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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 75 for “"HNO"”.
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Newly Designed HNO Triggered Prodrugs
… reduced and protonated derivative of NO, HNO has also been determined to play important biological roles. Because of HNO’s high reactivity, its detection has been difficult and many methods including fluorescent copper compounds and electrochemical methods have been devised. Our group has …
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Long-wavelength, reaction-based, fluorescent sensors for HNO and mobile zinc
… these species are nitric oxide (NO), nitroxyl (HNO), and mobile zinc. Maintaining the homeostasis of these signaling molecules is vital and a deeper comprehension of their roles could help in understanding the pathology of specific diseases associated with their dysregulation. One method used to …
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Acyloxy Nitroso Compounds as HNO Donors and Their Reactions with Thiol and Heme Containing Proteins
Nitroxyl (HNO), a nitrogen monoxide with distinct chemistry and biology, has gained interest as a potential treatment of congestive heart failure through the ability of the HNO donor, Angeli's salt (AS), to evoke positive inotropic effects in canine cardiac muscle. The release of nitrite during …
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The Role of Phospholamban Cysteines in the Activation of the Cardiac Sarcoplasmic Reticulum Ca2+ Pump by Nitroxyl (HNO)
… patient prognosis remains poor. Nitroxyl (HNO), a new candidate heart failure drug therapy, has been shown to enhance overall cardiovascular function in both healthy and failing hearts, at least in part, by increasing Ca²⁺ re-uptake into the CSR. Previous research has shown that activation …
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Developing Detection Methods for Nitroxyl
Accurate detection of nitroxyl (HNO) is essential to understanding its bioactivity, metabolism, and relation to health and disease. However, detection and quantitation of HNO has been complicated by the rapid self-consumption of HNO through irreversible dimerization, poor selectivity of trapping …
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Altersabhängigkeit der objektiven und quantitativen neurootologischen Funktionsmessergebnisse bei 350 Vertigo-Patienten aus der Neurootologie der Würzburger Universitäts-HNO-Klinik
Die Dissertation beschreibt, dass die menschliche Gleichgewichtsregulation zur Aufrechterhaltung der Stellung im Raume, zur Regulation der Blickmechanismen, aber auch zur inneren Erzielung eines gleichgewichtes auf komplizierten kybernetischen Regelkreisen beruht. Mit Hilfe eines umpfangreichen …
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Investigation of water vapor effects on the detection of nitric acid vapor with the tungstic acid technique
… has been successfully used to measure gaseous HNO₃ in the presence of water vapor. The TAT is based on the diffusion of gaseous HNO₃ to the interior walls of a tube coated with tungsten VI oxide (WO₃), where it is selectively chemisorbed. The collected HNO₃ sample is thermally desorbed from the …
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Degradable Polymers for the Controlled Delivery of Bioactive Small Molecules
… sulfur dioxide, hydrogen cyanide, and nitroxyl (HNO). This dissertation covers compounds that release HNO, which possesses similar functions to NO (cardioprotection and vasodilation) but has been studied much less. While HNO, H2S, and RSSH have vital biological functions, they also have short …
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Reactions of Nitroxyl and Nitrite in Blood
… a nitroxyl (HNO) and nitrite (NO<sub>2</sub><super>-</super>) donor, on plasma Hb oxidation, and on the vasoactivity of plasma Hb. Both HNO and nitrite are known to oxidize oxyHb to metHb. We hypothesized that AS could ameliorate hemolysis-associated pathology …
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Physical Mechanisms of Ca-ATPase Regulation in the Heart
… is not understood. Conversely, nitroxyl (HNO), a new candidate for drug therapy for congestive heart failure (CHF), improves overall cardiovascular function by increasing Ca-ATPase activity in the heart. However, the physical mechanism for this activation is unknown. Therefore, we have …
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Lungenkrebs und Kopf-Hals-Tumore : Unterschiede und Gemeinsamkeiten im Spiegel des Internets
… am Beispiel der Bronchialkarzinome und HNO-Karzinome. Die Patientenbefragung wurde anhand eines 32 Kriterien umfassenden Fragebogens im Zeitraum vom 07.02.2001 bis zum 23.11.2001 durchgeführt. Mit einer speziellen Software wurden insgesamt 11.400 URL-Adressen zu den Themen …
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Hörergebnisse nach transtemporaler Resektion von Akustikusneurinomen
… in der Zeit von 1989 bis 2000 an der Univ.-HNO-Klinik Würzburg auf transtemorale Weise operiert wurden. Es wurden anmestische Daten, Tumorgröße und das postoperative Hörvermögen anhand der Aktenlage ausgewertet.
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Phosphine-Mediated Ligations: A Powerful and Versatile Method for the Selective Chemical Detection of Nitroxyl
… disaggregation and vasorelaxation. Nitroxyl (HNO), the product of NO reduction and protonation, increases myocardial contractility and elicits vasodilation, likely through modifications of select thiol proteins, a physiological profile distinct from NO.
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Remediation of contaminated land and solutions with binders derived from waste material.
… 50ml of de-ionised (DI) water or 50 ml of 0.1M HNO[3] or 0.01M HNO[3] was added. The mixture was shaken on a flat bed shaker for 2 hours, and then filtered using a Whatman No 542 filter paper. The lead concentration in the filtrate was determined by inductively coupled plasma-atomic emission …
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