Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 18 of 18 for “"Hyperparathyroidism"”.
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Induced hyperparathyroidism in the rat
Thesis (M.S.)--Michigan State University of Agriculture and Applied Science. Dept. of Physiology and Pharmacology, 1959
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A population based study of primary hyperparathyroidism in Tayside, Scotland
Background: Primary hyperparathyroidism (PHPT) is a common endocrine disorder with increasing prevalence, but the majority of cases (over 85%) are now perceived to be mild and remain untreated. Objectives: The main focus of this thesis is to provide an accurate update of the epidemiology of PHPT …
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Characterizing the Development of Secondary Hyperparathyroidism and Vitamin D Resistance in Experimental Chronic Kidney Disease
… mainstay therapy for the treatment of secondary hyperparathyroidism (SHPT) that develops in CKD. A major issue with therapy includes the development of calcitriol resistance and increased vascular calcification. Modifications to the PTG that hinder its sensitivity to calcium (Ca) and PO4 are …
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Pre-operative localization and surgical outcomes for primary hyperparathyroidism (PHPT): An 11-year review at a South African hospital
Introduction: Primary Hyperparathyroidism (PHPT) is characterized by hypersecretion of PTH leading to hypercalcaemia with successful surgery being the only definitive cure. Broadly, three techniques of parathyroidectomy exist: open bilateral neck exploration and minimally invasive …
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The effect of continuous infusion of human parathyroid hormone on bone architecture in female mice
… sought to create an animal model of secondary hyperparathyroidism through continuous infusion of parathyroid hormone (PTH) in adult female mice, and to subsequently study the catabolic effects of PTH. Osmotic pumps were implanted subcutaneously and infused either vehicle, 40 pg/kg/day of PTH or …
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Nuclear-Medical Methods for Diagnosing of Abnormal Parathyroid Glands in Primary and Secondary Hyperparathyroidism // Нуклеарно-медицински методи за диагностика на абнормни паращитовидни жлези при първичен и вторичен хиперпаратиреоидизъм
Първичният хиперпаратироидизъм (ПХПТ) се дължи на свръхпродукция на паратироиден хормон (ПТХ) от една или повече абнормно променени паращитовидни жлези и води до развитие на хиперкалциемия. Доскоро считан за рядко заболяване, в последните години с навлизане в клиничната практика на рутинно …
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Changes of parathyroid hormone and vitamin D metabolites according to glomerular filtration rate in chronic kidney disease patients
… are addressed and treated. While secondary hyperparathyroidism develops during the early stages of chronic kidney disease, few patients are evaluated for elevations in serum parathyroid hormone (PTH) before they become frankly hypocalcemic. Quantification of the prevalence of these …
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Mathematical modelling of bone remodelling at the cellular level and the interaction between myeloma cells and the bone microenvironment
… osteoporosis, hypothyroidism and primary hyperparathyroidism. Due to the large number of bone cell types, stages of differentiation, and the numerous growth factors and cell to cell interactions involved, our current understanding of bone remodelling and the coupling between osteoblasts …
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Calcium/Phosphate Regulation: A Control Engineering Approach
… bone mineral density), which arises from primary hyperparathyroidism (PHPT) – hyper secretion of PTH. Existing in silico models of Ca homeostasis in humans are often cast in the form of a single monolithic system of differential equations and are not easily amenable to the sort of tractable …
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The clinical characteristics, complications and treatment outcomes of patients with osteoporosis at Groote Schuur Hospital
… n=77), steroid use (21.6%, n=57) and primary hyperparathyroidism (15.2%, n=40). A fragility fracture was diagnosed in 68.6% (n=181) - vertebral only (54.7%, n=99), hip only (14.9%, n=27), vertebral and hip (10.5%, n=19), wrist (7.2%, n=13) and other (12.7%, n=23). Bisphosphonates were used by …
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Control of Hepatitis B and C virus infection in chronic haemodialysis patients
… B cell proliferation in dialysis patients with hyperparathyroidism. Hepatitis C virus (HCV) infection in haemodialysis patients has been associated with blood transfusions in many studies. However, evidence exists that transmission between patients also occurs. There is disagreement as to what …
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PARATHYROID HORMONE ACTIVITY AND RELATED CLINICOPATHOLOGICAL ALTERATIONS IN DOGS AFFECTED WITH CHRONIC KIDNEY DISEASE
Renal secondary hyperparathyroidism (RHPT) is a common complication in humans and dogs affected with chronic kidney disease (CKD). RHPT is promoted mainly by the loss of nephrons and consequent hyperphosphatemia and its severity increases in parallel to the disease. The identification and …
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Bayesian Hierarchical Models for Data Extrapolation and Analysis in Rare and Pediatric Disease Clinical Trials
… drug cinacalcet in treating pediatric secondary hyperparathyroidism (HPT). The thesis then turns to methods useful in the study of X-linked adrenoleukodystrophy (X-ALD), a rare neurodegenerative disease for which Lorenzo’s Oil (LO) is one of the few available treatments. We offer a hierarchical …
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Uraemic vascular damage and calcification in children with chronic kidney disease
… Dysregulated mineral metabolism, manifested by hyperparathyroidism and high phosphate, in association with low vitamin D levels, is key to the pathophysiology of ectopic vascular and soft tissue calcification. In addition, a number of treatment- related factors can potentially lead to a high …
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Diagnosis and Management of Mineral and Bone Disorders in Patients with Chronic Kidney Disease on Conservative and Dialysis Treatment /// Диагностика и лечение на минералните и костни нарушения при болни с хронични бъбречни заболявания на консервативно и диализно лечение
[Цел на дисертационната разработка е анализ на диагностичните, клинични и терапевтични аспекти на КМН-ХБЗ в хода на консервативното и хемодиализно лечение чрез изследване на диагностичната и прогностична стойност на съвременни биомаркери за развитие на вторичен хиперпаратиреоидизъм и КМН-ХБЗ; …
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Chirurgische Therapie des primären Hyperparathyreoidismus : Untersuchungen zu Effizienz und Sicherheit der offenen minimal invasiven Parathyreoidektomie
Minimal invasive chirurgische Techniken zur Therapie des primären Hyperparathyreoidismus (pHPT) konkurrieren mit dem bisherigen Standardverfahren, der bilateralen zervikalen Exploration, sofern eine lokalisierte Eindrüsenerkrankung vorliegt. Zusätzlich vorhandene, operationspflichtige …
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ΣΥΜΒΟΛΗ ΤΟΥ ΑΚΤΙΝΟΛΟΓΙΚΟΥ ΕΛΕΓΧΟΥ ΣΤΗΝ ΕΚΤΙΜΗΣΗ ΤΗΣ ΝΕΦΡΙΚΗΣ ΟΣΤΕΟΔΥΣΤΡΟΦΙΑΣ
RADIOLOGICAL STUDIES WERE PERFORMED IN 43 HEMODIALYRED PATIENTS. THEY INCLUDED SKELETAL SURVEY AND FINE DETAIL RADIOGRAPHIES (MAMMOGRAPHY TECHNIQUE) OF BOTH HANDS WHICH WERE STUDIED BY MAGNIFICATION FOR EARLIER DETECTION OF MINIMAL BONE RESORPTION. THE SKELETAL SURVEY INCLUDED VIEWS OF THE THORAX, …