Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 98 for “"Hemolytic"”.
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Characterization of Atypical Hemolytic Ornithobacterium rhinotracheale Isolates and Comparison with the Normal Non-Hemolytic Phenotype
… The type strain of ORT is characteristically non-hemolytic at least for 96 hours at 37°C on Columbia Blood Agar. In recent years, atypical isolates that rapidly produce hemolysis have been isolated with increasing frequency. A variety of in vitro tests were used to determine differences between …
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Treatment of Group A Beta-Hemolytic Streptococcal tonsillopharyngitis: Cephalosporins Versus Penicillins
<p>Group A beta-hemolytic streptococcal (GABHS) tonsillopharyngitis, also known as strep throat, has been a diagnosis of significant worldwide public health concern for decades. Serious post-infectious complications associated with untreated GABHS tonsillopharyngitis propel prompt diagnosis and …
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Rate of hemolytic antibody production by single cells in vivo in rabbits
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Drag reducing polymers as simple indicators of hemolytic potential in biomechanical devices
… reducing polymers can be simple indicators of hemolytic potential in biomechanical devices. Specifically, three different blood pumps, known as a left ventricle assist devices (LVADs) were operated in a test loop using an aqueous solution of polyethylene glycol (PEO, MW = 5000 kDa), a known …
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Managing alloimmunization, delayed hemolytic transfusion reactions, and hyper-hemolysis in sickle cell disease
… can become alloimmunized and develop delayed hemolytic transfusion reactions (DHTR), a life-threatening condition. The presentation of DHTR can vary, and its severity is unpredictable. In the most severe cases, patients destroy their own RBCs along with the transfused RBCs, a condition known …
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Genetic Factors Associated with Anti-Factor H Autoantibodies in Atypical Hemolytic Uremic Syndrome (aHUS)
Atypical hemolytic uremic syndrome (aHUS) is a rare form of thrombotic microangiopathy characterized by renal failure and determined by genetic and acquired defects of alternative pathway (AP) of the complement system. Autoantibodies against factor H (anti-FHs), a regulator of the AP, were reported …
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The hemolytic uremic syndrome in childhood. A focus on Shiga toxin and its consequences
Contains fulltext : 250224.pdf (Publisher’s version ) (Open Access)
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A study of the agglutinins in human sera for hemolytic streptococci from scarlet fever
Thesis (M.A.)--University of Kansas, Bacteriology, 1925.
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Studies of the idiotypic network through the use of a novel hemolytic plaque assay
… enumeration of Ab2 producing lymphocytes in a hemolytic plaque assay. This study utilizes a procedure that allows detection of Ab2 producing cells in such an assay. The procedure relies upon the insertion of the appropriate antibody (Ab1) into the membrane of indicator SRBC through a covalently …
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The prevalence of Group A Beta-Hemolytic Streptococci carriage in children in Africa: a systematic review
Asymptomatic children can be a major reservoir of pharyngeal Group A Streptococcus (GAS) with reported figures ranging from <10% to >20% in developing countries. There is a need to document GAS carriage in school children, which, together with the molecular characterisation (M-typing) of strains …
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Outcomes of Beta-Hemolytic Streptococcal Necrotizing Skin and Soft Tissue Infections and the Impact of Clindamycin Resistance
Background: Beta-hemolytic streptococci are frequently implicated in necrotizing soft tissue infections (NSTI). Clindamycin administration may improve outcomes in patients with serious streptococcal infections. However, clindamycin resistance is growing worldwide, and resistance patterns in NSTI …
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Assessment of motility and hemolytic activity in clinical isolates of Acinetobacter baumannii from University of Kentucky hospital, Lexington, KY
… ability to cause human disease, such as hemolytic activity and surface motility. The aim of this study was to determine the presence of these two virulent traits in clinical isolates. Forty-eight clinical isolates were recovered from University of Kentucky hospital in Lexington, KY. No …
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Cationic amphiphilic synthetic macromolecules with superior antibacterial activity
… with antimicrobial activity and very low hemolytic impact. Synthetic amphiphilic polymers attack bacteria directly to rupture the cell membrane through electrostatic and hydrophobic interactions. However, the toxicity of such synthetic amphiphilic polymers against mammalian cells have …
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The Influence of Certain Lytic Agents on the Oxygen Consumption of Dog Erythrocytes
The hemolytic action of methylene blue was reported in 1924 by Huyghabaert. Doge developed anemia following the admlnistration of the dye and methylene blue was shown to produce hemolysis in vitro (l). In 1934, Wendel and Hefley observed the hemolytic property of the dye and suggested its use in …
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Investigations into the digestive system proteases of Argiope aurantia (Araneae: Araneidae), hemolytic agents of spider venoms, and the role of both in necrotic arachnidism
… skin of rabbits. In an effort to determine the hemolytic agent in C. mildei venom, I found evidence for a phospholipase A2.</p><p>Through a combination of ion exchange chromatography, size exclusion chromatography, ultracentrifugation, and electrophoresis, an attempt was made to isolate several …
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Biochemical and Molecular Assessment of Toxicity of Primaquine Metabolites on Erythrocytes
… clinical use of PQ has been limited due to its hemolytic toxicity, especially in glucose-6-phosphate dehydrogenase deficient (G6PDd) individuals. Phenolic and quinone metabolites generated via cytochrome P450-dependent pathways appear to be responsible for hemolytic effects of PQ. However, the …
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Chemoenzymatic synthesis of an analogue of the potent antifungal mycosubtilin
… antibiotic activities,these molecules are also hemolytic in nature. Hence, the purpose of this study is to synthesize a potent antifungal analogue of mycosubtilin, with a modified β-amino fatty acid, devoid of any hemolytic activity. A chemoenzymatic approach was used to synthesize the cyclic …
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