Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 82 for “"Human physiology"”.
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Human Physiology and Acheulean Handaxe Design
… understanding the role these tools played in human evolution. Since the 1960’s, experimental archaeology and increasingly sophisticated quantitative analyses have brought us much closer to answering many fundamental questions about their true nature. Nonetheless, uncertainty remains about …
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The role of mitochondrial transporters in human physiology and adverse drug effects
… aim of this thesis is to evaluate the role of human mitochondrial transporters in adverse drug effects, to overcome the technical challenges in their functional characterisation and to identify compounds that can inhibit substrate transport. So far, most drug interactions have been reported for …
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The acute and phase-shifting effects of artificial bright light on human physiology, performance and symptoms of jet-lag
… day has a fundamental role in synchronising human circadian rhythms. Artificial light is known to alter circadian timing depending on time of administration; early morning light can advance circadian timing while late evening light can delay circadian rhythms. Nevertheless, there is a lack of …
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An investigation into the cognitive skills required by pupils to master concept formation in the field of homeostasis, an aspect of human physiology
… in the area of homeostasis, an aspect of human physiology. During this investigation a number of pupils, the pioneer group, were screened for cognitive deficiencies. major cornmon deficiencies were identified as impulsivity, the use two or more sources of information simultaneously, …
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A mathematical model to simulate physiological adjustments to extreme environments to analyse human responses to adverse environmental conditions
Humans are among the most adaptable species on Earth, yet extreme environmental conditions impose significant limits to human performance, wellbeing, and survival. The study of human physiology in extreme environments is challenging due to the ethical and practical constraints of conducting …
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Jimmy Hit His First Home Run
… Hit His First Home Run. Topics discussed include Human Physiology, Transference, Buddhism, and Bubbles. This document was created in Microsoft Word 2004 for Mac, Version 11.2.
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Oxygen toxicity and radiation injury to the pulmonary system / by Geoffrey McLennan.
… peripheral lung and in lung cells. Animal and human studies have been used. Methods include cell culture with function studies, protein chemistry, animal and human physiology, and cell and lung structure through histopathology, and various forms of electron microscopy. The work resulting from …
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Exploring the application of Natural Language Processing to scientific medical cannabis publications
… the key connections between cannabis compounds, human physiology and disease from the existing medical literature. First, natural language processing techniques (such as document clustering and topic modelling, global vector word embeddings and supervised document classifiers) are used to group …
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Large-scale inference and imputation for multi-tissue gene expression
… omics integration promises a system-wide view of human physiology, with potential to shed light on intra- and multi-tissue molecular phenomena, but faces many complexities arising from the intricacies of biomedical data. This integration problem challenges single-tissue and conventional techniques …
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Biomechanical regulation of epigenetics and chromatin organization in single living cells
… various cellular functions that control human development, cancer, disease, and aging. It, however, remains elusive how mechanical cues regulate biochemical mechanisms in the nucleus that control cellular decision-making. These mechanisms include epigenetic modification, chromatin …
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Design and development of a mechatronic training simulator for adult ECMO
… is integrated with a mathematical model of human physiology to simulate real-time patient vitals and training scenarios, and to control the trainer hardware. We present results related to successful cannulation under ultrasound scanning and a simple patient scenario of hypovolemia.
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In vivo steroid sensing using corona phase molecular recognition : design, synthesis, and applications
… of underlying biochemical processes controlling human physiology and disease. Changes in steroid hormone concentration and activity are often either indicators or direct causes of disease. In the clinic, steroids are measured as biomarkers of health and have been studied in relation to various …
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Human embryonic stem cells for genotoxicity testing
… of various agents, often poorly reflect human physiology. Lack of standardization also limits use of primary explanted cells. Human embryonic stem cells (hESCs) have been validated as a stable and healthy human cell source. This study aimed to investigate the utility of hESCs as a …
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The impact of a laptop computer assisted technology option on biology students' choice of a multi-media instructional methodology
… students' improvement in achievement scores in physiology. The aim of this study was to explore the ,impact of the three instructional options, achievement, and preferences, on biology students with respect to gender and choice of instructional programme. The quantitative data was obtained from …
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A big data and online health analytics framework extended to integrate clinical and countermeasure decision support
… Support Systems (CDSS) have proven to impact human lives in applications on Earth and in space. In the application of Space Medicine Decision Support Systems (SMDSS) on ISS missions and future space missions to the Moon and Mars, there is no known methodology that supports the unique …
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Advanced aircraft seat design : designing features for improving comfort and ergonomy
… involved three phases. In the first phase, the human factors research area, which includes ergonomics, human physiology and anthropometry, was studied. Moreover, passenger survey and quality function deployment were implemented. For the second phase of the design project a second passenger …
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Ubiquitin Conjugase UBE2K Is Essential for Normal Rat Development and Spermatogenesis
… models allow us to investigate questions about human physiology using in vivo systems. Following the advent of gene targeting by homologous recombination in mouse pluripotent embryonic stem cells during the early 1980's [Reviewd by (Hamra, 2010)], the laboratory mouse has emerged as the most …
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Development and Application of Chemoenzymatic Tools to Investigate Site-Specific Protein ADP-Ribosylation
… of this widespread protein modification in human physiology and disease.
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Cardiovascular parameter estimation using a computational model
… continuously recording signals produced by the human body. Currently, these signals need to be interpreted by a clinician in order to assess the state of the patient, to formulate physiological hypotheses, and to determine treatment options. With recent technological advances, the volume of …
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Space, light, and time : prospective analysis of Circadian illumination for health-based daylighting with applications to healthcare architecture
… This thesis describes an objective link between human health and architectural design. Specifically, the link between daylight and human circadian rhythm (as a proxy for health) is explored. The purpose of this thesis is increase understanding about the health effects of daylighting in …
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