Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"IGRT"”.
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Development and Realization of the IGRT Inline Concept
A new concept for the integration of an imaging system into a medical linear accelerator for radiotherapy is presented, and its technical realization is described. An x-ray tube and a flat panel detector were installed along the treatment beam axis, such that the detector could not only be used for …
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Effects of Advanced Radiotherapy techniques on Normal Tissue Toxicity in Breast Cancer
… New radiotherapy techniques including IMRT and IGRT have the potential to reduce late treatment related toxicities. The aim of this thesis was to investigate if the use of IGRT and IMRT can reduce the breast tissue related late complications after whole breast radiotherapy. The project evaluated …
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Volumetric, Magnetic Resonance-Visible, and Radiation-Sensitive Detectors For Magnetic Resonance Image-Guided Radiation Therapy
… advent of MR image-guided radiation therapy (MR-IGRT) using systems, such as the 1.5 MRI – 7 MV linear accelerator (MR-Linac), now allow for improved soft-tissue on-board imaging for patient position and tumor target localization verification and the ability to assess functional biological tissue …
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Polymer Gel Dosimetry in Magnetic Resonance-Image Guided Radiation Therapy
… adaptive radiotherapy guided by MR imaging (MR-IGRT) and has been proposed as an advanced radiotherapy treatment modality. The delineation of the tumor and adjacent organs is greatly improved by the soft tissue contrast available from MR images. With novel integrated devices, MR images can be …
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An Implantable Mosfet Dosimeter Modified to Act As A Fiducial Marker
… marker for image guided radiation therapy (IGRT) treatment if it could be modified to be visible on x-rays. In this study, modifications to the MOSFET dosimeter were made to increase its visibility for IGRT treatment. To test whether the modifications hindered the dosimeter’s ability to …
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Clinical symptoms and volumetric radiological responses of acoustic neuroma patients, treated with hypo-fractionated image guided radiotherapy (IGRT) at Groote Schuur hospital between 2013 and 2016
Background: Stereotactic radiosurgery (SRS) is the gold standard for treatment of small and medium sized tumours, although fractionated regimens are well described. Access is limited in resource-constrained settings. There are no South African data describing outcomes of AN patients treated with …
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Modelling geometric uncertainties in prostate radiotherapy
Image guided radiotherapy (IGRT) presents a range of techniques to enhance thegeometric accuracy of radiotherapy treatment. A full evaluation of such techniques,against increased cost, workload, or unnecessary radiation dose, would require theincorporation of geometric errors into existing methods …
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Evaluation of Deformable Image Registration For Improved 4D Ct-Derived Ventilation For Image Guided Radiotherapy
… avoidance. This image-guided radiotherapy (IGRT) strategy may reduce the injury and/or functional loss following thoracic radiotherapy. 4D computed tomography (CT), developed for radiotherapy treatment planning, is a relatively new imaging technique that allows the acquisition of a …
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Η θέσης της ακτινοθεραπείας στα σύγχρονα πρωτόκολλα νεοεπικουρικής θεραπείας για αδενοκαρκίνωμα της γαστροοισοφαγικής συμβολής
… σύγχρονες τεχνικές ακτινοθεραπείας (IMRT, VMAT, IGRT) και οι στρατηγικές διαχείρισης οξείας και όψιμης τοξικότητας, με ιδιαίτερη έμφαση στην ανάγκη τυποποίησης διαδικασιών και πολυεπιστημονικής προσέγγισης. Επιπρόσθετα, η ανασκόπηση εντάσσει τα δεδομένα των τριών πιο σύγχρονων τυχαιοποιημένων …
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Optimizing Kilovoltage Cone-Beam Computed Tomography for Image-Guided Radiation Therapy
… applications in image guided radiation therapy (IGRT). In its current state, CBCT is suboptimal for these applications due to its considerable radiation dose, poor soft-tissue contrast and inaccurate Hounsfield Units as a result of in-patient scatter. The specific aims of this dissertation …
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Applications of cone beam computed tomography in radiotherapy treatment planning.
In recent years Image-Guided Radiotherapy (IGRT) has experienced many technical advances. One of the most significant has been the widespread implementation of kilovoltage imagers attached to the gantry of linear accelerators (LINACs); these units are capable of 2D planar imaging, fluoroscopy and …
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Development of Five-dimensional Magnetic Resonance Imaging (5D-MRI) for Radiation Therapy
<p>Accurate delineation of tumor target and organs at risk (OARs) is critically important in modern radiation therapy for optimal treatment planning and precise treatment delivery. Conventionally, radiotherapy treatment planning uses 2D X-ray or 3D CT images to assist the delineation of tumor …
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Risk stratification in the management of localised prostate cancer treated with radical radiotherapy
The National Cancer Institute defines precision medicine as ‘a form of medicine that uses information about a person’s genes, proteins, and environment to prevent, diagnose, and treat disease’. When applied to radiation oncology, it may be considered from two separate but interlinked perspectives; …
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Forecasting Longitudinal Changes In Oropharyngeal Tumor Volume, Position, and Morphology During Image-Guided Radiation Therapy
<p>The purpose of this work was to generate, evaluate, and compare models that predict longitudinal changes in oropharyngeal tumor volume, position, and morphology during radiation therapy.</p> <p>One volume, one position, and two morphology (size, shape, and position) feature vectors were used to …
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Design and Optimization of Four-Dimensional Cone-Beam Computed to mography In Image-Guided Radiation Therapy
<p>The influence of respiratory motion on patient anatomy poses a challenge to accurate radiation therapy, especially in lung cancer treatment. Modern radiation therapy planning uses models of tumor respiratory motion to account for target motion in targeting. The tumor motion model can be verified …