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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 20 of 22 for “"M-CSF"”.

  1. Progesterone Enhances Macrophage Colony-Stimulating Factor(M-CSF) Production in Human Endometrial Stromal Cells in vitro

    Hatayama, HiroshiKyoto University1995

    本文データは平成22年度国立国会図書館の学位論文(博士)のデジタル化実施により作成された画像ファイルを基にpdf変換したものである

    kyoto Repository record

  2. Tumor Angiogenesis is all Tied up in Tie2-Expressing Macrophages

    Forget, Mary A.The Ohio State University2012

    … growth, angiogenesis and tumor metastasis. M-CSF is known to promote tumor vessel growth and progression through the production of angiogenic factors like VEGF. In the second part of this study, we demonstrate that M-CSF can modulate Tie2 receptor expression on macrophages both in vitro and in …

    ohiolink Repository record

  3. Endovascular trophoblast cell behavior in normal and abnormal pregnancy

    Endo, YasuhiroVirginia Tech1995

    … of macrophage-colony stimulating factor (M-CSF) on human trophoblast cells were examined. While term trophoblast cells did not respond to M-CSF, those from early trimester and choriocarcinoma cells showed enhanced growth after treatment. In addition, the serum level of M-CSF in hypertensive …

    vt Repository record

  4. In vitro Differenzierung von Monozyten der Zelllinine RAW 264.7 zu Osteoklasten, deren Charakterisierung und Wechselwirkung mit Osteoblasten

    Lesky, ThomasTechnische Universität Dresden

    … in Gegenwart von M-CSF seine osteoklastenstimulierende Wirkung entfalten. Der ebenfalls von Osteoblasten gebildete „decoy“-Rezeptor OPG blockiert als freies Protein durch Bindung an RANKL dessen Interaktion mit RANK und verhindert somit die Osteoklastogenese und …

    qucosa-diss

  5. Periventricular white matter damage in the post-natal brain in hypoxic conditions

    DENG YIYU2009

    … and macrophage-colony stimulating factor (M-CSF) expression was observed. Immunoexpression of these was specifically located in AMC from 24h-7d. However, CSF-1 receptor (CSF-1R), TNF-a and IL-1ß immunoexpression was increased in the astrocytes from 7-14d. TNF receptor 1 (TNF-R1) and IL-1 …

    nus Repository record

  6. Adult Human Microglia: Phenotypic Diversity and Functional Complexity

    Smith, AmyResearchSpace@Auckland2013

    … Macrophage Colony-Stimulating Factor (M-CSF) promoted a distinct microglial phenotype with increased PU.1 expression, and induced microglia to proliferate and undergo phagocytosis. Conversely, interferon-y (IFNy) induced an activated microglial phenotype with increased Human Leukocyte …

    auckland-ms Repository record

  7. Involvement of Histone Deacetylase 4 (HDAC4) in Osteoclast Function

    Faulkner, Bora2019

    … from impaired signaling downstream of the M-CSF and v3 integrin and diminished M-CSF mediated adhesion and migration. Moreover, I demonstrated that c-Src activation in osteoclasts is regulated by HDAC4. The results of this thesis have identified HDAC4 as an essential regulator of osteoclast …

    umn Repository record

  8. Studies of the role of nf-κb in controlling osteoclast differentiation and bone loss

    Yao, Z.University of Westminster2016

    … of macrophage colony stimulating factor (M-CSF) receptor, c-Fms, and switching M-CSF-induced resident (M2) to inflammatory (M1) macrophages with enhanced OC forming potential and increased production of inflammatory factors through induction of NF-κB RelB; 2) Similar to RANKL, TNF …

    westminster Repository record

  9. Role of Macrophages in Ocular Surface Fibrosis

    Corpuz, Alyanna

    … <p>Bone marrow cells were cultured in M-CSF to obtain M0 macrophages, which were subsequently polarized into M1 and M2 phenotypes using IFN-g + LPS and IL-4, respectively.</p> <p>The macrophages were exposed to 7 Gy radiation. The effect of irradiation on macrophage activation markers, …

    chapman Repository record

  10. Tumor-induced macrophage and T cell dysfunction

    Walker, Thomas M.Virginia Tech1995

    … to MΦ colony-stimulating factor (M-CSF). M-CSF did not reverse decreases in autorecognition caused by TBH MΦ, and increased TBH MΦ suppression during T-cell alloreactivity. TBH suppressor activities were associated predominantly with MHC class II MΦ. TBH class II⁻ MΦ quantitatively …

    vt Repository record

  11. Characterization of the Developmentally Regulated Osteoclast Support Potential of In Vitro Medullary Adipocytes

    Holt, Vance Edward Troupe, IIICase Western Reserve University School of Graduate Studies2013

    … in osteoclast development including RANKL, M-CSF and OPG were expressed by in vitro medullary adipocytes. Furthermore, the expression of these important osteoclast mediators was only observed in a specific population of previously unidentified medullary adipocytes at a particular stage of …

    ohiolink Repository record

  12. Kinetics of notch signaling during osteoclastogenesis

    Framstad, Amber Larissa

    … of Macrophage Colony Stimulating Factor (M-CSF). This pathway consists of four membrane bound receptors and 5 membrane bound ligands including Jagged1 which is known to play a role in cell-cell communication between a variety of cell types including osteoclasts and osteoblasts. Notch …

    eastern-wash Repository record

  13. Integrin-ligand interactions and cytokine production by monocytic cells

    Edkins, Adrienne LesleyUniversity of Glasgow2008

    … of macrophage colony stimulating factor (M-CSF) and partially inhibited by an anti-TLR-2 antibody. Chronic stimulation (<3 days) of THP-1 cells with the anti-αVβ3 antibody in the presence of M-CSF led to morphological changes in the cell line associated with the development of a more …

    glasgow Repository record

  14. Vaccinia Virus Binding and Infection of Primary Human Leukocytes

    Byrd, Daniel James2014

    … macrophage colony-stimulating factor (GM-CSF)-polarized M1 and macrophage colony-stimulating factor (M-CSF)-polarized M2, were permissive to VV replication. The majority of virions produced in MDMs were extracellular enveloped virions (EEV). Visualization of infected MDMs revealed the …

    iupui Repository record

  15. Characterising the role of Valosin Containing Protein (VCP) in autophagy and cell differentiation.

    Budnik-Zawilska, MilkaUniversity of East Anglia2015

    … mutations are hyper-responsive to RANKL and M-CSF treatment. This suggests that under normal homeostasis VCP plays an important role in regulating the response of osteoclasts to bone microenvironment. However, the mechanisms by which VCP mutations stimulate osteoclast differentiation in Paget …

    east-anglia Repository record

  16. Les Récepteurs nicotiniques de l'acétylcholine modulent la production et la distribution des monocytes pro-inflammatoires

    St-Pierre, StéphanieUniversité de Moncton2017

    … par stimulation de la moelle osseuse ex vivo (M-CSF+IFNy) en réduisant leur prolifération et viabilité sans affecter les neutrophiles. Les sous-unités prédominantes dans la moelle osseuse sont l'α7 et l'α9, dont l'implication a été testée. Les effets de la nicotine sur le nombre de …

    moncton Repository record

  17. Monozyten-Populationen und ihre Zytokin-Produktion beim Erysipel

    Horelt, AlexiaLudwig-Maximilians-Universität

    … und Macrophage-Colony-Stimulating-Factor (M-CSF)- Serumspiegel auf. Unter diesen klinischen Entzündungsparametern korrelierten am Tag 1 nur die Körpertemperatur und der CRP-Spiegel signifikant mit den Zellzahlen der CD14+CD16+ Monozyten. Außerdem wurde die Tumornekrosefaktor (TNF)- Produktion …

    lmu-germany Repository record

  18. Phenotypic and Functional Characterisation of Hofbauer Cells Across Gestation

    Appios, AnnaUniversity of Cambridge2022

    … cultures demonstrated the importance of M-CSF for driving key features of the HBC phenotype. In summary, the results presented in this thesis provide an in-depth characterisation of HBC and how they change across gestation to aid placental function in a healthy pregnancy.

    cambridge Repository record

  19. Le rôle de DUSP4 dans l'athérosclérose

    Fouere, DonovanUniversité de Sherbrooke2021

    … l’expression de DUSP1, IL-1a, CCL2 et M-CSF. En conclusion, nos résultats ont permis de montrer que la délétion de DUSP4 entraine une diminution de l’athérosclérose et que le palmitate induit l’activation de p38 et ERK dans les macrophages. Le rôle de DUSP4 et du palmitate reste encore à …

    sherbrooke Repository record

  20. Herstellung und Charakterisierung monoklonaler Antikörper gegen die Anaphylatoxin-Rezeptoren

    Kiafard, Ziba2012

    … und auf Makrophagen, die mittels M-CSF aus Knochenmarksvorläuferzellen differenziert wurden, exprimiert wird. Auf neutrophilen Granulozyten konnte keine C3aR-Expression nachgewiesen werden. Dendritische Zellen aus murinem Knochenmark zeigten eine schwache C3aR-Expression. Die …

    goettingen Repository record

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