHUNTER PROCUREMENT FRAUD CASE
… of Taiwan Ministry of National Defense (MND), First Bank, and Ching-Fu’s fraudulent loan activities. The alleged incidents detailed in the investigation report and publicly available resources are aligned with contract management processes, internal control components, and procurement …
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