Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 60 for “"MAF"”.
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Maf and Mitf transcription factors regulate pancreatic endocrine cell differentiation and function
… of transcription factors. Two of these factors, MafA and MafB, have been shown to play a major role in the regulation of several genes critical to pancreas development and endocrine cell formation. MafB is essential for both α- and β-cell differentiation, as mice lacking MafB have fewer insulin+ …
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IDENTIFYING, CHARACTERIZING AND VERIFYING NOVEL C-MAF FUNCTIONS IN T CELL DEVELOPMENT AND APOPTOSIS
… is to investigate the mechanisms underlying c-Maf mediated control of developing and mature T cells. c-Maf, a basic leucine zipper transcription factor, is well known for its ability to promote T helper 2 (Th2) differentiation by direct transactivation of IL-4 following interaction with a …
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Characterization of a Novel Nuclear Variant of Bmp2 and Coordinate Regulation of Col11a2 and Col27a1 by the Transcription Factor Lc-Maf
… AND COL27A1 BY THE TRANSCRIPTION FACTOR LC-MAF<br /><br /> During skeletal development, long bones of the body develop from a cartilage template that is progressively replaced by bone. This process of endochondral ossification requires precisely coordinated expression of extracellular matrix …
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Understanding T cells in type 1 diabetes: a role for c-Maf and characterization of intracellular signaling following engagement of transgenic Ly49A.
… the mechanisms underlying defective c-Maf binding to the IL-4 promoter in T cells from diabetes prone mice and identify the mechanisms responsible for suppression of T cells by the inhibitory receptor Ly49A. It is not clear why development of protective Th2 cells is poor in T1D. c-Maf …
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Production and Flow Cytometric Identification of Triploid Walleyes
… were conducted: 3SoC-10 min after fertilization (MAF)-1. 0 min, 3SoC-10 MAF-2.0 min, 400C-10 MAF-1.5 min, and 120C-10 MAF-1.5 min (control treatment). The heat-shock treatments of 3SoC-10 MAF-2.0min and 400C-10 MAF-1.5 min were lethal to walleye eggs acclimated to 120C. Total percent hatch for the …
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Transient method of characteristics via the Adiabatic, Theta, and Multigrid Amplitude Function methods
… Theta, and Multigrid Amplitude Function (MAF) methods for solving the Method of Characteristics (MOC) formulation of the time-dependent neutron transport equation. The transient transport versions of the 2D LRA and C5G7 benchmarks were used to assess the performance and accuracy of these …
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Caractérisation hydraulique des méthodes hydrologiques des débits réservés pour les habitats aquatiques
… en fonction du débit (débit annuel moyen (MAF), MAF de 30 % et MAF de 10 %). Un modèle de simulation du profil de la surface de l'eau a été utilisé pour comparer les résultats observés avec ceux obtenus à partir des fonctions de puissance. Les caractéristiques hydrauliques des rivières sont …
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Splenic Regulation Of Macrophage Activity In Mice Infected With Listeria Monocytogenes
… the production of macrophage activation factor (MAF) or both. A possible role for MIF, MAF, and B cells is discussed.
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A substructure synthesis formulation for vibration isolation
… convergence to the exact eigenvalues. The MAF-SS formulation results in explicit knowledge of the constraints coupling substructures. Changing these constraints with active feedback results in a modified structure. The effect of active feedback of terms proportional to the coupling …
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Strategies to maximize feed quality and poultry performance
… feed mills utilize low mixer-added fat (MAF) to increase ingredient binding opportunities and pellet quality, but this technique may decrease feed nutrient digestibility. In Chapter 2, two experiments were conducted in order to determine the best feed manufacture technique (MTECH) to …
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PRINTING MUCOADHESIVE AND ORODISPERSIBLE FILMS FOR THE PERSONALIZATION OF THERAPY
… films (ODF) and mucoadhesive films (MAF) are increasingly recognized as valuable tools for addressing unmet therapeutic needs in populations requiring flexible, easy-to-administer medicines, such as paediatric and dysphagic patients. Among the proposed manufacturing techniques, …
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Identification and analysis of Il-2 induced Stat5 Target genes in Human CD4 and CD8 T cells
… lineage-specification factors, c-MAF and RORA. Given the importance of IL-2 in<br/>facilitating CD4 Th2 cell differentiation, the regulation of c-MAF by STAT5 was<br/>functionally characterised further using biochemical and molecular techniques. These<br/>studies revealed that the …
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Human host and malaria parasite genome variations to susceptibility to malaria
… the analysis of the minor allele frequency (MAF) proportion of all pharmacogenes variants obtained from the databases revealed that a high proportion of common variants (MAF > 0.05) of pharmacogenes were higher in the four African population from malaria endemic areas (MAF proportion > 50%) …
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The Effect of Hydrogen Partial Pressure on Lignite Liquefaction in a Two-Stage Hot-Charge Batch Autoclave System
… and fifty grams of moisture- and ash-free (MAF) Zap lignite, three hundred grams of AO4 (Anthracene oil) solvent and seventy five grams of water were reacted in the autoclave unit. Carbon monoxide was used as feed gas for the first stage and varying amounts of hydrogen and carbon monoxide …
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수탁기관에 의뢰된 검체의 철 결핍 진단을 위한 지표 평가
… evaluated: MCV, MCHC, MCH, CHr, %Hypo, MRV, Rsf, Maf, LHD%, soluble transferrin receptors(sTfR) and body iron. Comparing control with ID group, %Hypo and body iron showed AUC over 0.9 with cutoff of 20.3 and 7.57 mg/kg, respectively. Comparing IDA group ACD group, MCH showed the largest AUC, which …
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Μελέτη πολυμορφισμών στα γονίδια του συστήματος του συμπληρώματος C2, C3 και Bf που ενέχονται στην ανάπτυξη της ηλικιακής εκφύλισης της ώχρας κηλίδας στον ελληνικό πληθυσμό
… C>G) [ελάσσονος αλληλίου:minor allele frequency (MAF)], ήταν σημαντικά υψηλότερη στους ασθενείς με AMD σε σύγκριση με τους μάρτυρες (0.34 έναντι 0.22, P=0.0031) και παρόμοια με τη συχνότητα άλλων πληθυσμών που έχουν ήδη δημοσιευτεί. Υπήρχε σημαντική διαφορά στις συχνότητες των rs2230199 γονοτύπων …
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Impact of Kras/Nras Mutational Heterogeneity On Clinical Outcomes In Colorectal Cancer
… the role of relative mutant allele frequency (rMAF) as a biomarker.</p> <p><strong>Methods: </strong>Using institutional and public cohorts of mCRC patients with NGS results, we described the prevalence and clinical impact of atypical (not in current guidelines) and low rMAF <em>RAS</em> …
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Autoclave Studies of Lignite Liquefaction
… contain ing 200 grams of moisture-ash-free (MAF) lignite, 100 grams of water, and 400 grams of hydrogenated anthracene oil solvent was fed into the University of North Dakota Time-Sampling Hot-Charge Batch Autoclave System with the gas at an initial pressure of 400 psig.</p><p>Oil yields and …
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Identification of novel coding single nucleotide polymorphisms associated with acute respiratory distress syndrome
… susceptibility to ARDS[minor allele frequency (MAF): 0.219 versus 0.003 (control), p<2.95×10-7 and 0.386 versus 0.046 (control), p<2.95×10-7; respectively]. rs3848719 (MAF 0.394 in cases, 0.287 in controls) is associated with APACHE II score when the score quartiles are compared (p=0.032 …
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