Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 56 for “"Heart Valves"”.
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Polymeric Transcatheter Heart Valves
Rheumatic heart disease (RHD) is one of the main causes of heart disease in the emerging world. Once the disease has become symptomatic valve repair or replacement is the only treatment currently available. Commercial bioprosthetic valves (surgical and transcatheter) suffer from calcification and …
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Paravalvular sealing pf percutaneous heart valves
… is still sought. Commercial transcatheter heart valves (THV's) rely on sealing skirts made from treated pericardium or polyethylene terephthalate (PET) fabrics. The current study was aimed at developing novel electrospun skirts for the minimization of PVR in THV's. Thermoplastic …
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Bioprosthetic heart valves : ultrastructure and calcification
… most widely used commercially produced tissue heart valves. Since stentless bioprostheses represent the latest promising trend in the development of biological heart valves, stentless models of the following makes were compared: Baxter, Medtronic, St. Jude and Biocor. Due to the fact that the …
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A Computational Model for Design Optimization of Bioprosthetic Heart Valves
<p>Heart valves play an important role in directing blood flow and preventing back flow in the heart. Design and development of bioprosthetic heart valves has been a major focus of research in the field of cardiovascular engineering as they are a better replacement for natural diseased valves than …
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Hybrid Electrospun Transcatheter Aortic Heart Valves for Tissue Engineering Applications
Bioprosthetic and mechanical heart valves are suboptimal due to both calcific degeneration and the need for lifelong anticoagulation treatment. Tissue engineering (TE) has the potential to overcome these and other shortcomings by providing viable valves capable of growth, remodelling, and repair. …
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Complications of anticoagulation in pregnant women with mechanical heart valves
Includes abstract. Includes bibliographical references.
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3-DIMENSIONAL NUMERICAL AND EXPERIMENTAL STUDIES TO MODEL ARTIFICIAL HEART VALVES HEMODYNAMICS
The characterization of the artificial heart valves flow fields is a crucial step to evaluate the performances on improving heart valve engineering. With the advancement of Computational Fluid Dynamics, we are able to study the complex hemodynamics in details such as stagnation, recirculation zones …
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CD133 Antibody Conjugation to Decellularized Human Heart Valves For Circulating Endothelial Progenitor Cell Capture
The long term efficacy of heart valve bioprostheses is limited by progressive degeneration characterized by immune mediated inflammation and calcification. To avoid this degeneration, decellularized heart valves with functionalized surfaces capable of rapid in vivo endothelialization have been …
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Fully Coupled Fluid Structure Interaction Simulation of Bioprosthetic Heart Valves: A Numerical and Experimental Analysis
… to consider accurate properties of bioprosthetic heart valves (BHVs), such as density and mechanical properties. Previous computational studies assumed (bovine pericardium) BP used in BHVs density was comparable to water or blood. Yet, BP is subjected to multiple treatments like fixation and …
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Haemorrhage and Other Complications in Pregnant Women on Anticoagulation for Mechanical Heart Valves; a Prospective Observational Cohort Study
… pregnant patients with mechanical heart valves until 42 days postpartum. Methods: In a tertiary single-centre, prospective cohort, 178 consecutive patients at the cardiac-obstetric clinic were screened for warfarin use between 1 July 2010 and 31 December 2015. Of 33 pregnancies …
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Application of passive flow control to mitigate the thromboembolic potential of bileaflet mechanical heart valves: an in-vitro study
Implantation of a bileaflet mechanical heart valve (BMHV) continues to be associated with risk of thromboembolic complications despite anti-coagulation therapy. Mechanical heart valves have been the gold standard in valve heart replacement since the 1950s with BMHVs currently still being the valve …
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The Influence of Normal Physiological Forces on Porcine Aortic Heart Valves in a Sterile Ex Vivo Pulsatile Organ Culture System
… characteristics of native porcine aortic valves cultured in the system. Collagen, sGAG and elastin content of the valve leaflets were measured and cusp morphology, cell phenotype, cell proliferation and apoptosis were examined. Presence of endothelial cells (ECs) on the leaflet surface was …
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