Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Insulin growth factor"”.
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Obesity Induced Colorectal Cancer
… a mathematical model that relates obesity and insulin and captures the impact of increasing levels of insulin on the insulin growth factor -1 (IGF-1) pathway. The model is able to predict a risk of colorectal cancer based on a given insulin level.
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Mechanisms of Induction and Maintenance of Constitutive Ptgs2 Expression in Colonic Mesenchymal Stem Cells
… adult colonic epithelium ideally positions this growth factor to affect Ptgs2 expression in vivo. We also found that loss of insulin growth factor 2 binding protein 1: Igf2bp1 or Imp1) results in a decrease in Ptgs2 and confirmed the ability of Imp1 protein and Ptgs2 mRNA to interact in the …
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Prevalence of Low-Energy Availabilty Amongst Female Paralympic Athletes
… were within normal range for all participants. Insulin-growth factor (IGF-1) was elevated ( > 13.1-39.2 nmol/L) in 22% of athletes. Five participants (56%) had clinically low BMD in the hip regional score ( < -2 z-score), one of which reported a bone-related injury within the past year. Based on …
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Comparison on metabolic markers and hormone level according to serum 25-hydroxyvitamin D level
… and white blood cell counts were measured. Insulin like growth factor-I, insulin like growth factor binding protein 3, and sex hormone binding globulin level were measured. We divide the subjects into noraml vitamin D group and vitamin D deficiency group by serum 25-hydroxyvitamin level 20 …
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Recapitulation of Human Placental Insufficiency in a Novel Mouse Model :New Paradigm in Translational Research
… ligation (MUAL) reliably resulting in fetal growth restriction (FGR).Methods: At 18 days, timed mated C57BL/6J dams were divided into two groups: MUAL(n=18) ; and control-sham operated (n=18) with uterine horn fetal positions matched to each MUAL fetus. Pups were delivered on day 20, …
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Development of Protein Based PCBP2 siRNA Nanocomplex for Liver Fibrosis Therapy
… treat liver fibrosis. Cholesterol and IGF2R (insulin growth factor 2 receptor) specific peptide were used as targeting ligands to deliver the siRNA to HSCs. In Chapter 1, we briefly introduced the background about RNA interference (RNAi), liver fibrogenesis, markers of liver fibrosis, and the …
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Intracellular signalling by arachidonic acid metabolites
… serum (0.5% w/v) and albumin, not serumderived growth factors (insulin growth factor (IGF)-1, IGF-2 or epidermal growth factor (EGF), was determined as the key survival factor. Since 15d-PGJ2 is reported to activate peroxisome proliferator activated receptor (PPAR)-γ, the activities of PPARs …
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Longitudinal gene networks, canonical pathways and functional analysis of microarray data from Longissimus thoracis et lumborum muscle samples of early-weaned Angus steers
… with direct and indirect connection to YY1 gene, Insulin Growth Factor Binding Protein 5 (IGFBP5), Signal transducer and activator of transcription 5B (STAT5B), General Transcription Factor 2B (GTF2B), and K(lysine) acetyltransferase 2B (KAT2B), were the genes which showed to have a role on …