Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 28 for “"Lp(a)"”.
-
Interaktion von nativem und oxidiertem Lp(a) mit menschlichen Mesangialzellen und Matrix
Das Mesangium sowie Lipoproteine wie LDL und Lp(a) spielen in der Pathologie vieler renaler Erkrankungen eine entscheidende Rolle. Die Bindung, Internalisierung und der intrazelluläre Abbau von nativem und oxidiertem LDL in menschlichen Mesangialzellen und an der mesangialen Matrix wurden …
-
BReach-LP: a Framework for Backward Reachability Analysis of Neural Feedback Loops
… non-convex settings, this thesis proposes BReach-LP: a set of techniques to conduct backward reachability analysis for NFLs. While backward reachability analysis has been studied for systems not containing NNs, the general noninvertability of NNs makes backward reachability analysis for NFLs a …
-
The effects of an eight week cardiac rehabilitation exercise program on Lp(a) concentration in patients with coronary artery disease
Elevated lipoprotein (a) concentration (Lp(a)) ($>$30 mg/dl particle mass) is an independent risk factor for coronary artery disease (CAD). It has been suggested that intense exercise lowers plasma (Lp(a)) in healthy individuals. To study the efficacy of moderate intensity exercise in lowering …
-
Lipoprotein(a) and the risk of vascular disease
Background: Lipoprotein(a) [Lp(a)] is composed of a low density-lipoprotein (LDL) particle and a glycoprotein molecule known as apolipoprotein(a) [apo(a)]. Apo(a) exists in several differently-sized isoforms and is responsible for the unique properties of Lp(a). Although Lp(a) has been known for …
-
Συσχέτιση της διαταραχής της στεφανιαίας μικροκυκλοφορίας με εργαστηριακά ευρήματα σε ασθενείς με στηθάγχη χωρίς αποφρακτική στεφανιαία νόσο / Association of coronary microvascular dysfunction with laboratory findings in patients with angina with non-obstructive coronary artery disease
… δεδομένα σχετικά με τη λιποπρωτεΐνη(a) [Lp(a)] είναι περιορισμένα. Στόχοι: Η παρούσα συγχρονική μελέτη είχε ως στόχο να διερευνήσει εάν τα επίπεδα της Lp(a) σχετίζονται με την CMD σε ασθενείς με στηθάγχη χωρίς αποφρακτική στεφανιαία νόσο (ANOCA). Δευτερεύοντα καταληκτικά σημεία …
-
Lipoprotein(a) in vascular health: its role in inflammation, atherosclerosis, and arterial function
Η λιποπρωτεΐνη(α) [Lp(a)] είναι ένα μοναδικό σωματίδιο λιποπρωτεΐνης που παίζει σημαντικό ρόλο στην καρδιαγγειακή υγεία και νόσο. Δομικά, η Lp(a) αποτελείται από ένα κεντρικό σωματίδιο παρόμοιο με τη χαμηλής πυκνότητας λιποπρωτεΐνη (LDL), το οποίο είναι συνδεδεμένο ομοιοπολικά με μια γλυκοπρωτεΐνη …
-
The Role of Lipoprotein(a)/Apolipoprotein(a) in Endothelial Dysfunction: Mechanistic Studies in Vascular Endothelium
… suggest that elevated plasma lipoprotein(a) (Lp(a)) concentrations are a significant risk factor for the development of a number of vascular diseases including coronary heart disease and stroke. Lp(a) consists of a low-density lipoprotein (LDL)-like moiety and an unique glycoprotein, …
-
Importancia de la lipoproteína (a) en pacientes con hipercolesterolemia familiar para prevenir el riesgo cardiovascular
… familiar (HF) y valores elevados de Lp(a) tienen un doble riesgo de padecer enfermedades cardiovasculares (CV). Con esta investigación se pretende comprobar, si sería importante aprovechar los cribados en cascada familiar de HF para obtener también los niveles de Lp(a). Para ello, se …
-
Βιβλιογραφική ανασκόπηση κλινικών μελετών που εξετάζουν το ρόλο της λιποπρωτεΐνης α (Lpa) στην καρδιαγγειακή νόσο / The role of lipoprotein (a) in cardiovascular disease: a literature review of clinical evidence
Τα αποτελέσματα της λιποπρωτεΐνης (α), (Lp(a), έχουν συσχετιστεί γενικότερα με αυτά της καρδιαγγειακής νόσου (CVD), μεταξύ των γενικών πληθυσμών. Ωστόσο, η σχέση μεταξύ των αποτελεσμάτων της Lp(a) και καρδιαγγειακού κινδύνου λόγω αθηρωμάτωσης (Atherosclerotic Cardiovascular Disease - ASCVD) σε …
-
USE OF MULTIPLE ANALYTIC APPROACHES TO IDENTIFY NEW MARKERS/RISK FACTORS FOR CARDIOVASCULAR DISEASES AND EVALUATE THEIR ROLE AS POSSIBLE PHARMACOLOGICAL TARGETS
… un'elevata concentrazione di lipoproteina(a) [Lp(a)] rappresenta un fattore di rischio indipendente per le malattie cardiovascolari. Tuttavia, non sono ancora disponibili terapie approvate per i pazienti con livelli elevati di Lp(a). Inoltre, l'ASCVD è una malattia a componente infiammatoria. …
-
Oxidative Modifications of Apolipoprotein(a): Implications for Proinflammatory and Prothrombotic Roles of Lipoprotein(a) in the Vasculature
Elevated plasma concentrations of lipoprotein(a) (Lp(a)) have been identified as a causal risk factor for calcific aortic valve disease (CAVD) and coronary heart disease (CHD). Relationships have recently been identified for genetic factors, such as single nucleotide polymorphisms (SNPs) in the LPA …
-
The effect of anabolic-androgenic hormones on postprandial triglyceridaemia and lipoprotein profiles in man
… LDL and HDL particle size, and LDLC, HDLC and Lp(a) concentration were compared in male (n=9) and female (n=3) bodybuilders after self administration of AAS for 5-6 weeks (ON cycle) and again after a 4-6 week 'washout' period (OFF cycle), and in normal males (T) (n=10) before and during a …
-
LIPID-RELATED CORONARY RISK PROFILE IN SINGAPORE NEWBORNS : RACIAL AND MOLECULAR GENETIC ASPECTS
… lipoprotein, apolipoproteins and lipoprotein(a) [Lp(a)] levels have been established as risk factors for CAD. The adult population of Singapore has shown ethnic specific plasma lipid profiles in accordance to their relative level of coronary risk. This study was designed to look into the profile …
-
The Effects of Flaxseed SDG on Perimenopausal Women with Mild Hyperlipidemia
… trend for improvement of lipid values for LDL-C, Lp(a), and hsCRP while on the Brevail SDG and an improvement of Total Cholesterol, HDL-C, and Non-HDL-C at the six week washout period. The Psyllium group showed a trend for improvement of total Cholesterol, LDL-C, Non-HDL-C, and hsCRP while on the …
-
Untersuchung der Effektivität, Selektivität und Verträglichkeit von DALI-LDL-Apherese bei hohen Blutflüssen
… Selektivität und Effektivität der LDL-C und Lp(a) Reduktion stellten in diesem Zusammenhang die zu untersuchenden Faktoren dar. Das Patientengut bestand aus 13 Patienten mit chronischer Hypercholesterinämie und symptomatischer Atherosklerose die in 7 verschieden Zentren deutschlandweit …
-
The role of lipoproteins in vascular calcification and plaque stabilisation
… (VLDL) density lipoproteins and lipoprotein (a) (Lp(a)), have been previously studied in their relationship to general plaque growth and progression, their roles in influencing plaque calcification are less understood due to experimental variations within the literature. This thesis therefore aims …
-
Biomarcadores relevantes para diagnóstico precoce e prevenção de doenças cardiovasculares.
… are under discuss ion . CRP, homocysteine , Lp (a) Lp - PLA2 and MPO act in pathophysiological mechanisms stimulating the atherogenic and thrombogenic process. The measurement of D - dimer represents the formation and degradation of the fibrin clot in the dynamics of blood coag ulation. …
-
Ο ρόλος της λιποπρωτεΐνης (α) και του λιπιδαιμικού profile επιτόκων στην προεκλαμψία
… υποομάδα εγκύων διαπιστώθηκε συνύπαρξη αυξημένης Lp(a) και υψηλού ratio. Η ταυτόχρονη παρουσία αυτών των παραγόντων υποστηρίζει την υπόθεση συνεργιστικής επιβάρυνσης του ενδοθηλίου. Συμπερασματικά, η μελέτη υποδεικνύει ότι η προεκλαμψία δεν αποτελεί αποκλειστικά διαταραχή της πλακουντιακής …
-
Coronary Heart Disease Risk Factors in Schoolchildren Aged 12 to 13 Years of Differing Socio-Economic Status
… (TG) (mmol-L<sup>-1</sup>), lipoprotein(a) (Lp(a)) (mg-dL<sup>-1</sup>), glucose (Glu) (mmol-L<sup>-1</sup>), fibrinogen (Fg) (mg-dL<sup>-1</sup>), folate (ng-mL<sup>-1</sup>), vitamin Bn (pmol-L<sup>-1</sup>), and homocyst(e)ine (Hcy) (μmol-L<sup>-1</sup>) were measured for haematological …
Page 1 of 2