Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 79 for “"Ionophore"”.
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Molecular Recognition in Host-Guest Ionophore-Siderophore Assemblies
… dibenzo-18-crown-6 macrocycles, and the linear ionophore lasalocid with cationic guests, including substituted protonated amines and the iron siderophore ferrioxamine B is presented. Methodology was developed using ESI-MS to successfully quantitate host-guest interactions in binary and complex …
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Synthese makrocyclischer Thioharnstoff-Ionophore zur katalytischen Darstellung von Tetrametaphosphat und selektiven Nitratkomplexierung bzw. -transport
Mit der Natur als Inspirationsquelle sollte die Funktionsweise der ATP-Synthase durch einen artifiziellen molekularen Assembler vereinfacht nachgeahmt werden – insbesondere der energiespeichernde Prozess der ATP-Synthese. Infolgedessen wurde ein aus vier Thioharnstoffgruppen aufgebauter und über …
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Functional characterization of equine neutrophils in response to calcium ionophore A23187 and phorbol myristate acetate
… ex vivo following stimulation with calcium ionophore A23187 (A23187) and phorbol myristate acetate (PMA). These stimulants trigger different branches of the PMN activation process that occurs in vivo. Equine PMN were isolated from the whole blood of six clinically normal geldings using a …
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Modeling Ionophore Selectivity in the Gas Phase: IR Spectroscopy of Solvated Metal Ion-Crown Ether Complexes
… a variety of biological and naturally-occurring ionophores. Thus, crown ethers have become the prototypical ionophore-model systems in chemistry and biology. Insight gained by studying the interaction of crown ethers with metal ions may lead to the design and development of new ionophores that …
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Sorption Characteristics of Veterinary Ionophore Antibiotics Monensin and Lasalocid and Soil Clay Constituents Kaolinite, Illite and Montmorillonite
<p>Monensin and Lasalocid are veterinary ionophore antibiotics used for therapeutic and non-therapeutic treatment of livestock. Manure containing un-metabolized compounds is in turn used as beneficial amendment for agricultural crops, thus, these compounds may be available for transport through …
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The Development of Ionophore-Selective Based optical chemical sensors for the determination of heavy metal ions in aqueous environments
… has a potential for the use as selective-ionophore for the development of a Pb2+ selective sensing system.
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Mechanisms of Ionophore Toxicoses: Laidlomycin Propionate Toxicosis in the Horse and Monensin, Laidlomycin, and Laidlomycin Propionate in Muscle Cultures
… of E-63 rat skeletal muscle cells. Each of these ionophores induced dose-dependent increases in lactate concentrations, decreases in pyruvate concentrations, and decreases in accumulations of NR. Cultures of both myoblasts and myotubes responded similarly, except that myoblasts had greater lactate …
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Effect of monensin supplementation on ruminal and postruminal digestion in sheep and on adaptation of ruminal microbes
… were conducted to examine the effects of an ionophore, monensin sodium, on digestion in sheep. The first experiment was concerning alterations induced by long-term supplementation and subsequent withdrawal of the ionophore. The diet was a pelleted mixture of 43% native prairie hay, 34% corn …
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Intracellular Calcium and Protein Kinase C Regulate Nonspecific Cell-Mediated Cytotoxicity by Mouse Lymphocytes (Calmodulin)
… of various pharmacological agents. The calcium ionophore A23187 caused a marked increase in nonspecific cytotoxicity by mouse spleen lymphocytes against SV3T3 target cells. Using a standard ('51)Cr-release assay, little target cell death was seen prior to 16 hours of effector-target incubation. …
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Nuclear magnetic resonance studies on phospholipid membranes using paramagnetic ions
… how 1H-nmr and 3 1P-nmr can be used to monitor ionophore mediated transport of lanthanide ions across sonicated vesicular membranes. The metal ion-ionophore stoichiometries and the activation energies of transport were measured. The transport of the charged ion-ionophore complexes into the …
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Multi-Nuclear NMR Studies of Phospholipid Membranes and their Interaction with Membrane Active Substances
… across lipid vesicles in the presence of the ionophores alamethicin, melittin and nystatin was monitored using the lanthanide probe ion Pr3+. Channel characteristics were found to be dependent upon molecular interactions between the lipid and the individual ionophores. The results were …
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Hydrogels containing linear and cyclic polyethers
… The results indicated that the presence of an ionophore can be used to modulate ion transport and that ion transport is described by a dual-sorption mechanism. However, these studies were limited due to ionophore loss during hydration. Hence, the synthesis of a range of acrylate based crown …
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Metabolic alterations to sudden introduction of high carbohydrate diets in ruminating dairy bull calves
… The latter diet was supplemented with either ionophore, buffer or contained no supplementation. Sudden introduction of the diets resulted in transient lactic acidosis. Buffer was more efficient in the prevention of acidosis than ionophore. The acetate : propionate (Ac:Pr) ratio tended to be …
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Granzyme B- und Perforin-positive Lymphozyten in der bronchoalveolären Lavage und dem perpheren Blut bei Patienten mit Asthma bronchiale
… Kultivierung oder Stimulation mit PMA und Ca-Ionophore bzw mit anti-CD3 bestimmt.
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Partial isolation and characterization of the mouse calmodulin genes
… the transfected cells were treated with calcium ionophore to determine if the calcium levels would have an effect. Overexpression of calmodulin did not lead to apoptosis, and the calcium ionophore caused death of the control- and calmodulin-transfected cells.
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Effects of feeding lasalocid and monensin upon mineral status of steers, and partial absorption and renal handling of minerals in sheep
… and the effects of dietary K upon the actions of ionophores. Two 84-d grazing trials were conducted with steers fed no ionophore, 200 mg lasalocid, or 150 mg monensin. Monensin tended to increase gain of steers, but lasalocid had no effect. Feeding supplemental lasalocid and monensin altered Ca, …
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Modeling the hydrolyzing action of secretory phospholipase A2 with ordinary differential equations and Monte Carlo Methods
… use models to determine the ability of calcium ionophore to increased membrane susceptibility.
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Mechanisms by Which Apoptotic Membranes Become Susceptible to Secretory Phospholipase A2
… a simplified model of apoptosis using a calcium ionophore was first applied. Kinetic and flow cytometry experiments provided key observations regarding ionophore treatment: initial hydrolysis rate was elevated, total reaction product was increased four-fold, and adsorption of the enzyme to the …
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Calcium: some aspects of subcellular accumulation and distribution in milk
… as preincubation of vesicles with calcium ionophore resulted in less than 10% of the accumulation found without ionophore. The ATPase inhibitor sodium orthovanadate, and the ATP analog AMP-PNP, reduced ⁴⁵Ca accumulation in all fractions. Protonophore caused a small reduction in ⁴⁵Ca …
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Genomic analysis in human solid tumours:Copper Homeostasis Genes in Colorectal cancer
… copper binding compounds, in particular, the ionophore copper-ionophore 5-chloro-8-hydroxyquinoline (ClHQ) and the copper chelator (N,N,N'N',-tetrakis (2- pyridylmethyl)ethylenediamine (TPEN) in two human colorectal cancer cell lines (Caco-2 and HT29). Moreover, the Atox1 silencing has …
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