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Showing 1 to 8 of 8 for “"LIVER PERFUSION"”.
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The first-pass extraction of pindolol in comparison with propranolol in rat liver
… conditions by means of an isolated rat liver perfusion model.
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Meeting the oxygen requirements of an isolated perfused rat liver
Liver perfusion systems can be used as organ culture platforms for metabolic, genetic and systems engineering, tissue regeneration, pharmacokinetics, organ storage and marginal donor reconditioning for transplantation. The primary requirement of such a system is that it maintain ex vivo organ …
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Energy Homeostasis During Fasting and Fed States: Foxa2 Regulates Hepatic Amino Acid Uptake
… We also examined the regulation of mNAT3 in the liver. The liver is the main site for gluconeogenesis during fasting, and has been shown to increase amino acid uptake during periods of low nutrient intake to increase its substrate pool for glucose production. We found that mNAT3 is upregulated …
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Characterisation of Anti-Apoptotic Signalling Pathways in Hepatocytes activated by alpha-Lipoic Acid and Atrial Natriuretic Peptide
… hepatocytes and ischemic isolated perfused rat livers. alpha-lipoic acid was shown to protect isolated hepatocytes from TNF-alpha-/ActinomycinD-induced apoptosis. Astonishingly, this effect did not seem to be governed neither by its well described antioxidative nor its Fe-chelating properties. …
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The Orotic Aciduria of Chemical Hepatotoxicity (Liver Disease, Alcohol, Galactosamine)
… orotic aciduria in rats: chemical damage to the liver by (1) carbon tetrachloride, (2) ethanol, (3) galactosamine, (4) partial removal of the liver, and (5) meal feeding by growing animals. Orotic acid excretion also depends upon: the dietary lysine/arginine ratio, and blood ammonia …
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Design of Lipid and Polymeric Carriers for Nucleic Acid Delivery
… lipid and polymeric carriers for nucleic acid delivery. These included: i) to develop novel cationic lipids for plasmid, oligonucleotide, and siRNA delivery; ii) to develop a novel polymeric delivery system, polyethylene glycol (PEG) based bio–conjugate, for oligonucleotide delivery; iii) to …
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ΕΠΙΔΡΑΣΗ ΤΗΣ ΓΛΥΚΟΖΗΣ ΚΑΙ ΤΗΣ ΙΝΣΟΥΛΙΝΗΣ ΣΤΟ ΜΕΤΑΒΟΛΙΣΜΟ ΤΟΥ ΓΛΥΚΟΓΟΝΟΥ ΤΟΥ ΗΠΑΤΟΣ
ΚΑΤΑ ΤΗ ΔΙΑΠΟΤΙΣΗ ΑΠΟΜΟΝΩΜΕΝΟΥ HΠΑΤΟΣ ΦΥΣΙΟΛΟΓΙΚΟΥ ΚΑΙ ΔΙΑΒΗΤΙΚΟΥ ΕΠΙΜΥΟΣ ΜΕ ΗΜΙΣΥΝΘΕΤΙΚΟ ΜΕΣΟ ΔΙΑΠΟΤΙΣΕΩΣ, ΜΕΛΕΤΗΘΗΚΕ Η ΕΠΙΔΡΑΣΗ ΤΗΣ ΓΛΥΚΟΖΗΣ ΚΑΙ ΙΝΣΟΥΛΙΝΗΣ ΣΤΟ ΜΕΤΑΒΟΛΙΣΜΟ ΓΛΥΚΟΓΟΝΟΥ ΗΠΑΤΟΣ. ΤΑ ΑΠΟΤΕΛΕΣΜΑΤΑ ΣΥΝΟΨΙΖΟΝΤΑΙ ΣΤΑ ΕΞΗΣ: 1)Η ΓΛΥΚΟΖΗ ΠΡΟΚΑΛΕΙ ΜΙΚΡΗΣ ΔΙΑΡΚΕΙΑΣ ΕΝΕΡΓΟΠΟΙΗΣΗ ΤΗΣ ΣΥΝΘΕΤΑΣΗΣ …