Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 19 of 19 for “"KCs"”.
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Tear lacritin concentrations in canine keratoconjunctivitis sicca
Background: Keratoconjunctivitis sicca (KCS) is a chronic ocular disease of both dogs and humans that can result in ocular discomfort, corneal opacification, and vision loss. Lacritin, a protein found in the tears of many species, has been shown to play a role in lacrimation and corneal health. …
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Neurogenese, Wachstum und Integration von lokalen Nervenzellen in einem multisensorischen Neuropil im zentralen Gehrin adulter Insekten.
… lokale Interneurones, die Kenyon Zellen (KCs). In den erwachsenen Grillengehirnen - im Gegensatz zu anderer Insektsorte- nur wird eine Gruppe von KCs ununterbrochen eben von fortbestehenden neuroblasts während des Erwachsenlebens gebildet. Diese wachsen und unterschiedene Neuronen müssen …
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KUPFFER CELLS¿ MITOCHONDRIAL PLASTICITY AFFECTS SYSTEMIC IMMUNO-METABOLISM
BACKGROUND: Kupffer cells (KCs) are hepatic resident macrophages that are essential for liver physiology and contribute to the development of metabolic-associated fatty liver disease (MAFLD). Due to their high plasticity, KCs can maintain immunotolerance and mediate cell-cell interaction within the …
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Linear control model of the spinal processing of descending neural signals
… into a set of Kinematic Control Synergies (KCS), which have simple, orthogonal kinematic functions. Activating these KCS with simple pulse-like signals allows for the formation of a wide range of behaviors. It is hypothesized that such signals might come from higher-level Central Nervous …
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Precision location of additively manufactured components using integral kinematic couplings
… In this thesis, integral kinematic couplings (KCs) are shown to provide precision location of AM components. Maxwell KCs are fabricated using four common AM processes for characterization of their accuracy, repeatability, and stiffness. Modest plastic deformation at the locations of (point) …
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Knowledge used for teaching counting: A case study of the treatment of counting by two Grade 3 teachers situated in schools serving working class communities in the Western Cape Province of South Africa
… (ii) Teacher's Knowledge of Content and Student (KCS); and (iii) teacher's Knowledge of Content and Curriculum (KCC). Teachers' KCS was considered in this study as it concerns what teachers know about what learners know and how they learn. The general interest of this project was to study the …
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The Design of Three-Dimensional Multicellular Liver Models Using Detachable, Nanoscale Polyelectrolyte Multilayers
… endothelial cells (LSECs), and Kupffer cells (KCs). LSECs and KCs in the liver model were separated from hepatocytes by a nanoscale, detachable, optically transparent chitosan and hyaluronic acid (HA) polyelectrolyte multilayer (PEM) film. The properties of the PEM were tuned to mimic the Space …
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Defining Gene Expression in Normal Human Epidermal Keratinocytes and Melanocytes: A Prerequisite for Understanding Hyperplastic and Neoplastic Pathology
… epidermis. Even short-term suspension culture of KCs (used for FACS) altered gene expression. Established primary KCs in culture express some genes, e.g., keratin 16, at levels found in pathologic states such as psoriasis. Currently limited by LCM methodology, the identification of melanocyte was …
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Manufacturability of lab on a chip devices: tolerance analysis and requirements establishment
… were found. Design considerations in the system KCs were suggested in order to minimize the effect of variation and reduce the risk of failure.
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Engineering complex liver models for drug screening and infectious diseases: a biomaterials and co-culture perspective
… liver NPCs, such as primary human Kupffer cells (KCs), were incorporated into the MPCC model since KCs play key roles in immune responses and inflammation. This work will be used to establish models that integrate multiple liver cell types on a physiologically-relevant substrate to study disease …
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Octopaminergic Regulation of Olfactory Discrimination in the Drosophila Larval Mushroom Body Calyx
… (PNs). Mushroom body neurons, Kenyon cells (KCs), integrate these inputs through a combinatorial coding mechanism that allows discrimination among them. The calyx is innervated by extrinsic neurons that regulate its activity; these include two octopaminergic (OA) SEZ Ventral Unpaired Median 1 …
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Role of High Molecular Weight Hyaluronan in Ultraviolet B Light-Induced Transformation
Keratinocyte carcinomas (KCs) are the most common cancers globally. Ultraviolet light is the key risk factor for these cancers but sunscreen has proven ineffective in their prevention, indicating a need for new prophylactic agents. Chronic elevation of high molecular weight (HMW) tissue hyaluronan …
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Secretomotor substances in the rat lacrimal gland: Immunocytochemical functional and ligand binding studies
… of the disease state keratconjunctivitis sicca (KCS). However, there is no evidence as to whether age-related changes occur in the innervation pattern ofthe lacrimal gland. This study employs histochemical and immunocytochemical techniques to elucidate and compare the occurrence and precise …
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Mechanistic Connectomics in Drosophila
… neurons (PNs) connect onto Kenyon Cells (KCs), the intrinsic neurons of the MB: there are two subsets of PNs with random connectivity, but two PN populations with over- and under-represented connectivity. This finding is replicated within and between brains, and is also present between the …
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Variation propagation modelling and cost-oriented process optimisation for aircraft assembly
… to achieve all assembly Key Characteristics (KCs) simultaneously. Despite assigning tight tolerances to sub-component manufacture, part variation propagation necessitates expensive and time consuming variation management processes such as shimming in order to ensure the final assembly is …
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Messung des organischen Kohlenstoffgehaltes alpiner Eisproben
… max. 14 ppbC aufwies. Für einen Tiefbohrkern (KCS) des Colle Gnifetti konnte ein systematischer Anstieg des organischen Kohlenstoffgehaltes in den letzten Metern über dem Felsbett nachgewiesen werden. Bei den im vorindustriellen Bereich gefundenen Konzentrationen um 100 ppbC würde somit für …
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The Tumor Suppressor PKCδ Is Critical for UV-Induced G2/M Checkpoint Activation and Apoptosis
… G2/M cell cycle arrest in both primary human KCs and immortalized HaCaT cells. Consistent with a G2/M arrest, PKCδ-cat induced phosphorylation of Cdk1 (Tyr15), a critical event in the G2/M checkpoint. Treatment with the ATM/ATR inhibitor caffeine was unable to prevent PKCδ-cat induced G2/M …
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Exploración de la función hipofisaria en relación con el crecimiento
… determinar simultáneamente los 17 OHCS y los 17 KCS se ha puesto en evidencia, una cierta tendencia a cifras basales bajas de 17 hidroxicorticoides tanto en los nanismos hipopituitarios como en los que no lo son. Sin embargo los valores de los 17 cetosteroides están siempre dentro de los límites …