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Showing 1 to 6 of 6 for “"LSEC"”.
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Die pathophysiologische Rolle der Infektion von sinusoidalen Endothelzellen der Leber mit murinem Zytomegalievirus
… konnten sinusoidalen Endothelzellen der Leber (LSEC) als sessile antigenpräsentierende Zellen (APC) identifiziert werden. LSEC sind in der Lage, systemische antigenspezifische Immuntoleranz in CD8+-T-Zellen zu induzieren. Im Zuge der Dissertation sollte nun untersucht werden, welche …
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Immunbiologie hepatischer Natürlicher - Killer T- (NKT-) Zellen
Sinusoidalen Leberendothelzellen (LSEC) induziert unter physiologischen Bedingungen systemische Immuntoleranz in T - Zellen. Dennoch finden effektive Immunreaktionen gegenüber Pathogenen und Tumoren innerhalb der Leber statt. Wahrscheinlich sind Natürlichen Killer T- (NKT-) Zellen, wesentlich an …
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Optimization of primary endothelial culture methods and assessment of cell signaling pathways in the context of inflammation
… of primary liver sinusoidal endothelial cells (LSEC) was initially studied due to the high metabolic requirements of the liver, as well as the unique phenotype that they possess. We were able to demonstrate that free fatty acids were able to rescue LSEC in culture, promote proliferation, and …
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The Design and Assembly of 3D Liver Mimetic Cellular Architectures
… liver sinusoidal endothelial cells denoted as hLSECs and rLSECs respectively, and an intermediate chitosan-hyaluronic acid (HA) polyelectrolyte multilayer (PEM). The height of the PEMs ranged from 30-55nm and exhibited a shear modulus of ~ 100kPa. Primary rat hepatocytes coated with 5 and 15 PE …
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Angiogenic growth factors and notch signaling regulate liver sinusoidal endothelial cell phenotype in combination with matrix stiffness and ECM composition
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2025-10-19 without embargo terms
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Deconstructing the influences of combinatorial microenvironmental cues on human non-parenchymal liver cells in models of liver fibrosis
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2024-05-01