Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 29 for “"Hypoxemia"”.
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Effects of Long-Term, High-Altitude Hypoxemia on Fetal Ovine Coronary Arteries
… the effects of long-term, high-altitude hypoxemia on the contractility of fetal coronary vessels, namely the left circumflex, left anterior descending, and right coronary arteries. We have found that in response to chronic hypoxia, isolated fetal ovine coronary arteries exhibit attenuated …
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Effects of emphysema and chronic hypoxemia on skeletal muscle oxygen supply and demand
… conducted to test the hypothesis that chronic hypoxemia leads to alterations in oxygen transport and muscle function. A primary objective was to validate elastase-induced emphysema in rats as an animal model of skeletal muscle dysfunction in COPD.Arterial blood gases were used to determine the …
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Validation of tissue oxygen saturation determined by near-infrared spectroscopy in canine models of hypoxemia and hemorrhagic shock
The objective of this study was to evaluate the relationship between tissue oxygen saturation (StO2) and oxygen delivery index (DO2I). Oxygen delivery index is product of two factors arterial oxygen content (CaO2) and cardiac index (CI). In this study the relationship between DO2I and StO2 was …
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Effect of Long-Term Hypoxia on Myocardial Alpha1- Receptors
… the effect of long-term high-altitude hypoxemia on the α<sub>1</sub>- and β<sub>1</sub>-adrenergic receptor interaction in the heart. The interactions between two receptor systems were examined by prior stimulation of muscles with α<sub>1</sub>-adrenergic agonist phenylephrine (PHE). …
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An exploratory study of neuropsychological impairment, driving performance, and sleepiness in obstructive sleep apnoea and chronic obstructive pulmonary disease
… arousals during sleep, and/or the degree of hypoxemia and oxygen desaturation. In contrast, the level of impairment seen in COPD is related to the degree of hypoxemia both during sleep and during waking hours. The major aim of this study was to compare driving performance and …
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Brain Injury and Inflammation and Placental Inflammation in Response to Repetitive Umbilical Cord Occlusions in the Near Term Ovine Fetus
… injury, which will be exacerbated by chronic hypoxemia and low-grade infection. Chronically instrumented fetal sheep served as controls or underwent repetitive UCOs for up to 4 hours or until fetal arterial pH was2saturation pre-UCOs of >55% and
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ΜΕΛΕΤΗ ΤΩΝ ΣΧΕΣΕΩΝ ΑΕΡΙΣΜΟΥ/ΑΙΜΑΤΩΣΗΣ (VA/Q), ΤΟΥ ΠΝΕΥΜΟΝΑ ΜΕΤΕΓΧΕΙΡΗΤΙΚΑ ΚΑΙ ΟΙ ΜΕΤΑΒΟΛΕΣ ΤΟΥΣ ΑΠΟ ΤΗΝ ΚΑΘΙΣΤΙΚΗ ΘΕΣΗ
… THAT POST-OPERATIVE PULMONARY DYSFUNCTION AND HYPOXEMIA IS MAINLY CAUSED BY A SHUNT LIKE EFFECT.SITTING POSITION IMPROVES PULMONARY GAS EXCHANGE IN PATIENTS WITH VA/Q INEQUALITIES. SITTING POSITION DOES NOT REDUCE THE TRUE INTRA PULMONARY SHUNT BUT INCREASES ALVEOLAR VENTILATION THUS DECREASING …
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Evaluation of clinical methods of pulmonary gas exchange assessment in the standing horse
… Albuterol caused significant (p<0.05) hypoxemia 15 minutes following inhaled administration. This was accompanied by a significant increase in Q<sub>S</sub>/Q<sub>T</sub>, suggesting that the hypoxemia was due to increases in which the ratios of ventilation to perfusion were decreased.
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Tierexperimentelle Untersuchungen zu Praktikabilität und Hämokompatibilität einer miniaturisierten extrakorporalen Membranoxygenierung
… ventilation strategy is necessary to prevent hypoxemia but causes further damage to the lungs. The ventilator-induced lung injury leads to irreversible lung damage and increases mortality. With extracorporeal membrane oxygenation using capillary membrane oxygenators specialized centers have …
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A norm- and control-referenced comparative study of the neuropsychological profiles of shift workers and patients with obstructive sleep apnoea (OSA)
… The possibility arises that intermittent hypoxemia and sleep deprivation due to sleep fragmentation in OSA and sleep deprivation secondary to sleep cycle disruption in shift work may underlie neuropsychological deficits, which in turn meditate these functional impairments. The current …
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Effects of hypervolemia on arterial oxygenation in thoroughbred horses performing exercise simulating the second day of a 3-day equestrian event
… Leon et al. 2002). Exercise induced arterial hypoxemia is not typically seen during moderate exercise in normal horses and hyperhydration (and hypervolemia) does not affect arterial oxygen tension or hemoglobin saturation during short term maximal exertion (Manohar et al. 2003). Studies were …
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Partielle Resistenz Chorea Huntington transgener Mäuse gegen globale cerebrale Ischämie
… which then induce a tolerance against a second hypoxemia. In our model, ischemic tolerance was not blocked by pre-treatment of mice with cycloheximide, an unspecific protein synthesis inhibitor. We therefore conclude that there must be a different mechanism - independent of the short term …
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Totale antioxidative Kapazität bei am Herzen operierten Kindern
… 100% O2 during CPB was investigated. The role of hypoxemia was investigated. The influence of ischemia-reperfusion injury and oxidative stress on clinical outcome was studied. 26 children (aged from 6 to 180 months) with cyanotic (n=6; Fallot) or non cyanotic cardiac defect (n=20; VSD, ASD, AV) …
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Effekte von Iloprost auf Hämodynamik und Gasaustausch beim akuten Lungenversagen : eine tierexperimentelle Studie
… ventilation and perfusion, resulting in grave hypoxemia, pulmonary hypertension, high pulmonary right-to-left shunt and complex inflammatory events. In spite of modern proposals of therapy, it leads to a lethal disease pattern in many cases. Vasodilatores, especially their inhalational form of …
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Neuropsychological Sequelae of Obstructive Sleep Apnea in Later Adulthood
… indicated executive functions were related to hypoxemia and sustained attention was related to sleep fragmentation in the current study. A medical sequelae model and a neuropsychological sequelae model were tested. The neuropsychological sequelae model predicted whether one was a control or an …
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Canine cardiopulmonary responses to one-lung ventilation during thoracoscopic diaphragmatic incision repair and two-lung ventilation during gasless laparoscopic diaphragmatic incision repair
… may predispose to an increased risk of hypoxemia when compared to left lung collapse with right lung ventilation;(2) Two video-assisted surgical techniques are described for the repair of diaphragmatic incisions: (a) gasless laparoscopy with an abdominal lifting device and (b) …
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Tissue enzyme changes in air-exposed American eels.
… that the eel suffers from acidosis and hypoxemia as a result of this air exposure, but the survival of the eels despite these conditions demonstrates a large degree of tolerance to these effects. This thesis will investigate the changes in tissue enzymes of the American eel as a result …
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Targeting Endothelial Pathological Calcium Signaling Accelerates Resolution of SARS-CoV-2-Induced ARDS
… alveolar damage, pulmonary edema, and severe hypoxemia, with limited therapeutic options. Increasing evidence identifies endothelial dysfunction and vascular barrier disruption as central drivers of ARDS pathogenesis, particularly in the context of SARS-CoV-2 infection. This thesis …
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Serum calcitonin gene-related peptide concentrations in the horse and their relationship to the Systemic Inflammatory response
… fungal or parasitic invasion or from trauma or hypoxemia. Local and systemic release of a wide variety of endogenous pro-inflammatory mediators results in activation of the innate immune system in order to resolve the insult. In sepsis this initial appropriate host response becomes amplified and …
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Verlauf der PCT-Blutkonzentrationen während und nach Herzoperationen mit extrakorporaler Zirkulation bei Kindern
… We divided these patients into patients with hypoxemia along with Fallot’ sche tetralogy and patients with cardiac insufficiency caused either by VSD or AVSD. Both groups showed a comparable average age and showed no significant difference in the duration of the EKK, arterial cuff closure and …
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