Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 110 for “"Human pathogens"”.
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Investigating behaviors of zoonotic and human pathogens on plants
… food crops become contaminated with foodborne pathogens as well as how these organisms persist within the phyllosphere and rhizosphere of these plants is an extremely complex issue. In addition, the CDC estimates that unspecified agents are responsible for 38.4 million out of the 48 million (80 …
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Plastics and Microplastics as Vectors for Bacteria and Human Pathogens
… focus on<em> Vibrio spp</em>., including the human pathogens, <em>Vibrio cholerae</em>, <em>Vibrio parahaemolyticus</em>, and <em>Vibrio vulnificus</em>.</p> <p>Colonization experiments were set up in a tributary of the lower Chesapeake Bay to follow <em>Vibrio spp</em>. colonization and total …
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Complement evasion strategies of human pathogens - the evolutionary arms race
… is centrally involved in host defense against pathogens, its overactivation or deregulation may excessively amplify inflammation and contribute to immunopathology. Periodontitis, an oral infection-driven chronic inflammatory disease, has been linked with complement disruption by periodontal …
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Resistance Responses in Pseudomonas aeruginosa PAO1 in Response to Surface Predation by Myxococcus xanthus DK1622
… driving the evolution of bacteria including human pathogens. Virulence factors and antibiotic resistance may have originated as a stress response mechanism for avoiding predators. <em>Myxococcus xanthus</em> is a micropredator for a wide variety of bacteria including clinically relevant human …
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The Biotechnological Applications of an Insect-Specific Alphavirus
… appear to be evolutionarily related to many human pathogens but have either lost or have yet to gain the ability to replicate in vertebrates. The discovery of ISVs has raised many questions as to the origin and evolution of many human pathogenic viruses and points to the role that arthropods …
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TEMPORAL DYNAMICS, ANTIMICROBIAL RESISTANCE AND PHYLOGENETIC RELATIONSHIPS OF BACTERIAL TAXA IN IRRIGATION WATER SOURCES AND RELEVANCE TO FOOD SAFETY
… sources are often contaminated with many known human pathogens such as E. coli, Salmonella and Listeria and unknown/understudied pathogens such as Aeromonas that are associated with foodborne outbreaks. To facilitate the adoption of microbiologically safe irrigation water sources, a …
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Comparing Biology Grades Based on Instructional Delivery and Instructor at a Community College: Face-to-Face Course Versus Online Course.
… gathered from General Biology I, Microbiology of Human Pathogens, Human Anatomy and Physiology I, and Human Anatomy and Physiology II courses.</p> <p>Univariate analysis of variance, linear regression, and descriptive analysis were used to analyze the data and determine which variables …
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Investigating contamination of dental-unit waterline systems and microbial biofilm ecology
… were employed for investigating spread of human pathogens with aerosolization and splatter of DUWL water; retraction valve failure; waterborne biofilm ecology and environment within a simulated laboratory DUWL (sDUWL) and whether amoebae were harboring nosocomial bacteria. Results: The …
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Characterization of Hemocytes in Amblyomma americanum and Investigation of TRAF6’s Role in Proliferation of Hemocytes in Response to Infection
… with the long-term goal of determining how human pathogens evade detection in this vector.</p>
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Proteomics approach on the identification of virulence factors of enteropathogenic and enterohemorrhagic Escherichia coli (EPEC and EHEC) and further characterization of two effectors: EspB and NleI
… coli (EPEC and EHEC) are two closely related human pathogens responsible for food-borne epidemics in many countries. Several virulence factors together with some putative proteins were identified from the extracellular proteomes of EPEC and EHEC. One of the major secreted proteins, EspB, was …
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Investigating pathogen 4Fe-4S protein targets and cancer chemotherapies with bisphosphonate/diphosphate inhibitors
… pathway) pathway in bacterial and parasitic human pathogens and inhibition of isoprenoid synthases in human cancers. For the development of antibacterials and antiparasitics, this research investigates the structure, function, and inhibition of the essential penultimate and ultimate enzymes …
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Relationship of plasmids in Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium scrofulaceum
… scrofulaceum</i> group (MAIS) are opportunistic human pathogens and widespread in the environment. The first objective of this study was to demonstrate that plasmids from clinical isolates are closely related to plasmids from environmental MAIS isolates. A 12.9 kb plasmid, pVT2, from a clinical …
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Structure-Guided Development of Antifungal Protein Farnesyltransferase Inhibitors and DNA Polymerase Engineering
<p>Eukaryotic human pathogens present a serious threat to global health, causing hundreds of millions of infections with high death rate each year. Fungi and protozoa are two major classes of eukaryotic pathogens. Fungi Cryptococcus neoformans, Candida albicans, and protozoa Plasmodium falciparum …
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Human enteroids as a model for infectious disease
The human gastrointestinal (GI) tract is a major site of host-pathogen interactions. As such, many human pathogens have evolved to either use the GI tract as a portal of entry to gain access to distal sites in the body or cause acute disease within the GI tract. For many years we lacked a suitable …
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Novel techniques for the in situ detection of bacteria on salad leaf surfaces
… both indigenous leaf bacteria and viable human pathogens on salad leaves, without the need for recovery and culture, which may reduce the accuracy of quantification. The methods developed could then be used to quantify the number of indigenous and inoculated bacteria in situ on salad …
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A TOLL-LIKE RECEPTOR-INDUCIBLE AND B CELL-SPECIFIC ENHANCER REGULATES MURINE GAMMAHERPESVIRUS 68 LATENCY AND REACTIVATION
… pathogen of rodents and is related to the human pathogens Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV). MHV68, EBV, and KSHV are lymphotropic and are associated with a variety of lymphadenopathies, carcinomas, and lymphomas. B cells are the main latent …
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Mycobacterium Tuberculosis Virulence Factor Mpt64 Targets the Endoplasmic Reticulum
… of tuberculosis, is one of the most successful human pathogens. One reason for its success is that M. tuberculosis can reside within host macrophages, a cell type that normally functions to phagocytose and destroy infectious bacteria. However, M. tuberculosis is able to evade macrophage defenses …
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A retrospective study to evaluate the efficacy of trimethoprim/sulfamethoxazole (TMP/SMX) compared to daptomycin or linezolid for the treatment of infections due to methicillin-resistant <i>staphylococcus aureus</i> (MRSA)
… is still considered one of the most significant human pathogens in terms of morbidity, mortality, and costs. Vancomycin should be avoided if possible for the treatment of MRSA when the Minimum Inhibiting Concentration (MIC) to Vancomycin is 2μg/mL, as it poses a therapeutic challenge. Main …
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Functional Characterisation of the Mycobacterial Virulence Protein Erp
… of tuberculosis, is among the most successful human pathogens. Throughout their complex life cycle in the host – infection, growth, transmission – mycobacteria must continually resist host defences. A major mycobacterial survival mechanism lies in the unusual and complex cell envelope. The …
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The Use of Spectroscopic Techniques in the Characterization of Mycobacterial Metabolites
… pathogenesis and virulence of different serious human pathogens including <em>Mycobacterium tuberculosis</em> the causative agent of tuberculosis (TB). In the genomic era, it is crucial to develop new methodologies to analyze these components from a global perspective in a comprehensive and …
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