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Showing 1 to 6 of 6 for “"Hofbauer cells"”.
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Phenotypic and Functional Characterisation of Hofbauer Cells Across Gestation
… immature capillaries and macrophages, termed Hofbauer cells (HBC). HBC are the only fetal immune cell population found in the healthy placenta throughout pregnancy. The roles of HBC at different stages of pregnancy are unclear, but they are likely to be important in placental development. We …
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Characteristics of decidual macrophages and Hofbauer cells in placentas of HIV positive women on antiretroviral therapy
Macrophages are the most abundant immune cells at the maternal-foetal interface of term placentas. They play a role in regulating pregnancy, promoting immunological tolerance, and maintaining a homeostatic environment crucial for foetal development. Numerous studies have reported the dysregulation …
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Ανοσοϊστοχημική μελέτη του πλακούντα με ιδιαίτερη έμφαση στα κύτταρα Hofbauer
… We studied the reaction of the trophoblast and Hofbauer cells to nineteen antigens. 2. Comparative study between the three trimester of gestation is reported for the first time. 3. The study for the antigens CALLA, Macrophages-Dako, K-67, Leu-M5, IL-2R, T4, Leu-3a+3b and S-100 in placenta is …
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Adaptation to environmental stress in the human placenta
… placental specific pro-angiogenic macrophages, Hofbauer cells, contributing to increased capillary growth seen among Andeans residing at high altitude. Among the altitude-associated differentially expressed genes, we saw decreased expression of genes associated with the activator protein 1 …
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Macrophage Diversity in the First Trimester Human Placenta: Phenotypes, Functions and Developmental Origins
… population of tissue-resident macrophages called Hofbauer cells (HBC), however the functions and developmental origins of these cells remain poorly defined. Our attempts to profile HBC in the first trimester human placenta revealed the presence of maternally-derived cells in placental digests. We …
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The Role of Apolipoprotein E in Pregnancy-Associated Protein Misfolding and Risk of Preeclampsia
… time in humans, that placental macrophages (Hofbauer cells), which share common ontogenetic origins with brain microglia and are known to decrease in number in PE, synthesize APOE. This observation was further validated in a combined mouse model of PE and AD induced by reduced uteroplacental …