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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 20 of 557 for “"IgG"”.

  1. Interrogation and Manipulation of the IGG FC Glycan

    … a constant region, the immunoglobulin G (IgG) Fc protein backbone and conserved N-linked glycan combine to introduce structural diversity in IgG molecules that in turn, triggers divergent humoral responses. These N-glycans are variably constructed, ultimately leading to families of highly …

    rockefeller Repository record for Interrogation and Manipulation of the IGG FC Glycan (opens in a new tab)

  2. Investigating the role of IgG and Fcγ receptors in intestinal inflammation

    … receptors that mediate immune cell activation by IgG, influences susceptibility to inflammatory bowel disease (IBD), suggesting that IgG may be important during gut inflammation. IBD is a chronic relapsing condition with two major subtypes, Crohn’s disease (CD) and ulcerative colitis (UC), both …

    cambridge Repository record for Investigating the role of IgG and Fcγ receptors in intestinal inflammation (opens in a new tab)

  3. Aerosol delivery of Rhodoccocus equi IgG to the lungs of ponies

    … of this study was to determine if R. equi IgG purified from commmercially available hyperimmune R. equi plasma and delivered to the lungs of adult ponies would cause a local inflammatory response and if increases in total and R. equi specific IgG occurred post administration. IgG was …

    vt Repository record for Aerosol delivery of Rhodoccocus equi IgG to the lungs of ponies (opens in a new tab)

  4. Seroprevalence of anti-toxoplasma IgG antibody in HIV patients with neurological manifestations

    … to determine seroprevalence of anti-toxoplasma IgG Ab in HIV/AIDS patient with neurological manifestations, and to establish a rational means for the clinician facing decision making concerning empiric anti-toxoplasma therapy. The Study was conducted between November 2008 and January 2009 at the …

    zambia Repository record for Seroprevalence of anti-toxoplasma IgG antibody in HIV patients with neurological manifestations (opens in a new tab)

  5. Aggregation of IgG mAb Biotherapeutics: Sources, Methods of Characterization, and Biological Implications

    … this Ph.D. thesis research work, three different IgG monoclonal antibodies (2 IgG1 mAbs, one in solution and one in lyophilized form and one IgG2 mAb in solution) were stressed by a variety of different conditions and the resulting aggregates and particles were characterized using a broad array of …

    ku Repository record for Aggregation of IgG mAb Biotherapeutics: Sources, Methods of Characterization, and Biological Implications (opens in a new tab)

  6. Antigen binding properties of IgG and IgM antibody to bovine serum albumin

    This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).

    iupui Repository record for Antigen binding properties of IgG and IgM antibody to bovine serum albumin (opens in a new tab)

  7. Properties of the products of proteolytic cleavage of bovine colostral immunoglobulin G (igG ).

    Dept. of Biological Sciences. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1974 .F24. Source: Masters Abstracts International, Volume: 40-07, page: . Thesis (M.Sc.)--University of Windsor (Canada), 1975.

    windsor Repository record for Properties of the products of proteolytic cleavage of bovine colostral immunoglobulin G (igG ). (opens in a new tab)

  8. "Chasing a ghost": Addressing the opalescence/aggregation relationship of an IgG 1 antibody

    … the aggregation/opalescence relationship of an IgG 1 therapeutic antibody under a variety of conditions. The opalescence characteristics of three antibodies, Mab 1, 2 and 3, were examined as a function of salt dependence, protein concentration and temperature, using a variety of biophysical …

    unh-thes Repository record for "Chasing a ghost": Addressing the opalescence/aggregation relationship of an IgG 1 antibody (opens in a new tab)

  9. Untersuchungen zur differenzialdiagnostischen Bedeutung des IgG-Index und Albuminquotienten bei neurologisch erkrankten Hunden

    Investigation of IgG index and albumin quotient for the differential diagnosis of dogs with neurological diseases In the present study the benefit of IgG index and albumin quotient for the differential diagnosis in dogs with neurological diseases was investigated. The question whether the …

    lmu-germany Repository record for Untersuchungen zur differenzialdiagnostischen Bedeutung des IgG-Index und Albuminquotienten bei neurologisch erkrankten Hunden (opens in a new tab)

  10. Production and Characterization of an Human Monoclonal Antibody IgG to TRAIL Receptor 2

    … vivo 실험에서 보다 더 효과적이며 안정적인 치료용 항체로 만들기 위해 Fab 를 IgG 형태로 바꾸었다. 이는 antibody engineering을 통하여 DR5-18 IgG construct를 제작하는 방법으로 수행되었으며, 포유 세포에 넣어 항체 발현을 할 수 있도록 만들어졌다. 본 학위논문 연구에서는 발현된 DR5-18 IgG를 배양액으로부터 AKTA prime plus 와 HitrapTM IMAC column을 이용하여 정제하였으며 western blotting을 통해 확인하였다. MTT assay, …

    ajou Repository record for Production and Characterization of an Human Monoclonal Antibody IgG to TRAIL Receptor 2 (opens in a new tab)

  11. 동물 세포의 세포질에서 발현된 IgG 의 중쇄와 경쇄간의 조합 여부 및 항원결합 활성 분석

    … 문제가 제기된다. 현재까지 세포질에 면역글로불린 G (immunoglobulin G, IgG) 항체가 발현되었을 때, 항체의 구조 및 항원 결합능력 유지 여부가 자세하게 연구된 것이 없다. 따라서 본 연구에서는 키메릭 3D8 IgG1 (chimeric 3D8 IgG1, ch 3D8 IgG1) 발현벡터를 세포질에 발현시켜 중쇄와 경쇄간의 결합 및 항원 결합능력을 조사하였다. 세포질에서 발현되도록 선도 서열 (leader sequence)을 제거하여 중쇄와 경쇄를 동시에 발현하는 벡터를 제조하였다. ch 3D8 IgG1의 기본구조 …

    ajou Repository record for 동물 세포의 세포질에서 발현된 IgG 의 중쇄와 경쇄간의 조합 여부 및 항원결합 활성 분석 (opens in a new tab)

  12. Serum Specific IgG to Cytokeratin : A Useful Serologic Marker for Toluene Diisocyanate-Induced Asthma

    PURPOSE: Although specific IgE and IgG to isocyanate-HSA conjugate has been used to predict specific bronchoprovocation test results, they are not sensitive enough for the diagnosis of patients with toluene diisocyanate (TDI)-induced asthma. We evaluate the clinical significance of specific IgG to …

    ajou Repository record for Serum Specific IgG to Cytokeratin : A Useful Serologic Marker for Toluene Diisocyanate-Induced Asthma (opens in a new tab)

  13. Designing Immune-Instructive Biomaterials: The Interplay of Biomaterial surface, IgG Unfolding, and Macrophage Modulation

    This doctoral research investigates how biomaterials can be designed to guide the immune system’s response in beneficial ways. By studying how the immune system interacts with different model implant materials, the work reveals strategies to modulate immune response, promote healing and improve the …

    adelaide Repository record for Designing Immune-Instructive Biomaterials: The Interplay of Biomaterial surface, IgG Unfolding, and Macrophage Modulation (opens in a new tab)

  14. Purification and quantitative description of Rhodococcus equi IgG designed for aerosol nebulization to foals

    The objective of this study was to purify IgG from commercially available hyperimmune Rhodococcus equi plasma and to assess the delivery of IgG as an aerosol to the equine lung. IgG was purified from plasma, and the IgG concentration of both the plasma and the purified IgG was determined by ELISA. …

    vt Repository record for Purification and quantitative description of Rhodococcus equi IgG designed for aerosol nebulization to foals (opens in a new tab)

  15. Infección por virus sincitial respiratorio y su relación con valores de IGG en niños críticos

    … de acuerdo a la categorización de las prueba de IgG. Resultados: De 188 pacientes que ingresaron a la UCIP, 13% presentaron infección por VSR (24), con una edad promedio de 7,3 (DE=3,6) meses. Pertenecían al sexo masculino79,83%. Se encontró que 12,5% tenían un valor de IgGbajo para su edad, …

    rosario Repository record for Infección por virus sincitial respiratorio y su relación con valores de IGG en niños críticos (opens in a new tab)

  16. Investigating the novel interaction between hERG and the Fc region of IgG and its consequences

    … (HEK) cells. In addition to anti-Ro52, several IgG antibodies were found to interact with hERG and induce chronic channel internalization, reducing hERG current (IhERG) by 23-56%, with the Fc region in particular identified to solely convey these effects through binding to the S5-pore linker. …

    queens Repository record for Investigating the novel interaction between hERG and the Fc region of IgG and its consequences (opens in a new tab)

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